$100 Cheap Flights from Moline (MLI) to Panama City (ECP)

View $100 flight on Sat, Jan 17, 2026Opens in a new window

Popular airlines from Quad City Intl. Airport (MLI) to Northwest Florida Beaches Intl. Airport (ECP)

Cheap Flights from Moline to Panama City (MLI-ECP)

Prices were available within the past 7 days and start at $100 for one-way flights and $243 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Nov 27 - Thu, Dec 4
MLI
Moline
ECP
Panama City
$243 Roundtrip, found 4 days ago
$243
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Nov 27 from Moline to Panama City, returning Thu, Dec 4, priced at $243 found 4 days ago
Delta
Thu, Nov 27 - Wed, Dec 3
MLI
Moline
ECP
Panama City
$248 Roundtrip, found 4 days ago
$248
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Nov 27 from Moline to Panama City, returning Wed, Dec 3, priced at $248 found 4 days ago
American Airlines
Fri, Dec 12 - Tue, Dec 16
MLI
Moline
ECP
Panama City
$249 Roundtrip, found 4 hours ago
$249
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Fri, Dec 12 from Moline to Panama City, returning Tue, Dec 16, priced at $249 found 4 hours ago
United
Tue, Feb 10 - Sat, Feb 14
MLI
Moline
ECP
Panama City
$259 Roundtrip, found 6 days ago
$259
Roundtrip
found 6 days ago
Select United flight, departing Tue, Feb 10 from Moline to Panama City, returning Sat, Feb 14, priced at $259 found 6 days ago
Delta
Mon, Oct 6 - Wed, Oct 15
MLI
Moline
ECP
Panama City
$279 Roundtrip, found 2 days ago
$279
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Oct 6 from Moline to Panama City, returning Wed, Oct 15, priced at $279 found 2 days ago
Delta
Tue, Sep 30 - Thu, Oct 9
MLI
Moline
ECP
Panama City
$284 Roundtrip, found 6 days ago
$284
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Sep 30 from Moline to Panama City, returning Thu, Oct 9, priced at $284 found 6 days ago
Delta
Wed, Dec 24 - Tue, Jan 6
MLI
Moline
ECP
Panama City
$294 Roundtrip, found 6 days ago
$294
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Dec 24 from Moline to Panama City, returning Tue, Jan 6, priced at $294 found 6 days ago
Delta
Wed, Nov 19 - Wed, Nov 26
MLI
Moline
ECP
Panama City
$299 Roundtrip, found 1 day ago
$299
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Nov 19 from Moline to Panama City, returning Wed, Nov 26, priced at $299 found 1 day ago
United
Sat, Feb 21 - Thu, Mar 5
MLI
Moline
ECP
Panama City
$299 Roundtrip, found 6 days ago
$299
Roundtrip
found 6 days ago
Select United flight, departing Sat, Feb 21 from Moline to Panama City, returning Thu, Mar 5, priced at $299 found 6 days ago
Delta
Wed, Dec 10 - Tue, Dec 16
MLI
Moline
ECP
Panama City
$301 Roundtrip, found 6 days ago
$301
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Dec 10 from Moline to Panama City, returning Tue, Dec 16, priced at $301 found 6 days ago

Find the cheapest month to fly from Moline (MLI) to Panama City (ECP)

May is typically the cheapest month to fly

From $223 - $495 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Northwest Florida Beaches Intl. ECP. Cheapest and Closest option available. Average driving time to city center is 35 minutes. Flights from $294
ECP
Northwest Florida Beaches Intl.
CheapestClosest
Average driving time to city center35 min
Flights from $294

Frequently asked questions

How much does a flight from Quad City Intl. Airport (MLI) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Snag a cheap one-way flight from $100 or cheap return flight from $243 from Quad City Intl. Airport (MLI) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Quad City Intl. Airport (MLI) to Northwest Florida Beaches Intl. Airport (ECP)?
Traveling in November can help you save, as it's the cheapest month for flights between MLI and ECP. You'll usually find the lowest prices during off-peak months.
What is the cheapest airline that flies from Quad City Intl. Airport (MLI) to Northwest Florida Beaches Intl. Airport (ECP)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll take you from MLI to ECP. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Quad City Intl. Airport (MLI) to Northwest Florida Beaches Intl. Airport (ECP)?
You'll have to book a flight with a layover if you're traveling from Quad City Intl. Airport (MLI) to Northwest Florida Beaches Intl. Airport (ECP). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from MLI to ECP?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* However, this can vary based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Quad City Intl. Airport (MLI) to Northwest Florida Beaches Intl. Airport (ECP)?
To avoid possible delays on the Quad City Intl. Airport (MLI) to Northwest Florida Beaches Intl. Airport (ECP) route, aim to travel before 3 PM. Later departures have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Quad City Intl. Airport (MLI) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Waiting until just before your departure to book a ticket from MLI to ECP generally means paying more. While you may come across some last-minute offers, they aren't always guaranteed. Allow some flexibility in your schedule to boost your chances of scoring a bargain.
Is it cheaper to book a MLI to ECP flight and hotel package?
You'll typically save money by securing a MLI to ECP flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. Once you've selected your ideal flights and accommodations, you can add extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Quad City Intl. Airport (MLI) to Northwest Florida Beaches Intl. Airport (ECP)?
In most instances, you can cancel or modify your MLI to ECP flight. However, additional charges may apply, especially if you made your booking over 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you want more information, head to our Customer Service portal.

Travel information

Travel information

Origin airport
Quad City Intl.
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$242
Distance
810 mi

Book with confidence

Book with confidence

Moline to Panama City Flights

The cheapest times to fly from Moline to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Moline to Panama City are during the month of November. You can find some of the cheapest flights from Moline to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Moline to Panama City

Sunday is one of the best days to book for cheap flights from Moline to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Moline to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Moline to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $100 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Moline to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Moline to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Moline to Panama City Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.