Cheap Spirit Airlines flights Medellín (MDE) to San Diego (SAN)

Set the "Price (lowest to highest)" filter on Expedia to search for cheap Spirit Airlines round-trip flights from MDE to SAN. Affordable one-way fares are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for Spirit Airlines flights from MDE to SAN about one month before you want to leave. The most affordable time to book an international flight is usually 18 to 29 days ahead of your travel date when you can save 17% versus booking four to five months in advance. No matter your itinerary and fare class, the best day to book international airfare is usually Sunday. Friday can be the most expensive. Travelers who book on a Sunday can save 17% on average compared to those who book on a Friday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Find Spirit Airlines's earliest flights from MDE to SAN by selecting the "Morning" and "Early Morning" filters. Not only will you arrive at your destination sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Journey from MDE to SAN with Spirit Airlines and enjoy a host of benefits starting with a rewarding loyalty program. When booking through Expedia as a Free Spirit and One Key™ member, you may also earn OneKeyCash™* to use on select future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.