$126 Cheap Delta flights Des Moines (DSM) to Myrtle Beach (MYR)

Use the "Price (lowest to highest)" filter on Expedia to find cheap Delta Air Lines return flights from $248 from DSM to MYR. Affordable one-way options from $126 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

For cheap Delta Air Lines fares from Des Moines Intl. Airport (DSM) to Myrtle Beach Intl. Airport (MYR), start searching one to three months before your intended departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also impact the price you pay. Sunday is usually the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your trip on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from DSM to MYR with Delta Air Lines, sort your results by "Early Morning" and "Morning." Booking an early flight usually means you'll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Delta Air Lines makes traveling from DSM to MYR more enjoyable with an excellent in-flight experience and a rewarding loyalty program. You could even start earning points with Delta SkyMiles. Don't forget to join Expedia's free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future trips.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.