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Find hotels in Panacea, FL from $77

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Compare 496 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Panacea hotels

The Moorings Hotel and Marina

2.5 star property
8.4 out of 10, Very Good, (35)
"Quaint hotel on marina with old Florida charm. Room was very clean but also very musty - mildew coming from AC unit was overwhelming. Bed was awful - literally lumpy with loose headboard that sounded like an accordion when you moved at all. We wedged towels to shut it up. Almost left to pay to stay at a second hotel. "
$153 nightly
The price is $169
Oct 1 - Oct 2
Total with taxes and fees
The Moorings Hotel and Marina

The Panacea Motel

2.0 star property
9.0 out of 10, Wonderful, (114)
"In town for a fishing tournament, it was perfect place to stay."
$107 nightly
The price is $120
Sep 14 - Sep 15
Total with taxes and fees
The Panacea Motel

Franklin Inn

2.0 star property
7.8 out of 10, Good, (435)
"Food options are close and very good"
$69 nightly
The price is $77
Sep 24 - Sep 25
Total with taxes and fees
Franklin Inn

The Lodge at Wakulla Springs

3.0 star property
9.4 out of 10, Exceptional, (984)
"We love staying here!!"
$89 nightly
The price is $100
Sep 10 - Sep 11
Total with taxes and fees
The Lodge at Wakulla Springs

Wildwood Inn

3.0 star property
8.6 out of 10, Excellent, (1001)
"Good"
$143 nightly
The price is $159
Sep 8 - Sep 9
Total with taxes and fees
Wildwood Inn

Best Western Wakulla Inn & Suites

2.5 star property
8.8 out of 10, Excellent, (919)
"We absolutely love this venue and stay here when we visit our family every year! "
$123 nightly
The price is $137
Oct 2 - Oct 3
Total with taxes and fees
Best Western Wakulla Inn & Suites

St James Bay Golf & Pickleball Resort

3.5 star property
9.0 out of 10, Wonderful, (355)
"Nice out of the way place. Room arrangement is rather tight."
$156 nightly
The price is $173
Sep 10 - Sep 11
Total with taxes and fees
St James Bay Golf & Pickleball Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out family-friendly hotels in Panacea

Pet-friendly hotels in Panacea you'll enjoy

Hotels with a pool in Panacea may fit your trip

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Panacea attractions

Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

Top Panacea Hotel Reviews

More cheap stays in Panacea

More cheap stays in Panacea

Hotels in Panacea with star-rating

Hotels in Panacea with star-rating

Find out more about Panacea

Find out more about Panacea

Top reasons to visit Panacea

  • Stunning Beaches: Enjoy picturesque beaches perfect for sunbathing and relaxation.
  • Outdoor Adventures: Explore nearby state parks and charming islands for hiking, fishing, and wildlife observation.
  • Family-Friendly Activities: Engage in a variety of activities suitable for all ages, ensuring fun for the whole family.
  • Charming Accommodations: Choose from a range of cozy motels and guesthouses that cater to diverse traveler needs.
  • Warm Local Hospitality: Experience the welcoming nature of the Panacea community, enhancing your vacation experience.

Find great hotels near Panacea

Discover the charm of Panacea, Florida, where a variety of accommodations await you. From cozy motels to inviting guesthouses, you'll find options that cater to adventurous spirits and pet lovers alike. Whether you're seeking a golf-themed getaway or a beachside retreat, Panacea's hotels provide the perfect base for your vacation. Explore reviews and discover the ideal lodging for your memorable stay in this beautiful coastal town.

  • Hyatt House Tallahassee Capitol – University: Nestled 29 miles from Panacea, the Hyatt House Tallahassee Capitol – University is a welcoming retreat tailored for families, business travelers, and pet owners. This 3-star hotel boasts a range of amenities designed for productivity and comfort, including an accessible business center and meeting rooms. Families will appreciate the child-friendly features such as free cribs and safety measures like window guards. With a pet-friendly policy that permits certain pets, it ensures that no family member is left behind. Guests rave about the spacious accommodations and the supportive staff, making it a top choice for a versatile vacation.
  • Best Western Wakulla Inn & Suites: Located a mere 6 miles from Panacea, Best Western Wakulla Inn & Suites provides a perfect blend of business amenities and adventure opportunities. This hotel is equipped with multiple meeting rooms and a 24-hour business center, catering to corporate travelers. Adventure seekers can indulge in outdoor activities such as sailing, kayaking, and hiking—all nearby. Guests enjoy the friendly atmosphere and convenient location, making it an ideal base for exploring the natural beauty of Wakulla County while enjoying modern comforts.
  • Magnuson Hotel Wildwood Inn: Just 7 miles from Panacea, the Magnuson Hotel Wildwood Inn is a 3-star gem that caters to business travelers, adventure enthusiasts, and pet lovers alike. With business amenities like an accessible business center and meeting rooms, it ensures a productive stay. Guests can explore a range of adventurous activities, from snorkeling to fishing, all within reach. The hotel’s pet-friendly policy allows for a hassle-free stay for furry companions, creating a welcoming environment for all. Visitors appreciate the friendly service and the hotel’s commitment to making every stay enjoyable.

Where to stay in Panacea

Panacea, Florida, offers a delightful coastal getaway perfect for beach lovers and outdoor enthusiasts. Experience the serene charm of the oceanfront while enjoying family-friendly activities and the warm hospitality of the local community. Nearby, explore scenic spots that promise relaxation and recreation, making your vacation a truly rejuvenating escape. Whether you're seeking a secluded retreat or lively beach fun, Panacea and its surrounding areas have something special for every traveler.

  • Alligator Point: Nestled near Panacea, Alligator Point is a charming village that offers a serene beach experience. Known for its scenic beauty, the area sees a peak in visitors from May to July. Travelers flock here for outdoor activities and breathtaking views. Popular spots include local resorts, golf courses, and recreational areas. Nature enthusiasts will love the nearby beaches, national state parks, and wetlands that provide ample opportunities for exploration and relaxation.
  • Saint Teresa: A quaint village also located in the Panacea area, Saint Teresa attracts visitors with its picturesque beaches and outdoor adventures. The peak travel season occurs in March and again during June to July, making it a popular summer getaway. This village is perfect for golf lovers and those looking to enjoy recreational activities amidst beautiful scenery. With its proximity to national state parks and wetlands, Saint Teresa is ideal for those seeking a nature-filled escape.
  • Ochlockonee Bay: Located just a short distance from Panacea, Ochlockonee Bay is a vibrant village known for its outdoor adventures and stunning scenery. Visitors typically arrive from May to July, drawn by the area's recreational offerings and natural beauty. Enjoy the local beaches, explore the national state parks, and indulge in activities at nearby resorts and golf courses. Ochlockonee Bay is perfect for those seeking adventure and relaxation in a picturesque setting.

Things to do in and around Panacea

Panacea, Florida, is perfect for beach and outdoor enthusiasts, offering stunning scenery and a variety of activities. Visitors can enjoy recreational areas, educational experiences, and relaxing resorts. Outdoor seating options enhance the experience, allowing guests to soak in the natural beauty. Whether you’re seeking adventure or simply a peaceful getaway, Panacea promises some of the best outdoor experiences for a memorable vacation.

Shopping

In Panacea, you can shop at local spots like the Flea Market Tallahassee, which offers a variety of goods 25 miles away. If you're up for a drive, visit the Tallahassee Downtown Market and Governor's Square Mall for a diverse shopping experience filled with entertainment and family-friendly options, both located 29 miles away.

Recreation

Enjoy a round of golf at St. James Bay Golf Club, where you can immerse yourself in the lush outdoor scenery. For relaxation, Woolley Park offers a serene setting to unwind, while Morrison Hammock Scenic Area invites you to connect with nature in a tranquil environment.

Adventure

Explore the Tallahassee-Saint Marks Historic Railroad Trail State Park, located 27 miles from Panacea, where you can enjoy scenic hikes amidst lush landscapes. The nearby Tallahassee-St. Marks Historic Railroad State Trail, 29 miles away, and Saint Marks Trail, 28 miles away, offer similar adventures in beautiful outdoor settings.

Nightlife

Experience the vibrant nightlife by visiting Theatre Tallahassee, just 31 miles from Panacea, where you can enjoy captivating performances in a romantic setting. The theater offers a perfect blend of culture and entertainment for families and couples alike.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Panacea

To save money on your trip to Panacea, Florida, consider visiting during the cheaper months of July and December to January, with Mondays being the least expensive day for accommodations. Use Expedia to customize your hotel search by budget and eco-friendly options, and sort prices from lowest to highest for the best deals. Bundle your hotel with flights and activities for extra savings, and join the One Key membership for exclusive discounts and future cash rewards. Look for free activities in the area to enhance your experience without stretching your budget.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Panacea are July and December to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Panacea is Monday. The most expensive day to stay in Panacea is Friday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to customize your preferences, such as your budget, desired location, and the type of hotel you prefer. For instance, selecting the Eco-certified option will show you sustainable and environmentally-friendly hotels that are currently available. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your Panacea hotel reservation with your flights and activities through an Expedia package deal.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions in Panacea

Panacea, Florida, is a delightful destination for beach lovers and outdoor enthusiasts, offering stunning scenery and a variety of attractions. Visitors can explore beautiful beaches, the nearby state park, and charming islands, all perfect for enjoying nature. Whether you're looking to relax by the water or embark on outdoor adventures, Panacea provides an ideal setting for a memorable vacation experience.

  • Alligator Point Beach: This charming beach offers a serene escape with its soft sands and gentle waves, perfect for sunbathing, picnicking, or beachcombing. The tranquil vibe makes it an ideal spot for relaxation and enjoying breathtaking sunsets.
  • Bald Point State Park: Experience adventure and stunning scenery at this expansive park, featuring scenic trails, wildlife viewing, and opportunities for hiking and kayaking. The park's diverse landscapes provide a perfect backdrop for outdoor enthusiasts.
  • USS Mohawk CGC Veterans Memorial Reef: Dive into history at this unique underwater memorial, honoring veterans while providing a vibrant marine habitat. The reef is ideal for snorkeling and diving, offering a chance to explore rich marine life and learn about its historical significance.

Best time to go to Panacea

The best time to visit Panacea is dependent on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are average and weather is mostly sunny. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January53.6°F (12.0°C)Light RainMostly SunnyAverageSlightly Low
February57.6°F (14.2°C)Light RainMostly SunnyAverageAverage
March62.4°F (16.9°C)Light RainMostly SunnyAverageAverage
April68.2°F (20.1°C)Light RainMostly SunnyModerately HighAverage
May74.8°F (23.8°C)Light RainMostly SunnyAverageSlightly High
June80.4°F (26.9°C)Moderate RainMostly SunnyModerately HighAverage
July81.7°F (27.6°C)Moderate RainMostly SunnyModerately HighSlightly Low
August81.7°F (27.6°C)Moderate RainMostly SunnyAverageAverage
September78.4°F (25.8°C)Light RainMostly SunnyAverageSlightly High
October71.1°F (21.7°C)Light RainMostly SunnyModerately LowSlightly High
November61.9°F (16.6°C)Light RainMostly SunnyModerately LowAverage
December57.6°F (14.2°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to Panacea

If you're planning to visit Panacea, Florida, the nearest major airport is Tallahassee International Airport (TLH), located 26 miles away. Several excellent hotel options are available near the airport, including the 4-star DoubleTree by Hilton Hotel Tallahassee and Hotel Duval, Autograph Collection, both about 5 miles from TLH. Transport services to the airport are conveniently offered by these hotels. Additionally, the 3.5-star Hotel Indigo Tallahassee - Collegetown by IHG is situated 4 miles from the airport. These accommodations provide easy access to transportation, making your arrival and departure seamless during your visit to Panacea.

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Explore a world of travel with Expedia

Frequently asked questions

What are the best budget hotels in Panacea?
The Panacea Motel is a fantastic budget-friendly option in Panacea, Florida, with an excellent review rating of 9.0 from guests. This charming motel offers a range of amenities that cater to both families and pet owners alike. With the convenience of free self-parking and complimentary in-room WiFi, guests can easily stay connected and explore the area without worrying about extra costs. View all budget hotels in Panacea.
When is the best time to go to Panacea?
The most popular time to visit Panacea is June, when the region comes alive with vibrant energy and the weather is pleasantly warm. Average temperatures during this month typically range from the mid-70s to low 80s Fahrenheit, making it great for outdoor activities and leisurely strolls along the scenic coastline.

From April to June, Panacea experiences its peak season, attracting visitors eager to explore its stunning natural beauty and enjoy an array of water-based activities. During this period, you'll find various festivals and local events that showcase the culture and hospitality of the area, providing a great opportunity to immerse yourself in the community.

For those who appreciate attentive service and premium experiences, June offers a delightful balance of comfortable weather and engaging outdoor adventures. Whether you're kayaking through crystal-clear waters or enjoying a sunset dinner at a seaside restaurant, the options are plentiful. Plus, the long daylight hours allow for extended exploration without the worry of rushing through your itinerary.

If you're considering a more budget-friendly option, November may be a good choice. While the temperatures are cooler, dipping into the 60s Fahrenheit, you can still enjoy a quieter experience with fewer crowds. This time of year allows for a more relaxed pace, great for those looking to unwind and savor the tranquil beauty of Panacea.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Panacea.
How can I save on a Panacea hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Panacea hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Panacea hotel?
Prices for hotels in Panacea often vary, but you can find a great deal from $77 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.