$167 Cheap American Airlines flights Boston (BOS) to St. Louis (STL)

You'll discover budget-friendly return American Airlines flights from $247 from BOS to STL by organizing your results from "Price (lowest to highest)" on Expedia. Or search for deals from $167 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months ahead of your travel date to score cheap fares on American Airlines flights from Logan Intl. Airport (BOS) to Lambert-St. Louis Intl. Airport (STL). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The first flight from BOS to STL with American Airlines departs at 6:30AM UTC-5. You'll land at 8:54AM UTC-6. The last American Airlines flight of the day takes off at 10:38AM UTC-5 and arrives at 1:00PM UTC-6. With approximately 20% fewer cancellations for morning departures, starting your travel day early is typically the wisest option.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.