$398 Cheap Flights from Jacksonville (JAX) to La Crosse (LSE)

View $398 flight on Wed, Nov 12, 2025Opens in a new window

Popular airlines from Jacksonville International Airport (JAX) to La Crosse, WI (LSE-La Crosse Municipal)

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Cheap Flights from Jacksonville to La Crosse (JAX-LSE)

Prices were available within the past 7 days and start at $398 for one-way flights and $437 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Dec 31 - Sun, Jan 4
JAX
Jacksonville
LSE
La Crosse
$437 Roundtrip, found 1 day ago
$437
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Dec 31 from Jacksonville to La Crosse, returning Sun, Jan 4, priced at $437 found 1 day ago
American Airlines
Wed, Nov 26 - Tue, Dec 2
JAX
Jacksonville
LSE
La Crosse
$440 Roundtrip, found 5 days ago
$440
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Nov 26 from Jacksonville to La Crosse, returning Tue, Dec 2, priced at $440 found 5 days ago
American Airlines
Wed, Dec 31 - Sun, Jan 4
JAX
Jacksonville
LSE
La Crosse
$443 Roundtrip, found 1 day ago
$443
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Dec 31 from Jacksonville to La Crosse, returning Sun, Jan 4, priced at $443 found 1 day ago
American Airlines
Mon, Jan 12 - Mon, Jan 19
JAX
Jacksonville
LSE
La Crosse
$464 Roundtrip, found 5 days ago
$464
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Jan 12 from Jacksonville to La Crosse, returning Mon, Jan 19, priced at $464 found 5 days ago
American Airlines
Fri, Dec 26 - Thu, Jan 1
JAX
Jacksonville
LSE
La Crosse
$470 Roundtrip, found 2 days ago
$470
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Dec 26 from Jacksonville to La Crosse, returning Thu, Jan 1, priced at $470 found 2 days ago
American Airlines
Wed, Nov 26 - Tue, Dec 2
JAX
Jacksonville
LSE
La Crosse
$470 Roundtrip, found 3 days ago
$470
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Nov 26 from Jacksonville to La Crosse, returning Tue, Dec 2, priced at $470 found 3 days ago
American Airlines
Wed, Nov 26 - Tue, Dec 2
JAX
Jacksonville
LSE
La Crosse
$476 Roundtrip, found 3 days ago
$476
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Nov 26 from Jacksonville to La Crosse, returning Tue, Dec 2, priced at $476 found 3 days ago
American Airlines
Wed, Nov 26 - Tue, Dec 2
JAX
Jacksonville
LSE
La Crosse
$489 Roundtrip, found 5 days ago
$489
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Nov 26 from Jacksonville to La Crosse, returning Tue, Dec 2, priced at $489 found 5 days ago
American Airlines
Tue, Jan 20 - Tue, Feb 3
JAX
Jacksonville
LSE
La Crosse
$490 Roundtrip, found 5 days ago
$490
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Jan 20 from Jacksonville to La Crosse, returning Tue, Feb 3, priced at $490 found 5 days ago
American Airlines
Sat, Jan 24 - Tue, Feb 3
JAX
Jacksonville
LSE
La Crosse
$496 Roundtrip, found 5 days ago
$496
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jan 24 from Jacksonville to La Crosse, returning Tue, Feb 3, priced at $496 found 5 days ago

Frequently asked questions

How much does a flight from Jacksonville Intl. Airport (JAX) to La Crosse Municipal Airport (LSE) cost?
Snag a cheap one-way flight from $398 or cheap return flight from $437 from Jacksonville Intl. Airport (JAX) to La Crosse Municipal Airport (LSE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Jacksonville Intl. Airport (JAX) to La Crosse Municipal Airport (LSE)?
The cheapest month to fly from JAX to LSE is December, when there's less demand. Off-peak season is often when better flight deals are available between these airports.
What is the cheapest airline that flies from Jacksonville Intl. Airport (JAX) to La Crosse Municipal Airport (LSE)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find the carrier with the cheapest JAX to LSE flight.
How many flights per day from Jacksonville Intl. Airport (JAX) to La Crosse Municipal Airport (LSE)?
You'll have to hop on a flight with a layover if you're traveling from Jacksonville Intl. Airport (JAX) to La Crosse Municipal Airport (LSE). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from JAX to LSE?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jacksonville Intl. Airport (JAX) to La Crosse Municipal Airport (LSE)?
To reach La Crosse Municipal Airport (LSE) on schedule, select a flight that takes off from Jacksonville Intl. Airport (JAX) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jacksonville Intl. Airport (JAX) to La Crosse Municipal Airport (LSE) last-minute?
Last-minute bookings from JAX to LSE are usually more expensive. For the lowest prices, start searching for flights well ahead of time. That being said, if your travel plans are flexible, you may find a cheap ticket just before your departure.
Is it cheaper to book a JAX to LSE flight and hotel package?
Compared with arranging hotels and flights separately, booking a JAX to LSE flight and hotel package with Expedia could result in significant savings. Better still, having it all in one place takes the hassle out of planning your trip. Simply secure your flights and select from our wide range of stays, then tailor your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Jacksonville Intl. Airport (JAX) to La Crosse Municipal Airport (LSE)?
In most instances, you can reschedule or cancel your JAX to LSE flight. However, additional charges may apply, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you'd like more information, head to our Customer Service portal.

Travel information

Origin airport
Jacksonville Intl.
Destination airport
La Crosse Municipal
Airlines serving
American Airlines
Roundtrip price
$437
Distance
1062 mi

Book with confidence

Jacksonville to La Crosse Flights

The cheapest times to fly from Jacksonville to La Crosse

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Jacksonville to La Crosse are during the month of December. You can find some of the cheapest flights from Jacksonville to La Crosse with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Jacksonville to La Crosse

Sunday is one of the best days to book for cheap flights from Jacksonville to La Crosse: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Jacksonville to La Crosse

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Jacksonville to La Crosse in 2025. You can also book with separate airlines for your outbound and return journeys, from $398 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Jacksonville to La Crosse flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Jacksonville to La Crosse airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Jacksonville to La Crosse Flights

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*Available to One Key members.