$609 Cheap American Airlines flights Myrtle Beach (MYR) to Florence (FLR)

Use the "Price (lowest to highest)" filter on Expedia to find cheap American Airlines return flights from $1,453 from MYR to FLR. Affordable one-way options from $609 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To find affordable flights from MYR to FLR with American Airlines, begin your search about one month before your planned departure. You can save 17% when you book your international tickets 18 to 29 days ahead instead of booking four to five months in advance. Another useful tip? Booking on Sunday can lead to average savings of 17% compared to Friday (the most expensive day).**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Morning" and "Early Morning" to browse the earliest flights from MYR to FLR. Jetting off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.