Cheap Flights from Cheyenne (CYS) to Columbia (COU)

Popular airlines from Cheyenne, WY (CYS-Cheyenne Regional) to Columbia, MO (COU-Columbia Regional)

Cheap Flights from Cheyenne to Columbia (CYS-COU)

Prices were available within the past 7 days and start at for one-way flights and $464 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

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Flights from Cheyenne (CYS) to Columbia (COU)
Origin airport
Cheyenne Regional
Destination airport
Columbia Regional
Roundtrip price
$464
Distance
685 mi

Cheyenne to Columbia Flights

The cheapest times to fly from Cheyenne to Columbia

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cheyenne to Columbia are during the month of January. You can find some of the cheapest flights from Cheyenne to Columbia with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cheyenne to Columbia

Sunday is one of the best days to book for cheap flights from Cheyenne to Columbia: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cheyenne to Columbia

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cheyenne to Columbia in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cheyenne to Columbia flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cheyenne to Columbia airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Cheyenne Regional Airport (CYS) to Columbia Regional Airport (COU) cost?
Snag a cheap one-way flight or cheap return flight from $464 from Cheyenne Regional Airport (CYS) to Columbia Regional Airport (COU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Cheyenne Regional Airport (CYS) to Columbia Regional Airport (COU)?
January is the most affordable month to fly from CYS to COU. Traveling outside of peak seasons is often the key to landing a great deal.
What is the cheapest airline that flies from Cheyenne Regional Airport (CYS) to Columbia Regional Airport (COU)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest CYS to COU flight.
How many flights per day from Cheyenne Regional Airport (CYS) to Columbia Regional Airport (COU)?
There are no daily nonstop flights departing from Cheyenne Regional Airport (CYS) to Columbia Regional Airport (COU). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from CYS to COU?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* But this can vary depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cheyenne Regional Airport (CYS) to Columbia Regional Airport (COU)?
To avoid possible delays on the Cheyenne Regional Airport (CYS) to Columbia Regional Airport (COU) route, travel before 3 PM. Departures after this hour have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cheyenne Regional Airport (CYS) to Columbia Regional Airport (COU) last-minute?
Last-minute fares from CYS to COU are typically more expensive. For the best prices, start searching for flights ahead of time. That said, if your travel plans are flexible, it's possible to score a cheap fare right before your journey.
Is it cheaper to book a CYS to COU flight and hotel package?
You can save money by booking a CYS to COU flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After choosing your ideal accommodations and flights, consider adding extras including tours, car rentals and activities.
Can I cancel or change the date of my flight from Cheyenne Regional Airport (CYS) to Columbia Regional Airport (COU)?
If you reserved your CYS to COU flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

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*Available to One Key members.