$309 Cheap Flights from Santo Domingo (SDQ) to Panama City (ECP)

View $309 flight on Tue, Jun 9, 2026Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Northwest Florida Beaches Intl. Airport (ECP)

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Cheap Flights from Santo Domingo to Panama City (SDQ-ECP)

Prices were available within the past 7 days and start at $309 for one-way flights and $521 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Jan 23 - Tue, Jan 27
SDQ
Santo Domingo
ECP
Panama City
$521 Roundtrip, found 19 hours ago
$521
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Fri, Jan 23 from Santo Domingo to Panama City, returning Tue, Jan 27, priced at $521 found 19 hours ago
Delta
Sat, Apr 4 - Tue, Apr 14
SDQ
Santo Domingo
ECP
Panama City
$528 Roundtrip, found 5 days ago
$528
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Apr 4 from Santo Domingo to Panama City, returning Tue, Apr 14, priced at $528 found 5 days ago
American Airlines
Fri, Jan 23 - Tue, Jan 27
SDQ
Santo Domingo
ECP
Panama City
$529 Roundtrip, found 19 hours ago
$529
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Fri, Jan 23 from Santo Domingo to Panama City, returning Tue, Jan 27, priced at $529 found 19 hours ago
American Airlines
Sat, Jan 17 - Sat, Jan 24
SDQ
Santo Domingo
ECP
Panama City
$533 Roundtrip, found 21 hours ago
$533
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Santo Domingo to Panama City, returning Sat, Jan 24, priced at $533 found 21 hours ago
American Airlines
Fri, Jan 23 - Tue, Jan 27
SDQ
Santo Domingo
ECP
Panama City
$537 Roundtrip, found 19 hours ago
$537
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Fri, Jan 23 from Santo Domingo to Panama City, returning Tue, Jan 27, priced at $537 found 19 hours ago
American Airlines
Fri, Jan 23 - Tue, Jan 27
SDQ
Santo Domingo
ECP
Panama City
$538 Roundtrip, found 19 hours ago
$538
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Fri, Jan 23 from Santo Domingo to Panama City, returning Tue, Jan 27, priced at $538 found 19 hours ago
Delta
Sat, Apr 4 - Fri, Apr 17
SDQ
Santo Domingo
ECP
Panama City
$540 Roundtrip, found 5 days ago
$540
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Apr 4 from Santo Domingo to Panama City, returning Fri, Apr 17, priced at $540 found 5 days ago
American Airlines
Sat, Jan 17 - Sat, Jan 24
SDQ
Santo Domingo
ECP
Panama City
$540 Roundtrip, found 21 hours ago
$540
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Santo Domingo to Panama City, returning Sat, Jan 24, priced at $540 found 21 hours ago
American Airlines
Mon, Feb 2 - Mon, Feb 9
SDQ
Santo Domingo
ECP
Panama City
$541 Roundtrip, found 6 days ago
$541
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Feb 2 from Santo Domingo to Panama City, returning Mon, Feb 9, priced at $541 found 6 days ago
United
Fri, Jan 23 - Tue, Jan 27
SDQ
Santo Domingo
ECP
Panama City
$1,585 Roundtrip, found 19 hours ago
$1,585
Roundtrip
found 19 hours ago
Select United flight, departing Fri, Jan 23 from Santo Domingo to Panama City, returning Tue, Jan 27, priced at $1,585 found 19 hours ago

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Northwest Florida Beaches Intl. ECP. Cheapest and Closest option available. Average driving time to city center is 35 minutes. Flights from $683
ECP
Northwest Florida Beaches Intl.
CheapestClosest
Average driving time to city center35 min
Flights from $683

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Get a cheap one-way flight from $309 or cheap return flight from $521 from Las Americas Intl. Airport (SDQ) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to Northwest Florida Beaches Intl. Airport (ECP)?
Flying in January is a great way to save, as it's the cheapest month for flights between SDQ and ECP. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to Northwest Florida Beaches Intl. Airport (ECP)?
To find the cheapest airline that'll fly you from SDQ to ECP, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Las Americas Intl. Airport (SDQ) to Northwest Florida Beaches Intl. Airport (ECP)?
Nonstop flights from Las Americas Intl. Airport (SDQ) to Northwest Florida Beaches Intl. Airport (ECP) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SDQ to ECP?
Usually you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Northwest Florida Beaches Intl. Airport (ECP)?
Select a flight from Las Americas Intl. Airport (SDQ) to Northwest Florida Beaches Intl. Airport (ECP) that takes off before 3 PM to reduce the risk of cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Booking your ticket from SDQ to ECP just before your journey is generally more expensive. But if there's some wiggle room with your travel dates and times, you could grab a cheap last-minute fare.
Is it cheaper to book a SDQ to ECP flight and hotel package?
Opting for a SDQ to ECP flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Choose from our impressive range of accommodations and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Northwest Florida Beaches Intl. Airport (ECP)?
In most instances, you're able to cancel or reschedule your SDQ to ECP flight. However, there may be additional charges, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you need more details, go to our Customer Service portal.

Travel information

Origin airport
Las Americas Intl.
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$520
Distance
1304 mi

Book with confidence

Santo Domingo to Panama City Flights

The cheapest times to fly from Santo Domingo to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Panama City are during the month of January. You can find some of the cheapest flights from Santo Domingo to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Panama City

Sunday is one of the best days to book for cheap flights from Santo Domingo to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $309 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santo Domingo to Panama City Flights

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