$1,541 Cheap KLM flights Madrid (MAD) to San Diego (SAN)

Finding cheap one-way KLM flights from MAD to SAN from $1,541 on Expedia couldn't be simpler — just filter by "Price (lowest to highest)." Alternatively, check out our affordable return fares from $871 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To grab affordable flights from MAD to SAN with KLM, start searching about one month before your planned departure. You can save 17% when you lock in your international tickets 18 to 29 days ahead instead of booking four to five months in advance. Another helpful tip? Booking on Sunday offers average savings of 17% compared to Friday (the most expensive day).**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Early Morning" and "Morning" to browse the earliest flights from MAD to SAN. Heading off early means you're 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

A 4-star airline rating and the ability to rack up points through KLM Flying Blue are the start of the reasons to depart from MAD to SAN with KLM. Plus, by joining Expedia's free One Key™ program, you can earn OneKeyCash™* alongside KLM's loyalty program earnings. It's yours to spend on your next adventure.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.