South San Francisco Vacations from $389

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Your South San Francisco Vacation

Lock in a South San Francisco vacation package and get ready to experience the best of this lively city. Consider basing yourself in the neighborhood of Sharp Park, which is great for families, nature and golfing. Make your trip to South San Francisco even more fun by including some sightseeing. San Francisco State University, Cow Palace and Pacifica State Beach are among the major attractions worth exploring. Browse Expedia's wide range of travel options and start organizing your ideal vacation to South San Francisco now.

The Latest South San Francisco vacation packages

Price found within the past 48 hours. Click for updated prices.
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
Save 100% on your flight
Price was $646, price is now $389 per person
$389
per person
Oct 1 - Oct 5
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9/10 Wonderful! (4,487 reviews)
The location was great for what we wanted to see and do. The hotel is dated but clean and comfortable. The pillows could use an upgrade but otherwise we slept comfortably. Staff was nice.

Reviewed on Aug 23, 2025

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
Price was $782, price is now $486 per person
$486
per person
Oct 29 - Nov 2
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9/10 Wonderful! (6,695 reviews)
Our stay at the RIU was better than we had planned. Great location, wonderful and very helpful staff!!! Breakfast is amazing too! We would definitely stay again.

Reviewed on Aug 23, 2025

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $1,776, price is now $1,152 per person
$1,152
per person
Oct 9 - Oct 13
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9.2/10 Wonderful! (440 reviews)
I really enjoyed my stay at 1 Hotel San Francisco. The property is chic, stylish, and perfectly located close to the water with STK conveniently right across the street. The hotel feels thoughtfully designed, ergonomically friendly, and incredibly comfortable. One of the best parts for me was how pet-friendly it is—without any extra charges or hidden fees. They even provided my puppy with a cozy bed and dishes, which was such a thoughtful touch. While it is definitely on the pricier side, the experience is absolutely worth it—I would definitely stay here again with no hesitation.

Reviewed on Aug 16, 2025

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
Price was $869, price is now $568 per person
$568
per person
Oct 29 - Nov 2
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9.2/10 Wonderful! (1,437 reviews)
Very dated hotel rooms. Not what the pictures portray. However they are big rooms. Smoking must be allowed in some? Housekeeping were knocking on doors early and leaving trolleys and bags of rubbish through the narrow halls. Lifts are slow. The best part of this place was the concierge and we didn’t even have a car. Be mindful when booking the photos and description are not what you will get. The reviews seem to be skewed.

Reviewed on Aug 22, 2025

Treehouse Hotel Silicon Valley

Treehouse Hotel Silicon Valley

5 out of 5
Save 100% on your flight
Price was $1,040, price is now $690 per person
$690
per person
Sep 26 - Sep 29
found 2 hours ago
Roundtrip flight included
Seattle (SEA) to San Francisco (SFO)
9.8/10 Exceptional! (30 reviews)
Extremely detailed organized room. Excellent home like decor in the room. Awesome room condition, very big spacious and clean bathroom and soaking bath.

Reviewed on Aug 8, 2025

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Where to stay in South San Francisco

Find the best South San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about South San Francisco
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The East Side

2 out of top 10 points of interest in this area
3.5/5(956 area reviews)

If you're spending some time in The East Side, San Francisco Bay and San Bruno Point Park are top sights worth seeing.

Find hotels in The East Side

Discover the most popular places to visit in South San Francisco

Golden Gate Park featuring a garden and flowers

Golden Gate Park

This beloved park offers relaxation among trees, flowers and wildlife, right in San Francisco’s backyard.

Golden Gate Park
Pier 39 which includes a city, signage and street scenes

Pier 39

This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

Pier 39
Golden Gate Bridge illuminated at night with city lights in the background in California, USA

Golden Gate Bridge

Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.

Golden Gate Bridge

What to do in South San Francisco

Muir Woods and Sausalito Tour

Muir Woods and Sausalito Tour (Ferry & Bike Options Available)

$84
per adult
88% of travellers recommend
Muir Woods and Sausalito Tour (Ferry & Bike Options Available)
Alcatraz San Francisco Bay Cruise with Night Option

Alcatraz Visit with Night Option and SF Bay Cruise

$139
per adult
92% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
San Francisco GoCar Tour

GoCar San Francisco Tour

$99
per traveler
96% of travellers recommend
GoCar San Francisco Tour
See all activities in South San Francisco

South San Francisco Hotel Deals

Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront

3 out of 5
1300 Veterans Blvd, South San Francisco, CA
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $131 total per night from Aug 31 to Sep 1
$131 total
Aug 31 - Sep 1
Total with taxes and fees
8.4/10 Very Good! (1,645 reviews)
Oy
"Extremely walkable and good places close by to eat or drink a cup of coffee. Slept like a baby during my stay. The staff were helpful and professional! Parking was free and secure. Definitely a great option when staying in San Francisco"

Reviewed on Aug 22, 2025

Sonesta Select San Francisco Airport Oyster Point Waterfront
DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd

4 out of 5
275 S Airport Blvd, South San Francisco, CA
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $145 total per night from Sep 1 to Sep 2
$145 total
Sep 1 - Sep 2
Total with taxes and fees
8.4/10 Very Good! (1,828 reviews)
"The staff are great. Bar is a nice little spot. Good value."

Reviewed on Aug 19, 2025

DoubleTree by Hilton San Francisco South Airport Blvd
La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd, South San Francisco, CA
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $148 total per night from Sep 1 to Sep 2
$148 total
Sep 1 - Sep 2
Total with taxes and fees
8/10 Very Good! (2,021 reviews)
"I think everything was fine - except we had to go down everyday for new key cards - they stopped working and we picked this hotel because of pool and was closed for maintenance - wish I knew before"

Reviewed on Aug 20, 2025

La Quinta Inn & Suites by Wyndham San Francisco Airport N
See all 5,003 properties in South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a South San Francisco vacation package cost?
You can grab a vacation package to this destination from $389 on Expedia. However, how much your vacation to South San Francisco costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to South San Francisco?
You're likely to find reduced prices and better availability in February, October and December. Check out our cheap South San Francisco vacation packages and you could land some great off-season discounts.
How many days is enough for South San Francisco?
With a well-organized itinerary, you can easily tick off the top South San Francisco attractions in a few days. But if you'd like to explore off the beaten track or go on day tours, think about booking your South San Francisco vacation for longer.
Is it worth booking a vacation package to South San Francisco?
It's no wonder a South San Francisco vacation is on the must-do list of many travelers. Well-known attractions like K1 Speed San Francisco are just the beginning of what you can explore here.
How to find the best South San Francisco package deals?
Finding a cheap South San Francisco package deal is a breeze with Expedia. Once you've entered your preferred dates and destination under our "Packages" tab, set your budget range, apply a few filters and browse what's available. You can tailor your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most pocket-friendly South San Francisco package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are generally lower.
Is it cheaper to book a South San Francisco vacation as a package?
You can enjoy significant savings on your next South San Francisco retreat by booking a tailored vacation package. Check the "Package" heading, then select your destination and travel dates to browse the best hotel and flight prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to South San Francisco?
Enjoy fantastic discounts by reserving your flights early with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu South San Francisco adventure.
How to plan a trip to South San Francisco?

  1. Choose your dates: What you'd like to do in South San Francisco and your favorite season can help you decide when to travel.
  2. Set a budget: Factor in expenses like flights, transportation and food when calculating how much to set aside for your trip to South San Francisco. Then, choose a hotel that fits your budget, whether that's an economical stay or a deluxe getaway.
  3. Organize your South San Francisco getaway with our trip planning tool: Look for and book stays and experiences all in one place. You can also collaborate with your group to plan an unforgettable trip to South San Francisco together.
  4. Determine how many days away: Start by compiling a list of the sights and activities you want to get to in South San Francisco. Then, estimate how long you'll need at each, including any travel time.
  5. Combine your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to pick a South San Francisco vacation package that brings all your bookings together.
  6. Book any excursions or activities: Now to the fun part — locking in everything you want to see and do. Explore some of the best things to do in South San Francisco in South San Francisco and book your tickets in advance to save time (and maybe some money too!).

Does Expedia offer Book Now, Pay Later South San Francisco vacation packages?
If you're anything like us, you love traveling but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the overall cost of your South San Francisco trip across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up great vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.