$164 Cheap American Airlines flights Miami (MIA) to Knoxville (TYS)

Make use of the "Price (lowest to highest)" filter on Expedia to search for cheap American Airlines return flights from $159 from MIA to TYS. Affordable one-way options from $164 are available as well.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for cheap American Airlines flights from Miami Intl. Airport (MIA) to McGhee Tyson Airport (TYS) one to three months before your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and itinerary, the ideal day to book a domestic flight is generally Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The first American Airlines flight from MIA to TYS takes off at 8:05PM UTC-5, landing at 10:23PM UTC-5. If you prefer to head off later in the day, the last American Airlines flight leaves MIA at 8:05PM UTC-5 and touches down at TYS at 10:23PM UTC-5. Flying early is often a good option as morning flights are less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.