$134 Cheap Flights from Cleveland (CLE) to Panama City (ECP)
Popular airlines from Cleveland Hopkins International Airport (CLE) to Northwest Florida Beaches Intl. Airport (ECP)
DeltaDelta
American AirlinesAmerican Airlines
UnitedUnited
Southwest AirlinesSouthwest Airlines
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Cheap Flights from Cleveland to Panama City (CLE-ECP)
Alternative airports near Panama City
Prices were available within the past 7 days. Prices and availability are subject to change.
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Cleveland (CLE) to Panama City (ECP) at a glance
Travel from Cleveland (CLE) to Panama City (ECP) with a range of airline options available on this domestic short-haul route. You can compare prices and schedules for various carriers, whether you prefer full-service airlines or low-cost choices. This way, you'll find the ideal itinerary that suits your budget and travel plans as you discover Panama City's renowned attractions and neighborhoods. Here, we provide essential details for flights from Hopkins International Airport (CLE) to Northwest Florida Beaches International Airport (ECP).
- Fastest flight duration: around 3h 15m in-flight, plus roughly 1h 15m layover with one stop
- Route distance: roughly 800 miles (1,290 km)
- Flights per week: around 11 departures on average
- Typical fares (one-way): economy tickets often range from $120–$440, depending on seasonality and how far ahead you book
Flights from Hopkins International Airport (CLE) to Northwest Florida Beaches International Airport (ECP)
According to recent traveler bookings, the top airlines flying from Cleveland to Panama City are often favored for their one-stop service, with common layovers at Hartsfield-Jackson Atlanta International Airport (ATL, approximately 1 hour 30 minutes), Charlotte-Douglas International Airport (CLT, around 1 hour 30 minutes), and Nashville International Airport (BNA, about 50 minutes). These options provide flexibility in selecting the best itinerary based on price, total travel time, and cabin class.
- Delta: As a full-service airline, Delta provides a convenient one-stop option with one-way fares typically between $120 and $445. This carrier represents around 49% of departures on this route, featuring an in-flight duration of 3 hours and 15 minutes, and a total travel time of approximately 4 hours and 45 minutes, including the layover.
- American Airlines: Known for its comprehensive service, American Airlines offers one-stop flights with one-way tickets generally priced from $120 to $410. It holds about 31% of the departures on this route, with an in-flight time of 3 hours and 15 minutes, leading to a total journey time of roughly 4 hours and 45 minutes, factoring in the layover.
- Southwest Airlines: A budget-friendly choice, Southwest Airlines delivers one-stop service with one-way fares usually ranging from $120 to $425. This airline accounts for roughly 13% of the departures on this route, maintaining an in-flight duration of 3 hours and 15 minutes and a total travel time of around 4 hours and 45 minutes, including layover time.
- United: United Airlines, a full-service provider, offers one-stop service with one-way fares that typically vary from $150 to $495. Representing about 7% of departures on this route, it features an in-flight time of 3 hours and 15 minutes and a total journey time of approximately 4 hours and 45 minutes, including layovers.
Travelers flying from Cleveland to Panama City can opt for an upgrade, as American Airlines provides first-class service on this route.
Best time to fly from Cleveland (CLE) to Panama City (ECP)
The most popular months for travelers flying from Cleveland to Panama City are March, April, and June, when peak temperatures in Panama City reach up to 81.1°F in June. If you prefer quieter travel, consider October, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 72°F. For better deals, August usually offers the lowest average one-way fare around $179. Flight availability peaks in June, with approximately 14 flights per week, making it easier to find convenient departure times. January and December have the fewest flights, with approximately 8 flights per week.
- Cheapest time to fly: August usually offers good deals with average one-way fare around $179, roughly 23% cheaper than the yearly average.
- More budget-friendly months to fly: September and October typically offer average one-way fares of around $191.
- Most flight options: June has the highest number of flights from Cleveland to Panama City, with approximately 14 flights per week, giving you more flexibility in scheduling your trip.
| Month | Temperature | Demand | Weekly Flights | Average one-way Fare |
| January | 54.1°F (12.3°C) | Average | 8 | $300 |
| February | 57.9°F (14.4°C) | Average | 9 | $237 |
| March | 62.8°F (17.1°C) | High | 13 | $262 |
| April | 68.4°F (20.2°C) | High | 10 | $234 |
| May | 75.0°F (23.9°C) | Average | 12 | $208 |
| June | 81.1°F (27.3°C) | High | 14 | $235 |
| July | 82.6°F (28.1°C) | Average | 12 | $237 |
| August | 82.8°F (28.2°C) | Average | 11 | $179 |
| September | 79.5°F (26.4°C) | Average | 10 | $186 |
| October | 72.0°F (22.2°C) | Low | 10 | $196 |
| November | 62.4°F (16.9°C) | Low | 10 | $229 |
| December | 58.1°F (14.5°C) | Low | 8 | $300 |
*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.
Alternative routes from Cleveland (CLE) to Panama City (ECP)
- Cleveland to Fort Walton Beach (CLE-VPS): Northwest Florida Regional Airport (VPS) lies approximately 46 miles from Northwest Florida Beaches International Airport (ECP). Economy one-way fares for this journey generally range from $115 to $350, influenced by the time of year and how early you book. Flights on this route usually feature a one-stop option, with common layover points at Hartsfield-Jackson Atlanta International Airport (ATL) and Charlotte-Douglas International Airport (CLT). Leading airlines operating this route include Delta and American Airlines, and first-class service is also available.
- Akron to Panama City (CAK-ECP): Akron-Canton Airport (CAK) is located about 40 miles from Hopkins International Airport (CLE). One-way economy tickets for this route typically vary from $185 to $465, depending on the season and the timing of your booking. This route is primarily served by one-stop flights, with popular layover cities including Charlotte-Douglas International Airport (CLT) and O'Hare International Airport (ORD). Major carriers on this route consist of American Airlines and United, and first-class seating is offered as well.
How to find the best prices for flights from Cleveland (CLE) to Panama City (ECP)
Getting some of the best deals on flights from Cleveland to Panama City is all about timing and flexibility. Here are some key tips to help you save:
- Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, coinciding with when most travelers make their reservations. Evening departures (6 PM-12 AM) often provide lower prices, although morning flights (5 AM-12 PM) tend to be more popular. Additionally, flying on Monday generally offers cheaper rates, while Saturday remains the most sought-after travel day.
- Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
- Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
- Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
- Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
- Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.
*Members only. Savings vary and are not available on all bundles. Select hotels.
Arriving at Northwest Florida Beaches International Airport from Hopkins International Airport
Panama City welcomes travelers from Cleveland with a range of transport options based on price, convenience, and proximity. Here's how to reach Panama City efficiently:
- Hotel transfer: Transfers offer a convenient way to reach your hotel in Panama City, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
- Car rental: Renting a car from Northwest Florida Beaches International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Northwest Florida Beaches International Airport on Expedia.
- Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
Cleveland to Panama City Flights
The cheapest times to fly from Cleveland to Panama City
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cleveland to Panama City are during the month of October. You can find some of the cheapest flights from Cleveland to Panama City with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Cleveland to Panama City
Sunday is one of the best days to book for cheap flights from Cleveland to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Cleveland to Panama City
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cleveland to Panama City in 2026. You can also book with separate airlines for your outbound and return journeys, from $134 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cleveland to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Cleveland to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently Asked Questions
How much does a flight from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) cost?
You can find cheap one-way flights from $134 and cheap return flights $267 Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) with Expedia. One-way flights generally range between $125 and $531, and roundtrip flights usually range from $326 to $1146. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) ticket fares go up or down.
*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
The cheapest month to fly from CLE to ECP is October when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
Enter CLE to ECP and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
To find a cheap flight from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
The earliest flight from Cleveland (CLE) to Panama City (ECP) usually departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in December, helping you get an early start on your trip. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
The most popular departure times for flights from Cleveland (CLE-Hopkins Intl.) to Panama City (ECP-Northwest Florida Beaches Intl.) are in the early morning, from 6am to 9am. About 48% of passengers prefer this time window. Many major carriers, including Delta, American Airlines, and Southwest Airlines, offer flights during this window. This timing works well because it allows you to arrive in Panama City with plenty of time to enjoy your day.
How long does it take to fly from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
Flights from CLE to ECP with one stop typically take around 4 hours 20 minutes, covering approximately 795 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
First class is available on flights from CLE to ECP. First class cabins are available on:
- Delta Air Lines
- American Airlines
- United Airlines
How do I earn miles on a Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight with Expedia?
It's easy to earn miles on a Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.
*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Panama City from Hopkins Intl. (CLE)?
From Hopkins Intl. (CLE), you can fly into Northwest Florida Beaches Intl. (ECP) and Tocumen Intl. (PTY) in Panama City. Some flights may connect through major hubs like O'Hare Intl. (ORD), Washington Dulles Intl. (IAD), Midway Intl. (MDW) before reaching Panama City. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) at the last minute?
Typically, booking a last minute flight from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight and hotel package?
Securing a Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
If you booked your Cleveland, OH (CLE-Hopkins Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.
Travel information
Origin airport | Cleveland Hopkins International Airport |
|---|---|
Destination airport | Northwest Florida Beaches Intl. Airport |
Distance | 795 miles away |
Airlines serving | Delta, American Airlines, United, Southwest Airlines |
Popular airline | Delta |
Roundtrip price | $267 |