Harbor Island Vacation Rentals

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Our top choices for Harbor Island vacation rentals

Condo in Saint Helena Island

Harbor Island #D112
10.0 out of 10, Exceptional, (3)
"Everything was great, thank you "
United States
Nicolae A.
$337 nightly
The price is $371
Dec 28 - Dec 29
Total with taxes and fees
Harbor Island #D112
9.4 out of 10, Exceptional, (6)
"Great stay for the price!!"
United States
Randall
$159 nightly
The price is $175
Dec 27 - Dec 28
Total with taxes and fees
Beautiful Vintage Airstream, Beaufort SC-Enjoy the Journey
9.6 out of 10, Exceptional, (24)
"We love this place. I stay here frequently and enjoy every time. Close and convenient to everything Beaufort has to offer."
United States
Nate P.
$159 nightly
The price is $175
Dec 27 - Dec 28
Total with taxes and fees
Amazing Airstream, Beaufort, SC-Enjoy the Journey!
9.8 out of 10, Exceptional, (7)
"The host was very nice and the check in process was fast. The house is very nice and had everything we needed. I would definitely stay here again."
United States
Venus S.
$220 nightly
The price is $242
Dec 28 - Dec 29
Total with taxes and fees
Beaufort SC Newly Renovated 2 Bedroom 2 Bath Sleeps 6
2.0 star property
8.0 out of 10, Very Good, (2)
"No proper communication and things broke inside or not working "
United States
Alejandra
$291 nightly
The price is $303
Jan 7 - Jan 8, 2026
Total with taxes and fees
Beach Getaway 2BR w/ Pool + Modern Comforts

Condo resort in Mid Island

Marriott's Barony Beach Club
3.5 star property
9.6 out of 10, Exceptional, (243)
"Great place for vacation on the beach, nice, clean and quiet areas "
United States
Larisa
$186 nightly
The price is $205
Jan 4 - Jan 5, 2026
Total with taxes and fees
Marriott's Barony Beach Club
9.6 out of 10, Exceptional, (4)
"Relaxation was much needed and host was very accommodating and made check in easy. The room was clean, and perfect for our stay. The location was perfect. "
United States
Felicia R.
$310 nightly
The price is $341
Jan 1 - Jan 2, 2026
Total with taxes and fees
522 Sunsuite - New to VRBO! Resort Access Included!
9.4 out of 10, Exceptional, (53)
"Relaxing and comfortable stay"
United States
cheryl j.
$262 nightly
The price is $288
Jan 4 - Jan 5, 2026
Total with taxes and fees
Tranquility by the Beach 1st Fl Sleeps 6,King Bed
8.8 out of 10, Excellent, (11)
"Port Royal is charming & this was a great place to stay. Right next to a park, very clean and super comfy!"
United States
Julie S.
$197 nightly
The price is $216
Jan 4 - Jan 5, 2026
Total with taxes and fees
Experience USMC History: 10 min to Parris Island
9.8 out of 10, Exceptional, (11)
"This was a super getaway. From the friendly gate greeting, the comfortable, attractive room, the quick walk to the beach and everything for a wonderful 2 night stay! We hope to visit again!"
United States
Robbie
$328 nightly
The price is $361
Dec 27 - Dec 28
Total with taxes and fees
501 Sunsuite - New to VRBO! Resort Access Included!
9.2 out of 10, Wonderful, (5)
"Everything is was excellent!!!"
United States
Cheryl S.
$293 nightly
The price is $309
Dec 27 - Dec 28
Total with taxes and fees
Come Enjoy this recently remodeled Villa
9.6 out of 10, Exceptional, (33)
"Very nice property, convenient to the beach and restaurants "
United States
Shaun H.
$252 nightly
The price is $282
Jan 3 - Jan 4, 2026
Total with taxes and fees
SPECIAL‼️ COASTAL COTTAGE SLEEPS 4 SWIMMING, FISHING, TURTLE TOURS, GOLF, BIKING
10.0 out of 10, Exceptional, (2)
"Wife and I celebrated our 25th Wedding Anniversary here at Fripp. Location was amazing! Less than a 2 minute walk to the beach. Great golf, restaurants and lots of gators and deer!!"
United States
adam r.
$335 nightly
The price is $369
Jan 1 - Jan 2, 2026
Total with taxes and fees
New to VRBO! Welcome to Fripp Island and this Newly Renovated Sunsuite! Resort Access Included!
10.0 out of 10, Exceptional, (19)
"Great property "
United States
Caleb C.
$193 nightly
The price is $212
Dec 28 - Dec 29
Total with taxes and fees
The Grey Pearl on Port Royal's Battery Creek
9.6 out of 10, Exceptional, (4)
"Loved it. "
United States
Ronald T.
$340 nightly
The price is $374
Dec 27 - Dec 28
Total with taxes and fees
512 Sunsuite - New to VRBO - Resort Access Included!
9.8 out of 10, Exceptional, (45)
"Great condo. Very clean, well maintained."
United States
Kenton A.
$191 nightly
The price is $210
Dec 27 - Dec 28
Total with taxes and fees
Charming Coastal Casa on Beaufort's Battery Creek
8.8 out of 10, Excellent, (3)
"Great place everything was clean, comfortable and a perfect size for a weekend getaway."
United States
Iboga S.
$268 nightly
The price is $300
Dec 27 - Dec 28
Total with taxes and fees
Modern Coastal Retreat Near the Beach & Golf - Sleeps 4
9.4 out of 10, Exceptional, (53)
"Had a great time. Location was great about a 2 minute walk to beach. Condo was great"
United States
Anonymous traveler
$253 nightly
The price is $278
Jan 25 - Jan 26, 2026
Total with taxes and fees
Beachy chic, steps from the beach!
9.8 out of 10, Exceptional, (151)
"The property was nice and comfortable. Perfect for a couples get away. We only stayed one night, but were impressed by the property. "
United States
Stephen F.
$175 nightly
The price is $196
Dec 28 - Dec 29
Total with taxes and fees
All Inn on Edisto - Cozy Studio Condo Close to Everything

Vacation Home in Mid Island

Beach. View. Suite. 1 br. 1 ba. Sleeps 5
9.6 out of 10, Exceptional, (91)
"Great place great vacation thank you"
United States
Brett S.
$220 nightly
The price is $242
Dec 29 - Dec 30
Total with taxes and fees
Beach. View. Suite. 1 br. 1 ba. Sleeps 5
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Harbor Island Hotel Reviews

Find out more about Harbor Island

Everything you need to know about Harbor Island vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Harbor Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Harbor Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Harbor Island vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Harbor Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Harbor Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $205 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Harbor Island rentals

At Expedia, we put the best Harbor Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Harbor Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Harbor Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Harbor Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Harbor Island?

Yes, we offer vacation rentals near well known points of interest in Harbor Island, or you can select a more secluded option if you're looking for relaxation. Harbor Island is known for its parks and waterfront. Make sure you have time to check out the golf courses while you're in the area.

What's the top vacation rental that Harbor Island has to offer?

Private Pool, Peaceful Location, Walk to Beach Home!: You might want to consider this vacation home rental near Harbor Island, which is located near the beach and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a private yard.

How many vacation rentals are there in Harbor Island?

With 89 Expedia vacation rentals, you're sure to find just the right place for your Harbor Island stay.

What can I see and do in Harbor Island?

Explore the area and family-friendly sights such as Sea Wolf Charters, or get out into nature at a spot like Fripp Island Beach. In the larger area, you’ll find Penn Center and Coosaw Island.

What are vacation rentals like in Harbor Island?

Vacation rentals are private accommodations you can book for a short or long stay in Harbor Island. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll have a home away from home. If you're concerned about a clean environment, a vacation rental can provide a sense of privacy away from public hotel elevators and bustling concierge desks while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive option for a family trip.