Find spa resorts & hotels in Twin Oaks, St. Louis from $153

Start date: Check-in selected.
To Date
End date: Check-out

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Twin Oaks Resorts & Hotels with Spas

Tonight
Dec 6 - Dec 7
Tomorrow
Dec 7 - Dec 8
Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21

Top Twin Oaks Resorts & Hotels with Spas

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 star property
St. Charles
8.4 out of 10, Very Good, (1000)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
$166 nightly
The price is $194
Dec 7 - Dec 8
Total with taxes and fees
Ameristar Casino Resort and Spa
Massages
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1482)
"Great staff and clean room"
United States
Chris
$131 nightly
The price is $153
Dec 28 - Dec 29
Total with taxes and fees
21C Museum Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1002)
"The staff was amazing. The bed was so comfortable. "
United States
Mary
$415 nightly
The price is $485
Jan 1 - Jan 2, 2026
Total with taxes and fees
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5.0 star property
Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
$499 nightly
The price is $583
Dec 21 - Dec 22
Total with taxes and fees
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Twin Oaks Hotel Reviews

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"Clean Room, the view was amazing, the game room was perfect to help calm my daughter the morning of her procedure at the Children’s Hospital. "
Shane 1-night trip
Posted 22 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Frequently asked questions

Looking to vacation at a spa hotel in Twin Oaks?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Spa hotels are a great way to break away from your daily routine and add a layer of luxury to your weekend away.
What's there to see and do in Twin Oaks?
Experience all that Twin Oaks has to offer when you visit Museum of Transportation, Magic House - St. Louis Children's Museum, and Bellerive Country Club. If you have a little extra time during your trip, you might want to make a stop at Route 66 State Park and Grant's Farm.
What is a Twin Oaks spa hotel?
Spa hotels in Twin Oaks have full on-site spas which offer services such as couples massages and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.

Explore a world of travel with Expedia