Name: 21C Museum Hotel St Louis
Price range: $173 total
Rating: 9

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO

$127 nightly

$149 total

May 25 - May 26

Total with taxes and fees

Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...

8.6/10 Excellent! (4,053 reviews)

The breakfast buffet was pricey, but good.

Reviewed on May 6, 2026

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO

$105 nightly

$122 total

May 17 - May 18

Total with taxes and fees

Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...

8.8/10 Excellent! (3,188 reviews)

Everything was great staff was excellent

Reviewed on May 5, 2026

21C Museum Hotel St Louis

1528 Locust street St. Louis MO

$148 nightly

$173 total

May 31 - Jun 1

Total with taxes and fees

Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...

9/10 Wonderful! (1,819 reviews)

All the restaurants and bar were excellent.

Reviewed on May 4, 2026

See all 1,913 properties in Des Peres

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

White House at Grand Central

3805 Lindell Blvd St. Louis MO

Stay at this apartment in St. Louis. Enjoy free WiFi, a 24-hour front desk, and a garden. Popular attractions St. Louis Union Station and Busch Stadium are located ...

8.4/10 Very Good! (131 reviews)

Room smelled of cigarettes, had to leave and book another property, check in and location was awful and hard to find. Property is nothing like it is described in booking. Bed was comfortable for the one night I stayed

Reviewed on Apr 25, 2026

Landing Furnished Apartments - Central West End

4050 W Pine Blvd St. Louis MO

Book a stay at this business-friendly apartment in St. Louis. Enjoy free WiFi, an outdoor pool, and a 24-hour fitness center. Popular attractions St. Louis Union ...

9/10 Wonderful! (2 reviews)

The apartment was clean and looked exactly like the photos. Check in was easy. I was unable to use the app I believe because I used a 3rd party to book. There were no instructions about the property and I did get locked in the courtyard at one point. Also check it was unclear because I could not ...

Reviewed on May 3, 2026

4BR 2BA Modern Family Home with Private Heated Inground Pool Open March 1-Nov11

St. Louis MO

Book a stay at this family-friendly vacation home in St. Louis. Enjoy private pools, a garden, and laundry facilities. Popular attractions St. Louis Zoo and ...

10/10 Exceptional! (189 reviews)

Wow! When the host asked about the ages of the kids I was bringing, I had no idea she was going to set up age appropriate toys for them! What a thoughtful gesture! I also appreciated the ample table space for a whole family to eat together, which is so often lacking in a rental house. I was able ...

Reviewed on Apr 7, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Busch Stadium

4.5/5(1,487 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

St. Louis Union Station

4/5(625 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

Gateway Arch

4.5/5(2,542 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

St. Louis Zoo

4.5/5(1,225 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

Forest Park

4.5/5(1,059 reviews)

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.