$179 Cheap United flights Manchester (MHT) to Knoxville (TYS)

You'll find affordable return United Airlines flights from $353 from MHT to TYS by filtering your results from "Price (lowest to highest)" on Expedia. Or search for deals from $179 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for cheap United Airlines flights from Manchester-Boston Regional Airport (MHT) to McGhee Tyson Airport (TYS) one to three months ahead of your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare type and journey, the best day of the week to book a domestic flight is usually Sunday and the most expensive day tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Early Morning" and "Morning" to see the earliest flights from MHT to TYS. Leaving early means you're 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Depart from MHT to TYS with United Airlines and you'll enjoy a range of benefits starting with a rewarding loyalty program. When booking through Expedia as a United Mileage Plus and One Key™ member, you can also earn OneKeyCash™* to use on select future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.