$129 Cheap Flights from Buffalo (BUF) to Greenville (GSP)
Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Greenville-Spartanburg Intl. Airport (GSP)
American AirlinesAmerican Airlines
DeltaDelta
Southwest AirlinesSouthwest Airlines
UnitedUnited
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Cheap Flights from Buffalo to Greenville (BUF-GSP)
Alternative airports near Greenville
Prices were available within the past 7 days. Prices and availability are subject to change.
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Buffalo (BUF) to Greenville (GSP) at a glance
Explore a range of options for flights from Buffalo (BUF) to Greenville (GSP) on this domestic short-haul route. Whether you're looking for full-service airlines or budget-friendly carriers, you can compare choices to find the best itinerary that aligns with your budget and travel plans. Discover key details about Buffalo to Greenville flights and prepare to experience the charming sights and neighborhoods that Greenville has to offer.
- Fastest flight duration: around 3 hours in-flight, plus roughly 1 hour layover with one stop
- Route distance: roughly 600 miles (970 km)
- Flights per week: around 10 departures on average
- Typical fares (one-way): economy tickets often range from $110–$350, depending on seasonality and how far ahead you book
Flights from Buffalo Niagara International Airport (BUF) to Greenville-Spartanburg International Airport (GSP)
Based on recent traveler bookings, the most popular airlines flying from Buffalo to Greenville often feature one-stop services with convenient layovers at Charlotte-Douglas International Airport (CLT, approximately 1 hour), Baltimore Washington International Thurgood Marshall Airport (BWI, around 1 hour), and LaGuardia Airport (LGA, about 1 hour and 15 minutes). These options allow you to tailor your journey by balancing price, total travel time, and cabin class to discover the best itinerary for your needs.
- American Airlines: This established full-service airline provides one-stop flights, with one-way ticket prices generally falling between $110 and $320. It operates around 54% of the flights on this route, featuring an in-flight duration of 3 hours and a total travel time of approximately 4 hours and 15 minutes, including layover time.
- Southwest Airlines: Known for its budget-friendly options, this low-cost carrier offers one-stop service, with one-way fares typically ranging from $110 to $375. Southwest handles about 19% of the departures on this route, with an in-flight duration of 3 hours and an overall journey time of roughly 4 hours and 15 minutes, including a layover.
- Delta: A prominent full-service airline, Delta provides one-stop flights with one-way fares generally priced between $110 and $380. It accounts for approximately 19% of the departures along this route and has an in-flight time of 3 hours, leading to a total travel duration of about 4 hours and 15 minutes, including layover.
- United: As a full-service airline, United offers one-stop flights, with one-way fares typically ranging from $120 to $455. Covering about 9% of the departures on this route, passengers can expect an in-flight time of 3 hours, culminating in a total journey time of roughly 4 hours and 15 minutes, including layover.
Best time to fly from Buffalo (BUF) to Greenville (GSP)
The most popular months for travelers flying from Buffalo to Greenville are March, April, and October, when peak temperatures in Greenville reach up to 61.9°F in October. If you prefer quieter travel, consider September, the least busy time to visit with temperatures around 72.3°F and typically the lowest average one-way fare (around $183). Flight availability peaks in October, with approximately 12 flights per week, making it easier to find convenient departure times. February has the fewest flights, with approximately 8 flights per week.
- Cheapest time to fly: September usually offers good deals with average one-way fare around $183, roughly 11% cheaper than the yearly average.
- More budget-friendly months to fly: May, January, and July typically offer average one-way fares of around $194.
- Most flight options: October has the highest number of flights from Buffalo to Greenville, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.
| Month | Temperature | Demand | Weekly Flights | Average one-way Fare |
| January | 41.4°F (5.2°C) | Low | 9 | $196 |
| February | 45.3°F (7.4°C) | Average | 8 | $224 |
| March | 51.8°F (11.0°C) | High | 9 | $222 |
| April | 59.9°F (15.5°C) | High | 11 | $209 |
| May | 68.4°F (20.2°C) | Average | 11 | $189 |
| June | 76.1°F (24.5°C) | Average | 9 | $202 |
| July | 79.5°F (26.4°C) | Average | 11 | $198 |
| August | 77.5°F (25.3°C) | Average | 10 | $202 |
| September | 72.3°F (22.4°C) | Low | 9 | $183 |
| October | 61.9°F (16.6°C) | High | 12 | $199 |
| November | 51.1°F (10.6°C) | Average | 10 | $231 |
| December | 45.3°F (7.4°C) | Low | 9 | $229 |
*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.
Alternative route from Buffalo (BUF) to Greenville (GSP)
- Rochester to Greenville (ROC-GSP): Greater Rochester International Airport (ROC) is located approximately 56 miles from Buffalo Niagara International Airport (BUF). On this route, one-way economy prices generally vary from $110 to $380, influenced by the season and how far in advance you book. This route is often served by one-stop flights, with common layover points including Charlotte-Douglas International Airport (CLT) and LaGuardia Airport (LGA). Major airlines operating this route are American Airlines and Delta, and first-class service is also offered.
How to find the best prices for flights from Buffalo (BUF) to Greenville (GSP)
Getting some of the best deals on flights from Buffalo to Greenville is all about timing and flexibility. Here are some key tips to help you save:
- Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, which coincides with when most travelers make their reservations. Morning departures between 5 am and 12 pm typically offer lower prices and are also the most popular. Additionally, flying on Tuesday generally provides cheaper rates, although Thursday remains the most favored travel day.
- Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
- Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Greenville hotel and flight deals.
- Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
- Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
- Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.
*Members only. Savings vary and are not available on all bundles. Select hotels.
Arriving at Greenville-Spartanburg International Airport from Buffalo Niagara International Airport
Greenville welcomes travelers from Buffalo with a range of transport options based on price, convenience, and proximity. Greenville city center is approximately a 20-minute drive (covering about 16 miles) from Greenville-Spartanburg International Airport, depending on traffic. Here's how to reach Greenville efficiently:
- Hotel transfer: Transfers offer a convenient way to reach your hotel in Greenville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
- Car rental: Renting a car from Greenville-Spartanburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Greenville-Spartanburg International Airport on Expedia.
- Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
Buffalo to Greenville Flights
The cheapest times to fly from Buffalo to Greenville
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Greenville are during the month of November. You can find some of the cheapest flights from Buffalo to Greenville with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Buffalo to Greenville
Sunday is one of the best days to book for cheap flights from Buffalo to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Buffalo to Greenville
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Greenville in 2026. You can also book with separate airlines for your outbound and return journeys, from $129 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently Asked Questions
How much does a flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) cost?
You can find cheap one-way flights from $129 and cheap return flights $257 Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) with Expedia. One-way flights typically cost between $181 and $686, and return flights often range between $342 and $1127. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) ticket fares go up or down.
*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
September is the cheapest month to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), with average return fares around $326. This price is about 17% lower than the average fare throughout the year, as travel demand typically decreases after the summer. Other cheap months to fly from Buffalo to Greenville include February and July.
*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Enter BUF to GSP and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting flights from Buffalo Niagara Intl. (BUF) to Greenville-Spartanburg Intl. (GSP), with round-trip tickets starting from around $191 with a layover in Baltimore Washington Intl. Thurgood Marshall (BWI). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
To find a cheap flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The ideal months to fly from Buffalo, NY (BUF) to Greenville, SC (GSP) are September and February. With average return flight prices around $326, these months strike a balance between affordability and travel experience. September offers pleasant weather, while February can be a quieter time to visit.
*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The earliest flight from Buffalo, NY (BUF) to Greenville, SC (GSP) typically departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in December, allowing you to start your day early and enjoy more time in South Carolina. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The most popular departure times for flights from Buffalo, NY (BUF) to Greenville, SC (GSP) are in the early morning, from 6am to 9am. About 31% of passengers prefer this time window. Many major carriers, including American Airlines, Delta and United Airlines, offer flights during this window, making it a convenient option for early risers.
How long does it take to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Flights from BUF to GSP with one stop typically take around 4 hours 50 minutes, covering approximately 586 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
First class is available on flights from BUF to GSP. First class cabins are available on:
- Delta Air Lines
- American Airlines
- United Airlines
How do I earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight with Expedia?
It's easy to earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.
*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Greenville from Buffalo Niagara Intl. (BUF)?
When traveling from Buffalo Niagara Intl. (BUF) to Greenville, you can fly into Greenville-Spartanburg Intl. (GSP) and Pitt-Greenville (PGV). Some flights may connect through major hubs like Liberty Intl. (EWR), Washington Dulles Intl. (IAD), O'Hare Intl. (ORD) before reaching Greenville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) at the last minute?
Typically, booking a last minute flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package?
Securing a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
If you booked your Buffalo, NY (BUF-Buffalo Niagara Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.
Travel information
Origin airport | Buffalo Niagara Intl. Airport |
|---|---|
Destination airport | Greenville-Spartanburg Intl. Airport |
Distance | 586 miles away |
Airlines serving | American Airlines, Delta, Southwest Airlines, United |
Popular airline | American Airlines |
Roundtrip price | $257 |