Photo by Karla Hernandez

Find hotels in Middletown, San Diego

Start date: Check-in selected.
To Date
End date: Check-out

Check prices for these dates

Tonight
Nov 21 - Nov 22
Tomorrow
Nov 22 - Nov 23
This weekend
Nov 21 - Nov 23
Next weekend
Nov 28 - Nov 30

Filter by

Guest rating
Guest rating
Star rating

Discover Middletown hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills

4.5 star property
Middletown
9.6 out of 10, Exceptional, (101)
"Staff was very attentive and the building was wonderful. The only reason I didn't rate 5 stars is it can be quite loud being across the street from the airport. "
United States
Michael
$148 nightly
The price is $167
Dec 8 - Dec 9
Total with taxes and fees
City24 Hotel Little Italy Mission Hills
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
1.4 mi from Middletown
8.4 out of 10, Very Good, (6049)
"I enjoyed my stay."
United States
Kevin
$160 nightly
The price is $186
Nov 23 - Nov 24
Total with taxes and fees
Wyndham San Diego Bayside
Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 2.4 mi from Middletown
9.0 out of 10, Wonderful, (3089)
"Our stay was great! Would stay here again"
United States
Carla
$307 nightly
The price is $355
Nov 27 - Nov 28
Total with taxes and fees
Hard Rock Hotel San Diego
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 star property
6.7 mi from Middletown
9.2 out of 10, Wonderful, (3425)
"Clean, staff friendly, great place for a stay"
United States
Derrick
$107 nightly
The price is $118
Nov 30 - Dec 1
Total with taxes and fees
Best Western Plus Marina Gateway Hotel
Rooftop terrace
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 2 mi from Middletown
8.6 out of 10, Excellent, (2040)
"staff was very friendly and hotel was clean"
United States
Stephany
$105 nightly
The price is $122
Nov 23 - Nov 24
Total with taxes and fees
Palihotel San Diego Gaslamp Quarter
Serves dinner and happy hour
The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
2.2 mi from Middletown
9.0 out of 10, Wonderful, (2658)
"Beautiful and historic, very comfortable. Would definitely stay there again. "
United States
Amy
$144 nightly
The price is $167
Nov 27 - Nov 28
Total with taxes and fees
The Horton Grand, Downtown/Gaslamp Quarter
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 2.3 mi from Middletown
9.0 out of 10, Wonderful, (1215)
"Very friendly staff!"
United States
Glenn
$127 nightly
The price is $147
Nov 23 - Nov 24
Total with taxes and fees
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 1.9 mi from Middletown
9.0 out of 10, Wonderful, (1006)
"Great room, clean, spacious and quiet. "
United States
Maria
$99 nightly
The price is $113
Nov 23 - Nov 24
Total with taxes and fees
Gaslamp Plaza Suites
Property entrance
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 star property
1.8 mi from Middletown
8.6 out of 10, Excellent, (1429)
"Great stay, clean room. Staff was very friendly as well. Would stay again. "
United States
Alexis
$111 nightly
The price is $129
Dec 22 - Dec 23
Total with taxes and fees
The Bristol Hotel San Diego
Front of property
The Sofia Hotel

The Sofia Hotel

3.5 star property
1.8 mi from Middletown
8.4 out of 10, Very Good, (1631)
"Excellent stay all-around!"
United States
Nalani
$138 nightly
The price is $160
Dec 16 - Dec 17
Total with taxes and fees
The Sofia Hotel
Presidential Suite, 2 Bedrooms, Non Smoking | Living room | 36-inch LCD TV with digital channels, TV, pay movies
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
1.8 mi from Middletown
9.0 out of 10, Wonderful, (849)
"Lovely hotel. Really enjoyed the complimentary bottle of wine as well as how convenient it was to walk to restaurants & bars . "
United States
Gisselle
$146 nightly
The price is $170
Nov 23 - Nov 24
Total with taxes and fees
Alma San Diego Downtown, a Tribute Portfolio Hotel
Premium bedding, pillowtop beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 2.2 mi from Middletown
9.4 out of 10, Exceptional, (1001)
"The room was immaculate, the staff were helpful and friendly and our stay was so wonderful. "
United States
Samantha Erin
$125 nightly
The price is $145
Nov 23 - Nov 24
Total with taxes and fees
Staypineapple, Hotel Z, Gaslamp San Diego
Garden
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4.0 star property
1.4 mi from Middletown
9.2 out of 10, Wonderful, (2952)
"Great stay"
United States
Songkwon
$125 nightly
The price is $144
Nov 24 - Nov 25
Total with taxes and fees
Legacy Resort Hotel & Spa
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4.0 star property
2.2 mi from Middletown
9.2 out of 10, Wonderful, (1922)
"Great hotel"
United States
Farzana
$204 nightly
The price is $237
Nov 28 - Nov 29
Total with taxes and fees
Marriott Marquis San Diego Marina
Exterior
La Pensione Hotel

La Pensione Hotel

3.0 star property
Little Italy, 1.2 mi from Middletown
8.6 out of 10, Excellent, (1908)
"Friendly staff, very nice room, great location!"
United States
Lisa
$137 nightly
The price is $156
Nov 27 - Nov 28
Total with taxes and fees
La Pensione Hotel
Check-in/check-out kiosk
Urban Boutique Hotel

Urban Boutique Hotel

3.0 star property
Little Italy, 1.3 mi from Middletown
8.6 out of 10, Excellent, (1279)
"Alwsys clean , great staff andvperfect location"
United States
Colleen
$120 nightly
The price is $136
Nov 27 - Nov 28
Total with taxes and fees
Urban Boutique Hotel
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillowtop beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
1.4 mi from Middletown
8.8 out of 10, Excellent, (665)
"Great staff, great location, great value. "
United States
Juan
$90 nightly
The price is $104
Dec 14 - Dec 15
Total with taxes and fees
The DEXTRO Little Italy, BW Premier Collection
Front of property
Hotel Palmeras Chula Vista

Hotel Palmeras Chula Vista

2.0 star property
8.4 mi from Middletown
7.2 out of 10, Good, (1959)
"Good hotel. "
United States
Leonel
$64 nightly
The price is $70
Nov 23 - Nov 24
Total with taxes and fees
Hotel Palmeras Chula Vista
Exterior
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 star property
3.3 mi from Middletown
9.2 out of 10, Wonderful, (3130)
"Great staff and beautiful location. "
United States
elaine
$129 nightly
The price is $148
Nov 23 - Nov 24
Total with taxes and fees
Bay Club Hotel & Marina
Exterior
Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 2.3 mi from Middletown
9.0 out of 10, Wonderful, (1132)
"Great Hotel - good position and very helpful staff. "
United Kingdom
James
$190 nightly
The price is $220
Dec 22 - Dec 23
Total with taxes and fees
Margaritaville Hotel San Diego Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Middletown

Find the best Middletown areas and neighborhoods for the activities you enjoy most. Learn more about Middletown
Learn more about Middletown
US Grant Hotel

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Gaslamp Quarter showing signage, night scenes and street scenes

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Pacific Beach Park showing a beach

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Belmont Park showing rides and a garden

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Ocean Beach

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Middletown Hotel Reviews

Best Western Seven Seas

Best Western Seven Seas

10/10 Excellent
"Great hot tub"
Darren 1-night trip
Posted 22 hours ago
Best Western Seven Seas

Frequently asked questions

What are the best hotels in Middletown that travelers recommend?
City24 Hotel Little Italy Mission Hill is a great choice for travelers visiting San Diego, boasting a great rating of 9.6. This hotel offers a modern and inclusive setting, complete with a rooftop terrace and garden that provide stunning views of the city. Its spacious rooms feature premium bedding and convenient amenities like a kitchen, ensuring guests feel right at home whether they're here for leisure or business.
What are the best family hotels in Middletown?
City24 Hotel Little Italy Mission Hill is an excellent choice for families visiting San Diego, boasting a customer review rating of 9.6. This hotel is thoughtfully designed with family comfort in mind, featuring spacious rooms that include convenient amenities such as a sofa bed and a complimentary crib, ensuring a restful stay for parents and children alike.
What are the most romantic hotels in Middletown for couples?
For a romantic getaway, the City24 Hotel Little Italy Mission Hill in San Diego is a delightful choice, boasting an impressive review score of 9.6. This hotel offers an inclusive setting complemented by its rooftop garden and terrace, superb for couples looking to enjoy a serene moment together while soaking in the beautiful views.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Middletown hotel for you.
How can I save on a Middletown hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Middletown hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Middletown hotel?
Hotel prices in Middletown often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia