$409 Cheap Flights from Medellín (MDE) to Panama City (ECP)

View $409 flight on Mon, Mar 16, 2026Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Northwest Florida Beaches Intl. Airport (ECP)

Cheap Flights from Medellín to Panama City (MDE-ECP)

Prices were available within the past 7 days and start at $409 for one-way flights and $750 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Thu, Oct 30 - Thu, Nov 6
MDE
Medellin
ECP
Panama City
$750 Roundtrip, found 2 days ago
$750
Roundtrip
found 2 days ago
Select United flight, departing Thu, Oct 30 from Medellin to Panama City, returning Thu, Nov 6, priced at $750 found 2 days ago
United
Fri, Oct 31 - Thu, Nov 6
MDE
Medellin
ECP
Panama City
$757 Roundtrip, found 2 days ago
$757
Roundtrip
found 2 days ago
Select United flight, departing Fri, Oct 31 from Medellin to Panama City, returning Thu, Nov 6, priced at $757 found 2 days ago
United
Thu, Oct 30 - Thu, Nov 6
MDE
Medellin
ECP
Panama City
$760 Roundtrip, found 2 days ago
$760
Roundtrip
found 2 days ago
Select United flight, departing Thu, Oct 30 from Medellin to Panama City, returning Thu, Nov 6, priced at $760 found 2 days ago
United
Thu, Oct 30 - Fri, Nov 7
MDE
Medellin
ECP
Panama City
$761 Roundtrip, found 2 days ago
$761
Roundtrip
found 2 days ago
Select United flight, departing Thu, Oct 30 from Medellin to Panama City, returning Fri, Nov 7, priced at $761 found 2 days ago
United
Thu, Oct 30 - Thu, Nov 6
MDE
Medellin
ECP
Panama City
$763 Roundtrip, found 2 days ago
$763
Roundtrip
found 2 days ago
Select United flight, departing Thu, Oct 30 from Medellin to Panama City, returning Thu, Nov 6, priced at $763 found 2 days ago
United
Fri, Oct 31 - Fri, Nov 7
MDE
Medellin
ECP
Panama City
$768 Roundtrip, found 2 days ago
$768
Roundtrip
found 2 days ago
Select United flight, departing Fri, Oct 31 from Medellin to Panama City, returning Fri, Nov 7, priced at $768 found 2 days ago
United
Thu, Oct 30 - Thu, Nov 6
MDE
Medellin
ECP
Panama City
$773 Roundtrip, found 2 days ago
$773
Roundtrip
found 2 days ago
Select United flight, departing Thu, Oct 30 from Medellin to Panama City, returning Thu, Nov 6, priced at $773 found 2 days ago
American Airlines
Thu, Oct 30 - Thu, Nov 6
MDE
Medellin
ECP
Panama City
$800 Roundtrip, found 2 days ago
$800
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Oct 30 from Medellin to Panama City, returning Thu, Nov 6, priced at $800 found 2 days ago
LATAM Airlines Group
Thu, Oct 30 - Thu, Nov 6
MDE
Medellin
ECP
Panama City
$840 Roundtrip, found 2 days ago
$840
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Thu, Oct 30 from Medellin to Panama City, returning Thu, Nov 6, priced at $840 found 2 days ago
Delta
Thu, Oct 30 - Thu, Nov 6
MDE
Medellin
ECP
Panama City
$897 Roundtrip, found 2 days ago
$897
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Oct 30 from Medellin to Panama City, returning Thu, Nov 6, priced at $897 found 2 days ago

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Northwest Florida Beaches Intl. ECP. Cheapest and Closest option available. Average driving time to city center is 35 minutes. Flights from $843
ECP
Northwest Florida Beaches Intl.
CheapestClosest
Average driving time to city center35 min
Flights from $843

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Get a cheap one-way flight from $409 or cheap return flight from $750 from Jose Maria Cordova Intl. Airport (MDE) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to Northwest Florida Beaches Intl. Airport (ECP)?
The cheapest month to fly from MDE to ECP is October, when demand is low. Off-peak months are often when airlines offer better prices between these airports.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to Northwest Florida Beaches Intl. Airport (ECP)?
To find the cheapest airline that'll fly you from MDE to ECP, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to Northwest Florida Beaches Intl. Airport (ECP)?
Direct flights from Jose Maria Cordova Intl. Airport (MDE) to Northwest Florida Beaches Intl. Airport (ECP) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MDE to ECP?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can change depending on a range of factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to Northwest Florida Beaches Intl. Airport (ECP)?
To avoid possible delays on the Jose Maria Cordova Intl. Airport (MDE) to Northwest Florida Beaches Intl. Airport (ECP) route, fly before 3 PM. Departures after this hour have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Holding off until just before your trip to book a ticket from MDE to ECP generally means paying more. While it's possible to find some last-minute discounts, they're not always guaranteed. Allow some flexibility in your schedule for the best chance of getting a bargain.
Is it cheaper to book a MDE to ECP flight and hotel package?
Opting for a MDE to ECP flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Select from our extensive range of stays and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to Northwest Florida Beaches Intl. Airport (ECP)?
If you reserved your MDE to ECP flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

Travel information

Origin airport
José María Córdova Intl.
Destination airport
Northwest Florida Beaches Intl.
Roundtrip price
$749
Distance
1801 mi

Book with confidence

Medellín to Panama City Flights

The cheapest times to fly from Medellín to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to Panama City are during the month of October. You can find some of the cheapest flights from Medellín to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to Panama City

Sunday is one of the best days to book for cheap flights from Medellín to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $409 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Medellín to Panama City Flights

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*Available to One Key members.