$173 Cheap JetBlue Airways flights Buffalo (BUF) to San Diego (SAN)

Finding cheap one-way JetBlue Airways flights from BUF to SAN from $173 on Expedia is simple — just filter by "Price (lowest to highest)." Alternatively, check out our affordable return fares from $319 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for affordable JetBlue Airways flights from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN) one to three months prior to your departure day. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and itinerary, the best day to book a domestic flight is usually Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from BUF to SAN with JetBlue Airways, filter your search by "Early Morning" and "Morning." Choosing an early flight generally means you'll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.