$540 Cheap Flights from Florence (FLR) to San Diego (SAN)

View $540 flight on Thu, Jun 4, 2026Opens in a new window

Popular airlines from Florence Airport, Peretola (FLR) to San Diego Intl. Airport (SAN)

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Cheap Flights from Florence to San Diego (FLR-SAN)

Prices were available within the past 7 days and start at $540 for one-way flights and $890 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Dolomiti
Fri, May 8 - Sat, May 9
FLR
Florence
SAN
San Diego
$890 Roundtrip, found 1 day ago
$890
Roundtrip
found 1 day ago
Select Air Dolomiti flight, departing Fri, May 8 from Florence to San Diego, returning Sat, May 9, priced at $890 found 1 day ago
Air Dolomiti
Fri, Oct 16 - Sat, Oct 17
FLR
Florence
SAN
San Diego
$900 Roundtrip, found 2 days ago
$900
Roundtrip
found 2 days ago
Select Air Dolomiti flight, departing Fri, Oct 16 from Florence to San Diego, returning Sat, Oct 17, priced at $900 found 2 days ago
Air Dolomiti
Fri, Oct 16 - Sat, Oct 17
FLR
Florence
SAN
San Diego
$910 Roundtrip, found 2 days ago
$910
Roundtrip
found 2 days ago
Select Air Dolomiti flight, departing Fri, Oct 16 from Florence to San Diego, returning Sat, Oct 17, priced at $910 found 2 days ago
Air Dolomiti
Fri, May 8 - Sat, May 9
FLR
Florence
SAN
San Diego
$960 Roundtrip, found 1 day ago
$960
Roundtrip
found 1 day ago
Select Air Dolomiti flight, departing Fri, May 8 from Florence to San Diego, returning Sat, May 9, priced at $960 found 1 day ago
Air Canada
Wed, Nov 11 - Tue, Nov 17
FLR
Florence
SAN
San Diego
$994 Roundtrip, found 2 days ago
$994
Roundtrip
found 2 days ago
Select Air Canada flight, departing Wed, Nov 11 from Florence to San Diego, returning Tue, Nov 17, priced at $994 found 2 days ago
British Airways
Thu, Sep 17 - Fri, Oct 16
FLR
Florence
SAN
San Diego
$995 Roundtrip, found 2 days ago
$995
Roundtrip
found 2 days ago
Select British Airways flight, departing Thu, Sep 17 from Florence to San Diego, returning Fri, Oct 16, priced at $995 found 2 days ago
Lufthansa
Tue, Apr 28 - Wed, May 6
FLR
Florence
SAN
San Diego
$995 Roundtrip, found 1 day ago
$995
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Tue, Apr 28 from Florence to San Diego, returning Wed, May 6, priced at $995 found 1 day ago
Swiss International Air Lines
Tue, Apr 28 - Wed, May 6
FLR
Florence
SAN
San Diego
$1,002 Roundtrip, found 1 day ago
$1,002
Roundtrip
found 1 day ago
Select Swiss International Air Lines flight, departing Tue, Apr 28 from Florence to San Diego, returning Wed, May 6, priced at $1,002 found 1 day ago
Austrian Airlines
Tue, Apr 28 - Wed, May 6
FLR
Florence
SAN
San Diego
$1,011 Roundtrip, found 1 day ago
$1,011
Roundtrip
found 1 day ago
Select Austrian Airlines flight, departing Tue, Apr 28 from Florence to San Diego, returning Wed, May 6, priced at $1,011 found 1 day ago
Iberia
Wed, Nov 11 - Tue, Nov 17
FLR
Florence
SAN
San Diego
$1,017 Roundtrip, found 2 days ago
$1,017
Roundtrip
found 2 days ago
Select Iberia flight, departing Wed, Nov 11 from Florence to San Diego, returning Tue, Nov 17, priced at $1,017 found 2 days ago

Find the cheapest month to fly from Florence (FLR) to San Diego (SAN)

September is typically the cheapest month to fly

From $738 - $1,440 per traveler.

Frequently asked questions

How much does a flight from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.) cost?
You can find cheap one-way flights from $540 and cheap return flights from $890 Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.) with Expedia. One-way flights usually range from $717 to $4100, and return flights typically cost between $950 and $4415. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.)?
The cheapest month to fly from FLR to SAN is May when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.)?
Enter FLR to SAN and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.)?
Lufthansa is one of the cheapest airlines offering connecting flights from Peretola (FLR) to San Diego Intl. (SAN), with round-trip tickets starting from around $897 with a layover in Frankfurt Intl. (FRA). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.)?
To find a cheap flight from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.)?
The earliest flight from Florence (Peretola) to San Diego, CA (San Diego International) usually departs at around 6:05 AM, operated by Helvetic Airways, Swiss International Air Lines, and Air Canada. This seasonal service is available in October, giving you an early start to enjoy San Diego. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.)?
The most popular departure times for flights from Florence (FLR) to San Diego (SAN) are in the early morning, from 6am to 9am. About 66% of passengers prefer this time window. Many major carriers, including Lufthansa and United Airlines, offer flights during this window. This timing is great for travelers looking to make the most of their day in San Diego.
How long does it take to fly from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.)?
A flight from FLR to SAN with a layover takes around 16 hours 50 minutes, with the route covering approximately 6,230 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.)?
You can fly business class between FLR and SAN. Airlines that offer business class service on this route include:

  • Air Dolomiti
  • Swiss International Air Lines
  • Lufthansa
  • Austrian Airlines
  • ITA Airways
  • British Airways
  • Helvetic Airways
  • KLM
  • SAS
  • Iberia

How do I earn miles on a Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.) flight with Expedia?
It's easy to earn miles on a Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for San Diego from Peretola (FLR)?
If you're planning to travel to San Diego from Peretola (FLR), you can fly into San Diego Intl. (SAN) Some flights may connect through major hubs like Frankfurt Intl. (FRA), Franz Josef Strauss Intl. (MUC), Roissy-Charles de Gaulle (CDG) before reaching San Diego. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.) at the last minute?
Typically, booking a last minute flight from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.) flight and hotel package?
Securing a Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.) San Diego Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.)?
If you booked your Florence (FLR-Peretola) to San Diego, CA (SAN-San Diego Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Peretola
Destination airport
San Diego Intl.
Airlines serving
Air Canada, Austrian Airlines, British Airways, Brussels Airlines, ITA Airways, Iberia, Lufthansa, Scandinavian Airlines, Swiss International Air Lines, TAP Portugal
Roundtrip price
$890
Distance
6229 mi

Book with confidence

Florence to San Diego Flights

The cheapest times to fly from Florence to San Diego

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Florence to San Diego are during the month of May. You can find some of the cheapest flights from Florence to San Diego with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Florence to San Diego

Sunday is one of the best days to book for cheap flights from Florence to San Diego: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Florence to San Diego

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Florence to San Diego in 2026. You can also book with separate airlines for your outbound and return journeys, from $540 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Florence to San Diego flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Florence to San Diego airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Florence to San Diego Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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