$474 Cheap Flights from San Francisco (SFO) to La Crosse (LSE)

View $474 flight on Tue, Dec 30, 2025Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to La Crosse, WI (LSE-La Crosse Municipal)

Cheap Flights from San Francisco to La Crosse (SFO-LSE)

Prices were available within the past 7 days and start at $474 for one-way flights and $454 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Jan 14 - Sat, Jan 17
SFO
San Francisco
LSE
La Crosse
$454 Roundtrip, found 6 days ago
$454
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jan 14 from San Francisco to La Crosse, returning Sat, Jan 17, priced at $454 found 6 days ago
American Airlines
Wed, Dec 10 - Sat, Dec 13
SFO
San Francisco
LSE
La Crosse
$460 Roundtrip, found 6 days ago
$460
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Dec 10 from San Francisco to La Crosse, returning Sat, Dec 13, priced at $460 found 6 days ago
American Airlines
Wed, Nov 26 - Wed, Dec 3
SFO
San Francisco
LSE
La Crosse
$490 Roundtrip, found 2 days ago
$490
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Nov 26 from San Francisco to La Crosse, returning Wed, Dec 3, priced at $490 found 2 days ago
American Airlines
Wed, Nov 5 - Sat, Nov 8
SFO
San Francisco
LSE
La Crosse
$506 Roundtrip, found 3 days ago
$506
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Nov 5 from San Francisco to La Crosse, returning Sat, Nov 8, priced at $506 found 3 days ago
American Airlines
Wed, Nov 19 - Sat, Nov 22
SFO
San Francisco
LSE
La Crosse
$512 Roundtrip, found 6 days ago
$512
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Nov 19 from San Francisco to La Crosse, returning Sat, Nov 22, priced at $512 found 6 days ago
American Airlines
Wed, Nov 5 - Sat, Nov 8
SFO
San Francisco
LSE
La Crosse
$523 Roundtrip, found 3 days ago
$523
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Nov 5 from San Francisco to La Crosse, returning Sat, Nov 8, priced at $523 found 3 days ago
American Airlines
Wed, Nov 5 - Sat, Nov 8
SFO
San Francisco
LSE
La Crosse
$526 Roundtrip, found 8 hours ago
$526
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Nov 5 from San Francisco to La Crosse, returning Sat, Nov 8, priced at $526 found 8 hours ago
American Airlines
Wed, Nov 5 - Sat, Nov 8
SFO
San Francisco
LSE
La Crosse
$540 Roundtrip, found 5 days ago
$540
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Nov 5 from San Francisco to La Crosse, returning Sat, Nov 8, priced at $540 found 5 days ago
American Airlines
Wed, Nov 5 - Sat, Nov 8
SFO
San Francisco
LSE
La Crosse
$543 Roundtrip, found 19 hours ago
$543
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Nov 5 from San Francisco to La Crosse, returning Sat, Nov 8, priced at $543 found 19 hours ago
American Airlines
Wed, Jan 14 - Sat, Jan 17
SFO
San Francisco
LSE
La Crosse
$544 Roundtrip, found 6 days ago
$544
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jan 14 from San Francisco to La Crosse, returning Sat, Jan 17, priced at $544 found 6 days ago

Frequently asked questions

How much does a flight from San Francisco Intl. Airport (SFO) to La Crosse Municipal Airport (LSE) cost?
Snag a cheap one-way flight from $474 or cheap return flight from $454 from San Francisco Intl. Airport (SFO) to La Crosse Municipal Airport (LSE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from San Francisco Intl. Airport (SFO) to La Crosse Municipal Airport (LSE)?
The cheapest month to fly from SFO to LSE is January, when demand is low. Off-peak months are often when airlines offer better prices between these airports.
What is the cheapest airline that flies from San Francisco Intl. Airport (SFO) to La Crosse Municipal Airport (LSE)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest SFO to LSE flight.
How many flights per day from San Francisco Intl. Airport (SFO) to La Crosse Municipal Airport (LSE)?
You'll need to hop on a flight with a layover when traveling from San Francisco Intl. Airport (SFO) to La Crosse Municipal Airport (LSE). There are no daily direct flights on this route. However, simply filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from SFO to LSE?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change based on a number of factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Francisco Intl. Airport (SFO) to La Crosse Municipal Airport (LSE)?
To avoid possible delays on the San Francisco Intl. Airport (SFO) to La Crosse Municipal Airport (LSE) route, aim to travel before 3 PM. Flights after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Francisco Intl. Airport (SFO) to La Crosse Municipal Airport (LSE) last-minute?
Holding off until just before your trip to book a flight from SFO to LSE often results in higher prices. Although you may find some last-minute deals, they aren't always guaranteed. Keep your travel plans flexible for a better chance of scoring a bargain.
Is it cheaper to book a SFO to LSE flight and hotel package?
Securing a SFO to LSE flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Choose from our extensive range of stays and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from San Francisco Intl. Airport (SFO) to La Crosse Municipal Airport (LSE)?
Generally, it's possible to cancel or reschedule your SFO to LSE flight. However, for bookings made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
San Francisco Intl.
Destination airport
La Crosse Municipal
Roundtrip price
$454
Distance
1674 mi

Book with confidence

San Francisco to La Crosse Flights

The cheapest times to fly from San Francisco to La Crosse

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Francisco to La Crosse are during the month of January. You can find some of the cheapest flights from San Francisco to La Crosse with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Francisco to La Crosse

Sunday is one of the best days to book for cheap flights from San Francisco to La Crosse: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Francisco to La Crosse

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Francisco to La Crosse in 2025. You can also book with separate airlines for your outbound and return journeys, from $474 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Francisco to La Crosse flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Francisco to La Crosse airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

San Francisco to La Crosse Flights

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*Available to One Key members.