
Opelousas Vacations
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Your Opelousas Vacation
There's no better way to embark on an adventure than with one of our vacation packages to Opelousas. The rich history and cultural experiences are a couple of the countless reasons to spend some time in this interesting city. Be sure to spend time sightseeing during your trip to Opelousas. Louisiana Orphan Train Museum and St. Landry Catholic Church are some well-known attractions to check out. Don't delay visiting this destination any longer. Your dream Opelousas vacation is a couple of clicks away with Expedia.
Stay near popular Opelousas attractions
Opelousas Hotel Deals

Days Inn & Suites by Wyndham Opelousas
5761 I-49 S Service Rd Opelousas LA
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $81 total per night from Dec 6 to Dec 7
$81 total
Dec 6 - Dec 7
Total with taxes and fees
7/10 Good! (786 reviews)
"The property overall was run down. Someone had a dog that barked at all hours of the night."
Reviewed on Nov 11, 2026

Hampton Inn Opelousas
1700 Commerce Blvd Opelousas LA
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $119 total per night from Nov 22 to Nov 23
$119 total
Nov 22 - Nov 23
Total with taxes and fees
8.4/10 Very Good! (389 reviews)
"The room was clean, but the bathroom needed some scrubbing. Especially, the bathtub (drainage) and the floor around the tub."
Reviewed on Nov 13, 2026

Holiday Inn Express & Suites Opelousas by IHG
5696 I-49 N Service Rd Opelousas LA
Fully refundable
$135 nightly
The price is $159 total per night from Nov 22 to Nov 23
$159 total
Nov 22 - Nov 23
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Opelousas Vacation Packages
Opelousas Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lafayette Regional Airport (LFT) |
Population | 16,600 |
Max Temp Winter | 60ºF |
Max Temp Summer | 90ºF |
Top Sights | Louisiana Orphan Train Museum and St. Landry Catholic Church |
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