A marshy landscape with water, trees, and a distant city skyline.

Ladys Island Vacation Rentals

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Check prices for these dates

In two weeks
Jul 10 - Jul 12
In two months
Aug 21 - Aug 23
In three months
Sep 18 - Sep 20
In four months
Oct 16 - Oct 18

Our top choices for Ladys Island vacation rentals

Interior

Cozy 3 bedroom house situated close to several local attractions in Beaufort, SC

Cozy 3 bedroom house situated close to several local attractions in Beaufort, SC
Beaufort
10.0 out of 10, Exceptional, (2 reviews)
"Absolutely wonderful! Spacious, decorated beautifully with a classy seaside ambience, and both living space and bedrooms are super comfortable. Kitchen has everything including a great refrigerator and stove. Outdoors has a sitting area close to grill. Ashley has put lots of effort making her abode a great retreat and location couldn't be better. Situated between the beach and heart of Beaufort with ample grocery shopping minutes away. Would love to return one day."
United States
Elaine S.
Cozy 3 bedroom house situated close to several local attractions in Beaufort, SC
Fridge, microwave, oven, stovetop

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive

Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive
Beaufort
10.0 out of 10, Exceptional, (11 reviews)
"Great location close to downtown newly renovated home with everything we could ask for. Would definitely book again on our next trip"
United States
adam s.
$406 nightly
The price is $447
Jun 29 - Jun 30
Total with taxes and fees
Relax under the Shade of a Live Oak! MCRD Paris Island and MCAS 10 Minute Drive
Interior

C & N Lodging, Bluffton, SC

C & N Lodging, Bluffton, SC
Bluffton
9.6 out of 10, Exceptional, (7 reviews)
"We had a great stay. Communication was awesome and the place was great. You couldn't ask for a better location for Bluffton. Garage apartment and was taken care of really well. If older be aware there are stairs which is no problem but may not suit everyone. Thanks Clynise for being an awesome host."
United States
Randy
$208 nightly
The price is $229
Jun 29 - Jun 30
Total with taxes and fees
C & N Lodging, Bluffton, SC
TV, fireplace

Swim & Relax: St Helena Island Gem w/ Deck!

Swim & Relax: St Helena Island Gem w/ Deck!
St. Helena Island
9.8 out of 10, Exceptional, (51 reviews)
"Property was beautiful, well stocked, convenient to area sights. We enjoyed our stay."
United States
Bonnie S.
$352 nightly
The price is $385
Jul 2 - Jul 3
Total with taxes and fees
Swim & Relax: St Helena Island Gem w/ Deck!
Interior

The Grey Pearl on Port Royal's Battery Creek

The Grey Pearl on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (33 reviews)
"Great property "
United States
Caleb C.
$183 nightly
The price is $201
Jun 29 - Jun 30
Total with taxes and fees
The Grey Pearl on Port Royal's Battery Creek
Fridge, microwave, oven, stovetop

Gorgeous Waterfront Battery Creek Retreat

Gorgeous Waterfront Battery Creek Retreat
Beaufort
10.0 out of 10, Exceptional, (110 reviews)
"Place was as pictured Very peaceful and beautiful "
United States
Randy O.
$232 nightly
The price is $255
Jul 18 - Jul 19
Total with taxes and fees
Gorgeous Waterfront Battery Creek Retreat
On the beach

Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Tranquility by the Beach 1st Fl Sleeps 6,King Bed
Mid Island
9.4 out of 10, Exceptional, (61 reviews)
"Relaxing and comfortable stay"
United States
cheryl j.
$332 nightly
The price is $365
Jun 30 - Jul 1
Total with taxes and fees
Tranquility by the Beach 1st Fl Sleeps 6,King Bed
Property grounds

Charming Coastal Casa on Beaufort's Battery Creek

Charming Coastal Casa on Beaufort's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (48 reviews)
"Clean, cozy, and close to Parris Island!"
United States
Jeremy G.
$187 nightly
The price is $206
Jun 29 - Jun 30
Total with taxes and fees
Charming Coastal Casa on Beaufort's Battery Creek
Terrace/patio

Beaufort's Blue Heron Hideaway on Battery Creek

Beaufort's Blue Heron Hideaway on Battery Creek
Beaufort
9.4 out of 10, Exceptional, (41 reviews)
"Nice location. Did not have an issue finding it. View was beautiful. Bed was firm, furniture and decor was very nice. "
United States
Kim K.
$203 nightly
The price is $223
Jul 5 - Jul 6
Total with taxes and fees
Beaufort's Blue Heron Hideaway on Battery Creek
Interior

Amazing Airstream, Beaufort, SC-Enjoy the Journey!

Amazing Airstream, Beaufort, SC-Enjoy the Journey!
Beaufort
9.4 out of 10, Exceptional, (28 reviews)
"We love this place. I stay here frequently and enjoy every time. Close and convenient to everything Beaufort has to offer."
United States
Nate P.
$159 nightly
The price is $175
Jun 29 - Jun 30
Total with taxes and fees
Amazing Airstream, Beaufort, SC-Enjoy the Journey!
Fridge, microwave, coffee/tea maker, cookware/dishes/utensils

Beautiful Vintage Airstream, Beaufort SC-Enjoy the Journey

Beautiful Vintage Airstream, Beaufort SC-Enjoy the Journey
Beaufort
9.4 out of 10, Exceptional, (6 reviews)
"Great stay for the price!!"
United States
Randall
$159 nightly
The price is $175
Jun 29 - Jun 30
Total with taxes and fees
Beautiful Vintage Airstream, Beaufort SC-Enjoy the Journey
Smart TV

Legacy Loft in Award-Winning Habersham Community

Legacy Loft in Award-Winning Habersham Community
Habersham
10.0 out of 10, Exceptional, (17 reviews)
"We loved the location! "
United States
Greg F.
$293 nightly
The price is $322
Jul 7 - Jul 8
Total with taxes and fees
Legacy Loft in Award-Winning Habersham Community
1 bedroom, free WiFi, bed sheets

Cozy Edisto Condo-Close to the Beach!

Cozy Edisto Condo-Close to the Beach!
Edisto Beach
9.0 out of 10, Wonderful, (106 reviews)
"Cozy and enjoyable condo, everything was great!"
United States
Vic C.
$197 nightly
The price is $221
Jul 8 - Jul 9
Total with taxes and fees
Cozy Edisto Condo-Close to the Beach!
Exterior

501 Sunsuite

501 Sunsuite
Fripp Island
9.6 out of 10, Exceptional, (15 reviews)
"This was a super getaway. From the friendly gate greeting, the comfortable, attractive room, the quick walk to the beach and everything for a wonderful 2 night stay! We hope to visit again!"
United States
Robbie
$433 nightly
The price is $476
Jul 12 - Jul 13
Total with taxes and fees
501 Sunsuite
Terrace/patio

Modern Coastal Escape on Beaufort's Battery Creek

Modern Coastal Escape on Beaufort's Battery Creek
Beaufort
9.8 out of 10, Exceptional, (40 reviews)
"We enjoyed the stay. Heading out now. Thank you "
United States
Patricia C.
$238 nightly
The price is $262
Jun 29 - Jun 30
Total with taxes and fees
Modern Coastal Escape on Beaufort's Battery Creek
Smart TV

Mariners' Nautical Nest on Port Royal's Battery Creek

Mariners' Nautical Nest on Port Royal's Battery Creek
Beaufort
10.0 out of 10, Exceptional, (36 reviews)
"Perfect location "
United States
Jayda M.
$224 nightly
The price is $246
Jul 19 - Jul 20
Total with taxes and fees
Mariners' Nautical Nest on Port Royal's Battery Creek
Interior

SeaClusion-Oceanview, Mini split AC, Beach Chairs

SeaClusion-Oceanview, Mini split AC, Beach Chairs
South End
9.6 out of 10, Exceptional, (71 reviews)
"Location cleanliness cozy the beach 3min walk its a great spot"
United States
kenneth
$245 nightly
The price is $270
Jul 7 - Jul 8
Total with taxes and fees
SeaClusion-Oceanview, Mini split AC, Beach Chairs
Beach nearby, beach towels

Frippin Fun Vacation - Fripp Island

Frippin Fun Vacation - Fripp Island
Saint Helena Island
9.4 out of 10, Exceptional, (41 reviews)
"My husband and I had a great vacation! The view was wonderful and we saw an abundance of wildlife. Very relaxing!"
United States
Amy C.
$376 nightly
The price is $414
Jul 15 - Jul 16
Total with taxes and fees
Frippin Fun Vacation - Fripp Island
Exterior

Heart of Historic Bluffton BEST LOCATION, Charming Cottage THIS IS THE ONE

Heart of Historic Bluffton BEST LOCATION, Charming Cottage THIS IS THE ONE
Old Town Bluffton
9.4 out of 10, Exceptional, (140 reviews)
"Loved my stay. Will definitely be back."
United States
Angie H.
Heart of Historic Bluffton BEST LOCATION, Charming Cottage THIS IS THE ONE
Beach nearby

Old Town + Modern 4 BR + Fire Pit + EV Charger

Old Town + Modern 4 BR + Fire Pit + EV Charger
Old Town Bluffton
9.4 out of 10, Exceptional, (29 reviews)
"Great house. Close to all the restaurants would come back again. "
United States
Marty H.
$456 nightly
The price is $475
Jul 5 - Jul 6
Total with taxes and fees
Old Town + Modern 4 BR + Fire Pit + EV Charger
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Ladys Island Hotel Reviews

Holiday Inn Express Hilton Head Island by IHG

Holiday Inn Express Hilton Head Island by IHG

8/10 Good
"Breakfast included was excellent but $10/per day parking. Ice machine and washer and dryers only on certain floors. No suna or hot tub."
Sharyl 3-night trip
Posted less than an hour ago
Holiday Inn Express Hilton Head Island by IHG

Find out more about Ladys Island

Everything you need to know about Ladys Island vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Ladys Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Ladys Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Ladys Island vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Ladys Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Ladys Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $221 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Ladys Island rentals

At Expedia, we put the best Ladys Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Ladys Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Ladys Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Ladys Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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