Cheap American Airlines flights Vigo (VGO) to Knoxville (TYS)

Scoring cheap one-way American Airlines flights from VGO to TYS on Expedia couldn't be easier — just filter by "Price (lowest to highest)." Alternatively, check out our affordable round-trip fares for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Snagging the best American Airlines deals from VGO to TYS often comes down to timing. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. Better yet, you can pocket 17% on average by buying your tickets on a Sunday compared to a Friday, which is often the most expensive day to book.* It's a good idea to start searching for flights about one month before your travel dates.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Morning" and "Early Morning" to find the earliest departures from VGO to TYS. Taking off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.