$125 Cheap Delta flights Moline (MLI) to Knoxville (TYS)

Finding cheap one-way Delta Air Lines flights from MLI to TYS from $125 on Expedia couldn't be easier — just filter by "Price (lowest to highest)." Alternatively, check out our affordable round-trip fares from $278 for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

For cheap Delta Air Lines fares from Quad City Intl. Airport (MLI) to McGhee Tyson Airport (TYS), start searching one to three months before your intended departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect how much you pay. Sunday is usually the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your flight on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Early Morning" and "Morning" to see the earliest departures from MLI to TYS. Taking off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Delta Air Lines makes flying from MLI to TYS more comfortable with a rewarding loyalty program and an excellent in-flight experience. You may even earn points with Delta SkyMiles. Be sure to sign up to our free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future trips.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.