$289 Cheap Flights from Knoxville (TYS) to Casper (CPR)

View $289 flight on Mon, Nov 10, 2025Opens in a new window

Popular airlines from McGhee Tyson Airport (TYS) to Casper, WY (CPR-Natrona County Intl.)

Cheap Flights from Knoxville to Casper (TYS-CPR)

Prices were available within the past 7 days and start at $289 for one-way flights and $336 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Sat, Oct 18 - Sun, Oct 19
TYS
Knoxville
CPR
Casper
$336 Roundtrip, found 6 days ago
$336
Roundtrip
found 6 days ago
Select United flight, departing Sat, Oct 18 from Knoxville to Casper, returning Sun, Oct 19, priced at $336 found 6 days ago
United
Wed, Jan 7 - Mon, Jan 12
TYS
Knoxville
CPR
Casper
$338 Roundtrip, found 4 days ago
$338
Roundtrip
found 4 days ago
Select United flight, departing Wed, Jan 7 from Knoxville to Casper, returning Mon, Jan 12, priced at $338 found 4 days ago
United
Sat, Jan 10 - Mon, Jan 12
TYS
Knoxville
CPR
Casper
$344 Roundtrip, found 4 days ago
$344
Roundtrip
found 4 days ago
Select United flight, departing Sat, Jan 10 from Knoxville to Casper, returning Mon, Jan 12, priced at $344 found 4 days ago
United
Sat, Jan 10 - Sat, Jan 17
TYS
Knoxville
CPR
Casper
$349 Roundtrip, found 4 days ago
$349
Roundtrip
found 4 days ago
Select United flight, departing Sat, Jan 10 from Knoxville to Casper, returning Sat, Jan 17, priced at $349 found 4 days ago
United
Sat, Oct 18 - Sat, Oct 25
TYS
Knoxville
CPR
Casper
$363 Roundtrip, found 5 days ago
$363
Roundtrip
found 5 days ago
Select United flight, departing Sat, Oct 18 from Knoxville to Casper, returning Sat, Oct 25, priced at $363 found 5 days ago
United
Fri, Oct 10 - Mon, Oct 20
TYS
Knoxville
CPR
Casper
$369 Roundtrip, found 3 days ago
$369
Roundtrip
found 3 days ago
Select United flight, departing Fri, Oct 10 from Knoxville to Casper, returning Mon, Oct 20, priced at $369 found 3 days ago
United
Tue, Jan 6 - Sat, Jan 17
TYS
Knoxville
CPR
Casper
$374 Roundtrip, found 4 days ago
$374
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jan 6 from Knoxville to Casper, returning Sat, Jan 17, priced at $374 found 4 days ago
United
Sat, Oct 18 - Sun, Oct 19
TYS
Knoxville
CPR
Casper
$382 Roundtrip, found 6 days ago
$382
Roundtrip
found 6 days ago
Select United flight, departing Sat, Oct 18 from Knoxville to Casper, returning Sun, Oct 19, priced at $382 found 6 days ago
United
Fri, Oct 10 - Fri, Oct 17
TYS
Knoxville
CPR
Casper
$385 Roundtrip, found 3 days ago
$385
Roundtrip
found 3 days ago
Select United flight, departing Fri, Oct 10 from Knoxville to Casper, returning Fri, Oct 17, priced at $385 found 3 days ago
United
Fri, Oct 10 - Fri, Oct 17
TYS
Knoxville
CPR
Casper
$387 Roundtrip, found 3 days ago
$387
Roundtrip
found 3 days ago
Select United flight, departing Fri, Oct 10 from Knoxville to Casper, returning Fri, Oct 17, priced at $387 found 3 days ago

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Natrona County Intl. Airport (CPR) cost?
Secure a cheap one-way flight from $289 or cheap return flight from $336 from McGhee Tyson Airport (TYS) to Natrona County Intl. Airport (CPR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Natrona County Intl. Airport (CPR)?
The cheapest month to fly from TYS to CPR is October, when demand is low. Off-peak months are often when airlines offer better prices between these airports.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to Natrona County Intl. Airport (CPR)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest TYS to CPR flight.
How many flights per day from McGhee Tyson Airport (TYS) to Natrona County Intl. Airport (CPR)?
Direct flights from McGhee Tyson Airport (TYS) to Natrona County Intl. Airport (CPR) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel details and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TYS to CPR?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can change depending on a number of factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Natrona County Intl. Airport (CPR)?
To touch down at Natrona County Intl. Airport (CPR) on schedule, opt for a flight that leaves McGhee Tyson Airport (TYS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Natrona County Intl. Airport (CPR) last-minute?
Booking your ticket from TYS to CPR just before your getaway is generally more expensive. But if there's some wiggle room with your departure times and dates, you could grab a cheap last-minute fare.
Is it cheaper to book a TYS to CPR flight and hotel package?
You can save money by booking a TYS to CPR flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. Once you've chosen your preferred flights and accommodations, you can add extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Natrona County Intl. Airport (CPR)?
If you reserved your TYS to CPR flight in the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more information.

Travel information

Travel information

Origin airport
McGhee Tyson
Destination airport
Natrona County Intl.
Airlines serving
United
Roundtrip price
$336
Distance
1291 mi

Book with confidence

Book with confidence

Knoxville to Casper Flights

The cheapest times to fly from Knoxville to Casper

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Casper are during the month of October. You can find some of the cheapest flights from Knoxville to Casper with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Casper

Sunday is one of the best days to book for cheap flights from Knoxville to Casper: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Casper

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Casper in 2025. You can also book with separate airlines for your outbound and return journeys, from $289 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Casper flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Casper airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Casper Flights

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*Available to One Key members.