$149 Cheap Flights from Louisville (SDF) to Panama City (ECP)

View $149 flight on Wed, Dec 24, 2025Opens in a new window

Popular airlines from Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP)

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Cheap Flights from Louisville to Panama City (SDF-ECP)

Prices were available within the past 7 days and start at $149 for one-way flights and $257 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Feb 17 - Fri, Feb 20
SDF
Louisville
ECP
Panama City
$257 Roundtrip, found 6 days ago
$257
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Feb 17 from Louisville to Panama City, returning Fri, Feb 20, priced at $257 found 6 days ago
Delta
Sat, Jan 17 - Sun, Jan 18
SDF
Louisville
ECP
Panama City
$267 Roundtrip, found 3 days ago
$267
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Jan 17 from Louisville to Panama City, returning Sun, Jan 18, priced at $267 found 3 days ago
American Airlines
Tue, Feb 10 - Tue, Feb 17
SDF
Louisville
ECP
Panama City
$282 Roundtrip, found 3 days ago
$282
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Feb 10 from Louisville to Panama City, returning Tue, Feb 17, priced at $282 found 3 days ago
Delta
Tue, Feb 10 - Tue, Feb 17
SDF
Louisville
ECP
Panama City
$284 Roundtrip, found 3 days ago
$284
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Feb 10 from Louisville to Panama City, returning Tue, Feb 17, priced at $284 found 3 days ago
Southwest Airlines
Tue, Feb 10 - Tue, Feb 17
SDF
Louisville
ECP
Panama City
$287 Roundtrip, found 3 days ago
$287
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Feb 10 from Louisville to Panama City, returning Tue, Feb 17, priced at $287 found 3 days ago
Southwest Airlines
Tue, Feb 10 - Tue, Feb 17
SDF
Louisville
ECP
Panama City
$292 Roundtrip, found 3 days ago
$292
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Feb 10 from Louisville to Panama City, returning Tue, Feb 17, priced at $292 found 3 days ago
Southwest Airlines
Tue, Feb 10 - Tue, Feb 17
SDF
Louisville
ECP
Panama City
$293 Roundtrip, found 3 days ago
$293
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Feb 10 from Louisville to Panama City, returning Tue, Feb 17, priced at $293 found 3 days ago
American Airlines
Mon, Jan 12 - Thu, Jan 15
SDF
Louisville
ECP
Panama City
$297 Roundtrip, found 2 days ago
$297
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Jan 12 from Louisville to Panama City, returning Thu, Jan 15, priced at $297 found 2 days ago
United
Mon, Jan 12 - Thu, Jan 15
SDF
Louisville
ECP
Panama City
$297 Roundtrip, found 2 days ago
$297
Roundtrip
found 2 days ago
Select United flight, departing Mon, Jan 12 from Louisville to Panama City, returning Thu, Jan 15, priced at $297 found 2 days ago
Southwest Airlines
Mon, Jan 12 - Thu, Jan 15
SDF
Louisville
ECP
Panama City
$297 Roundtrip, found 2 days ago
$297
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Mon, Jan 12 from Louisville to Panama City, returning Thu, Jan 15, priced at $297 found 2 days ago

Find the cheapest month to fly from Louisville (SDF) to Panama City (ECP)

August is typically the cheapest month to fly

From $191 - $459 per traveler.

Frequently asked questions

How much does a flight from Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Snag a cheap one-way flight from $149 or cheap return flight from $257 from Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP)?
Planning your trip for February may help you find better deals, as it's the cheapest month for flights between SDF and ECP. You'll often find the lowest fares during off-peak months.
What is the cheapest airline that flies from Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP)?
To find the cheapest airline that'll fly you from SDF to ECP, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP)?
Direct flights from Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SDF to ECP?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP)?
To avoid possible delays on the Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP) route, aim to fly before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Waiting until just before your departure to book a flight from SDF to ECP often results in higher prices. Although you may find some last-minute discounts, they're not always guaranteed. Be flexible with your travel plans for the best chance of snagging a bargain.
Is it cheaper to book a SDF to ECP flight and hotel package?
Compared with arranging flights and hotels separately, booking a SDF to ECP flight and hotel package with Expedia could result in significant savings. Better yet, having it all in one place will take the stress out of planning your trip. Simply pick your flights and select from our wide range of hotels, then personalize your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP)?
It's generally possible to reschedule or cancel your SDF to ECP flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Louisville Intl.
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$256
Distance
541 mi

Book with confidence

Louisville to Panama City Flights

The cheapest times to fly from Louisville to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Louisville to Panama City are during the month of February. You can find some of the cheapest flights from Louisville to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Louisville to Panama City

Sunday is one of the best days to book for cheap flights from Louisville to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Louisville to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Louisville to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $149 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Louisville to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Louisville to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Louisville to Panama City Flights

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*Available to One Key members.