Tzantizotz Nature Reserve is a protected spot where you can see wildlife in their natural surroundings. Learn about the preservation efforts while enjoying the outdoors.

This nature reserve is on the to-do lists of many travelers to Santa Cruz La Laguna. But Tzantizotz Nature Reserve isn't the only drawcard in the area. Panajachel Municipal Market, Multiple Use Area Lake Atitlan Basin, and Church of Saint Peter are some other interesting sights close by.

Plan a trip to see Tzantizotz Nature Reserve

Price found within the past 48 hours. Click for updated prices.

Aviva Hotel

Save 100% on your flight

$722

per person

Nov 13 - Nov 17

found 20 hours ago

Roundtrip non-stop flight included

New York (JFK) to Guatemala City (GUA)

9.8/10 Exceptional! (13 reviews)

This hotel is fairly new so alot of construction is still happening and the road leading to the property is a bit rough. However, the staff is so pleasant and helpful. Breakfast was delicious my entire stay and the hotel is very clean, rooms are also spacious. The bed was huge but way too hard for my liking so made it a bit uncomfortable. Also the restaurant on site is brea

Reviewed on Sep 3, 2025

Hotel Soleil La Antigua

$1,254

per person

Dec 6 - Dec 13

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Guatemala City (GUA)

8.6/10 Excellent! (1,004 reviews)

All staff are nice, excellent service, good price, good location. The people of Guatemala are very kind!!!

Reviewed on Sep 26, 2025

Villas La Mar

Save 100% on your flight

$779

per person

Oct 30 - Nov 2

found 1 day ago

Roundtrip flight included

Fort Lauderdale (FLL) to Guatemala City (GUA)

8.2/10 Very Good! (138 reviews)

El lugar es muy bonito, ahora la propiedad está algo descuidada, se observa poco mantenimiento en el mobiliario cercano a la piscina o la terraza y la refrigeradora. Y en cuanto apoyo por medio del chat del app de expedía es nulo, el personal del lugar no atiende por el app, sino solicita que se llame a recepción en horario donde está disponible la recepción, en mi estadía tuve un inconveniente que me costó contactar alguien que me apoyara, finalmente se solventó y fue esperando al personal de la recepción. Ahora el lugar cuenta con una cocina, si en caso no se desea cocinar hay un restaurante que lo sugiero si se bebe alcohol es rápido ahora si es por comida tener paciencia para esperar.

Reviewed on Sep 16, 2025

Browse tours and tickets to explore Tzantizotz Nature Reserve

Tours & day trips

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Lake Atitlan One Day Tour from Antigua

Free cancellation available

Private & custom tours

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Sunrise Hike Tour on Indian's Nose Mountain

Free cancellation available

Food, drink & nightlife

See all 5 activities

From Antigua: Lake Atitlan Boat Trip with Maya Villages Tour

Free cancellation available

Popular places to visit

Azul Maya Archaeological Museum

Browse a private collection of Maya artifacts, such as jewelry and pottery, amassed by a local man during his travels throughout Guatemala.

Lake Atitlan showing landscape views, a lake or waterhole and a sunset

Lake Atitlán

Mountainous treks, artistic pursuits and scuba diving; the towns, villages and volcanoes that surround this picturesque lake in Guatemala's highlands offer adventure and culture.

Church of Saint Francis

Admire the art and architecture of the old Catholic church in Panajachel that is dedicated to the town’s patron saint.

Panajachel Municipal Market

Experience some of Guatemala’s indigenous traditions as you browse the stalls of this colorful market and shop for handcrafted souvenirs and fresh produce.

Church of Saint Peter

Visit a European-style church that enthralls with its impressive façade. The attractive parkland on its doorstep contains a striking statue of St.Peter.