Find hotels in Santa Maria, Guayaquil from $32

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Discover 389 Santa Maria hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Wyndham Garden Guayaquil
Rooftop bar, alfresco dining, open daily

Wyndham Garden Guayaquil

3.5 star property
9.0 out of 10, Wonderful, (1000)
"Very nice place, clean, kind staff, good location "
$80 nightly
The price is $90
Sep 14 - Sep 15
Wyndham Garden Guayaquil
Sheraton Guayaquil Hotel
2 restaurants, breakfast, lunch, dinner served; Regional cuisine

Sheraton Guayaquil Hotel

5.0 star property
9.0 out of 10, Wonderful, (580)
"Excellent service from the staff and just seven minutes away from the airport. "
$133 nightly
The price is $148
Sep 14 - Sep 15
Sheraton Guayaquil Hotel
Holiday Inn Guayaquil Airport by IHG
Outdoor pool

Holiday Inn Guayaquil Airport by IHG

3.5 star property
9.2 out of 10, Wonderful, (1011)
"Very nice hotel and close to the airport."
$101 nightly
The price is $114
Sep 28 - Sep 29
Holiday Inn Guayaquil Airport by IHG
Radisson Hotel Guayaquil
Outdoor pool, sun loungers

Radisson Hotel Guayaquil

5.0 star property
9.2 out of 10, Wonderful, (604)
"For the price very good and we will come back to stay here. FYI Close to the mall and location is very good. No breakfast is included on the price. "
$76 nightly
The price is $86
Sep 14 - Sep 15
Radisson Hotel Guayaquil
Hotel Patrimonial by Greenfield
Outdoor pool, sun loungers

Hotel Patrimonial by Greenfield

3.5 star property
8.6 out of 10, Excellent, (122)
"Friendly staff. I got moved to a more convenient room with no issues."
Hotel Patrimonial by Greenfield
DC Suites Aeropuerto
Lobby

DC Suites Aeropuerto

3.0 star property
9.0 out of 10, Wonderful, (552)
"Staff was very friendly and had a quick check-in. Loved the cat in the lobby."
$35 nightly
The price is $36
Sep 6 - Sep 7
DC Suites Aeropuerto
TRYP by Wyndham Guayaquil Airport
Exterior

TRYP by Wyndham Guayaquil Airport

4.5 star property
8.8 out of 10, Excellent, (1000)
"Everything was great"
$105 nightly
The price is $118
Sep 6 - Sep 7
TRYP by Wyndham Guayaquil Airport
Grand Hotel Guayaquil, an Ascend Collection Hotel
Outdoor pool, open 8:00 AM to 9:00 PM, sun loungers

Grand Hotel Guayaquil, an Ascend Collection Hotel

4.0 star property
9.2 out of 10, Wonderful, (941)
"The hotel and staff were great. "
$68 nightly
The price is $76
Sep 19 - Sep 20
Grand Hotel Guayaquil, an Ascend Collection Hotel
Iguanazu Bed & Breakfast
Exterior

Iguanazu Bed & Breakfast

3.5 star property
9.2 out of 10, Wonderful, (46)
"Swimming pool"
$89 nightly
The price is $102
Sep 15 - Sep 16
Iguanazu Bed & Breakfast
Hotel GH Galeria
Exterior

Hotel GH Galeria

3.5 star property
8.4 out of 10, Very Good, (385)
"Location "
$61 nightly
The price is $69
Sep 6 - Sep 7
Hotel GH Galeria
Unipark by Oro Verde Hotels
Reception

Unipark by Oro Verde Hotels

4.0 star property
9.2 out of 10, Wonderful, (1000)
"Updated building recently bought by oro verde hotels group Great breakfast!"
$70 nightly
The price is $80
Sep 27 - Sep 28
Unipark by Oro Verde Hotels
Hotel Puerto Pacifico Guayaquil Airport
Massages

Hotel Puerto Pacifico Guayaquil Airport

4.0 star property
8.8 out of 10, Excellent, (206)
"Nice staff - clean & modern facilities & good breakfast buffet (& included w my booking)."
$49 nightly
The price is $51
Sep 6 - Sep 7
Hotel Puerto Pacifico Guayaquil Airport
Ibis Styles El Malecon Guayaquil
Exterior

Ibis Styles El Malecon Guayaquil

4.0 star property
9.4 out of 10, Exceptional, (238)
"This hotel is a good value for your money..."
$60 nightly
The price is $68
Sep 6 - Sep 7
Ibis Styles El Malecon Guayaquil
Courtyard by Marriott Guayaquil
Lobby

Courtyard by Marriott Guayaquil

3.5 star property
9.0 out of 10, Wonderful, (1001)
"Great stay "
$76 nightly
The price is $85
Oct 3 - Oct 4
Courtyard by Marriott Guayaquil
Hotel Palace Guayaquil
Lobby

Hotel Palace Guayaquil

4.0 star property
9.2 out of 10, Wonderful, (898)
"Good place to stay "
$63 nightly
The price is $71
Oct 4 - Oct 5
Hotel Palace Guayaquil
Wyndham Guayaquil Puerto Santa Ana
Presidential Suite, 1 King Bed, Jetted Tub, River View | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Wyndham Guayaquil Puerto Santa Ana

4.5 star property
9.2 out of 10, Wonderful, (1014)
"Nice place, friendly staff and safe to walk around!!"
$110 nightly
The price is $123
Sep 14 - Sep 15
Wyndham Guayaquil Puerto Santa Ana
Oro Verde Guayaquil
Children's activities

Oro Verde Guayaquil

5.0 star property
9.4 out of 10, Exceptional, (1000)
"Is a great place to stay "
$99 nightly
The price is $111
Sep 14 - Sep 15
Oro Verde Guayaquil
Luxva Hotel Boutique
Exterior

Luxva Hotel Boutique

3.0 star property
9.4 out of 10, Exceptional, (159)
"Friendly staff. "
$60 nightly
The price is $61
Oct 3 - Oct 4
Luxva Hotel Boutique
Hilton Colon Guayaquil
Lobby

Hilton Colon Guayaquil

4.5 star property
8.6 out of 10, Excellent, (761)
"Really nice hotel and staff."
$98 nightly
The price is $110
Sep 15 - Sep 16
Hilton Colon Guayaquil
Suitesecu Guayaquil
Executive Suite, Kitchenette, City View | Private kitchen | Microwave, electric kettle, griddle, cookware/dishes/utensils

Suitesecu Guayaquil

4.5 star property
9.6 out of 10, Exceptional, (5)
"Great place! Close to everything. Fast host. "
$30 nightly
The price is $32
Sep 8 - Sep 9
Suitesecu Guayaquil
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and La Perla while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

Kennedy

1 out of top 10 points of interest in this area

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.

Top Santa Maria Hotel Reviews

Hotel GH Galeria

Hotel GH Galeria

10/10 Excellent
"It’s 10 m from the airport, the Area is not that great for the price."
Lissette 3-night trip
Posted 3 days ago
Hotel GH Galeria

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Maria.
How can I save on a Santa Maria hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Santa Maria hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Maria hotel?
Hotel prices in Santa Maria often vary, but you can find a great deal from $32 on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.