$214 Cheap Flights from State College (SCE) to Knoxville (TYS)

View $214 flight on Wed, Oct 22, 2025Opens in a new window

Popular airlines from State College, PA (SCE-University Park) to McGhee Tyson Airport (TYS)

Cheap Flights from State College to Knoxville (SCE-TYS)

Prices were available within the past 7 days and start at $214 for one-way flights and $234 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Sep 17 - Sat, Sep 20
SCE
State College
TYS
Knoxville
$234 Roundtrip, found 2 hours ago
$234
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Sep 17 from State College to Knoxville, returning Sat, Sep 20, priced at $234 found 2 hours ago
United
Wed, Sep 17 - Sat, Sep 20
SCE
State College
TYS
Knoxville
$239 Roundtrip, found 2 hours ago
$239
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Sep 17 from State College to Knoxville, returning Sat, Sep 20, priced at $239 found 2 hours ago
United
Sat, Sep 13 - Wed, Sep 17
SCE
State College
TYS
Knoxville
$246 Roundtrip, found 5 days ago
$246
Roundtrip
found 5 days ago
Select United flight, departing Sat, Sep 13 from State College to Knoxville, returning Wed, Sep 17, priced at $246 found 5 days ago
United
Wed, Sep 17 - Sat, Sep 20
SCE
State College
TYS
Knoxville
$247 Roundtrip, found 2 hours ago
$247
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Sep 17 from State College to Knoxville, returning Sat, Sep 20, priced at $247 found 2 hours ago
United
Wed, Sep 17 - Sat, Sep 20
SCE
State College
TYS
Knoxville
$248 Roundtrip, found 2 hours ago
$248
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Sep 17 from State College to Knoxville, returning Sat, Sep 20, priced at $248 found 2 hours ago
United
Wed, Sep 10 - Sat, Sep 13
SCE
State College
TYS
Knoxville
$249 Roundtrip, found 5 days ago
$249
Roundtrip
found 5 days ago
Select United flight, departing Wed, Sep 10 from State College to Knoxville, returning Sat, Sep 13, priced at $249 found 5 days ago
United
Sat, Sep 13 - Wed, Sep 17
SCE
State College
TYS
Knoxville
$251 Roundtrip, found 5 days ago
$251
Roundtrip
found 5 days ago
Select United flight, departing Sat, Sep 13 from State College to Knoxville, returning Wed, Sep 17, priced at $251 found 5 days ago
United
Wed, Sep 17 - Sat, Sep 20
SCE
State College
TYS
Knoxville
$253 Roundtrip, found 2 hours ago
$253
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Sep 17 from State College to Knoxville, returning Sat, Sep 20, priced at $253 found 2 hours ago
American Airlines
Wed, Sep 17 - Sat, Sep 20
SCE
State College
TYS
Knoxville
$254 Roundtrip, found 2 hours ago
$254
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Sep 17 from State College to Knoxville, returning Sat, Sep 20, priced at $254 found 2 hours ago
United
Wed, Sep 17 - Sat, Sep 20
SCE
State College
TYS
Knoxville
$258 Roundtrip, found 2 hours ago
$258
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Sep 17 from State College to Knoxville, returning Sat, Sep 20, priced at $258 found 2 hours ago

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McGhee Tyson TYS. Cheapest and Closest option available. Average driving time to city center is 22 minutes. Flights from $308
TYS
McGhee Tyson
CheapestClosest
Average driving time to city center22 min
Flights from $308
Flights from State College (SCE) to Knoxville (TYS)
Origin airport
University Park
Destination airport
McGhee Tyson
Airlines serving
American Airlines, United
Roundtrip price
$233
Distance
481 mi

State College to Knoxville Flights

The cheapest times to fly from State College to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from State College to Knoxville are during the month of September. You can find some of the cheapest flights from State College to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from State College to Knoxville

Sunday is one of the best days to book for cheap flights from State College to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from State College to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from State College to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $214 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap State College to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your State College to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from University Park Airport (SCE) to McGhee Tyson Airport (TYS) cost?
Snag a cheap one-way flight from $214 or cheap return flight from $234 from University Park Airport (SCE) to McGhee Tyson Airport (TYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from University Park Airport (SCE) to McGhee Tyson Airport (TYS)?
The cheapest month to fly from SCE to TYS is September, when there's less demand. Off-peak months are often when better flight deals are available between these airports.
What is the cheapest airline that flies from University Park Airport (SCE) to McGhee Tyson Airport (TYS)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll take you from SCE to TYS. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from University Park Airport (SCE) to McGhee Tyson Airport (TYS)?
Nonstop flights from University Park Airport (SCE) to McGhee Tyson Airport (TYS) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SCE to TYS?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can vary based on a range of factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from University Park Airport (SCE) to McGhee Tyson Airport (TYS)?
To avoid potential delays on the University Park Airport (SCE) to McGhee Tyson Airport (TYS) route, travel before 3 PM. Departures after this hour have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from University Park Airport (SCE) to McGhee Tyson Airport (TYS) last-minute?
Waiting until just before your trip to book a ticket from SCE to TYS often results in higher prices. While you might find some last-minute deals, they aren't always guaranteed. Be flexible with your travel plans for a better chance of scoring a bargain.
Is it cheaper to book a SCE to TYS flight and hotel package?
Opting for a SCE to TYS flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Select from our wide range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from University Park Airport (SCE) to McGhee Tyson Airport (TYS)?
Generally, it's possible to cancel or reschedule your SCE to TYS flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.