$100 Cheap United flights New Orleans (MSY) to Knoxville (TYS)

You'll discover cheap round-trip United Airlines flights from $244 from MSY to TYS by sorting your results from "Price (lowest to highest)" on Expedia. Or look for options from $100 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for cheap United Airlines flights from Louis Armstrong New Orleans Intl. Airport (MSY) to McGhee Tyson Airport (TYS) one to three months before your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and itinerary, the ideal day to book a domestic flight is generally Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Find United Airlines's earliest flights from MSY to TYS by selecting our "Morning" and "Early Morning" filters. Not only will you arrive sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

A rewarding loyalty program and the opportunity to collect points through United Mileage Plus are the start of the reasons to fly from MSY to TYS with United Airlines. Plus, when you join Expedia's free One Key™ program, you can receive OneKeyCash™* on top of any airline loyalty program earnings. It's yours to use wherever your next trip takes you.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.