$170 Cheap American Airlines flights Monroe (MLU) to Detroit (DTW)

Use the "Price (lowest to highest)" filter on Expedia to look for cheap American Airlines return flights from $268 from MLU to DTW. Affordable one-way tickets from $170 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months ahead of your travel date to get cheaper fares on American Airlines flights from Monroe Regional Airport (MLU) to Detroit Metropolitan Wayne County Airport (DTW). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Time it well, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from MLU to DTW with American Airlines, filter your results by "Morning" and "Early Morning." Booking an early flight generally means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.