Cheap Spirit Airlines flights Myrtle Beach (MYR) to San Diego (SAN)

You can discover budget-friendly return Spirit Airlines flights from $289 from MYR to SAN by organizing your results from "Price (lowest to highest)" on Expedia. Or search for deals for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for affordable Spirit Airlines flights from Myrtle Beach Intl. Airport (MYR) to San Diego Intl. Airport (SAN) one to three months ahead of your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and journey, the ideal day to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Early Morning" and "Morning" to browse the earliest departures from MYR to SAN. Setting off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Fly from MYR to SAN with Spirit Airlines and you'll enjoy a host of benefits starting with a rewarding loyalty program. When you book through Expedia as a Free Spirit and One Key™ member, you may also earn OneKeyCash™* to redeem on select future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.