$120 Cheap Flights from Des Moines (DSM) to Sioux Falls (FSD)

View $120 flight on Thu, Sep 18, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Sioux Falls Regional Airport (FSD)

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Cheap Flights from Des Moines to Sioux Falls (DSM-FSD)

Prices were available within the past 7 days and start at $120 for one-way flights and $178 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Aug 21 - Wed, Aug 27
DSM
Des Moines
FSD
Sioux Falls
$178 Roundtrip, just found
$178
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, Aug 21 from Des Moines to Sioux Falls, returning Wed, Aug 27, priced at $178 just found
Frontier Airlines
Thu, Aug 21 - Sun, Aug 31
DSM
Des Moines
FSD
Sioux Falls
$188 Roundtrip, just found
$188
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, Aug 21 from Des Moines to Sioux Falls, returning Sun, Aug 31, priced at $188 just found
Frontier Airlines
Thu, Aug 21 - Thu, Aug 28
DSM
Des Moines
FSD
Sioux Falls
$208 Roundtrip, just found
$208
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, Aug 21 from Des Moines to Sioux Falls, returning Thu, Aug 28, priced at $208 just found
Delta
Tue, Sep 9 - Tue, Sep 16
DSM
Des Moines
FSD
Sioux Falls
$287 Roundtrip, found 2 days ago
$287
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Sep 9 from Des Moines to Sioux Falls, returning Tue, Sep 16, priced at $287 found 2 days ago
Delta
Wed, Sep 10 - Tue, Sep 16
DSM
Des Moines
FSD
Sioux Falls
$292 Roundtrip, found 2 days ago
$292
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Sep 10 from Des Moines to Sioux Falls, returning Tue, Sep 16, priced at $292 found 2 days ago
Delta
Fri, Aug 22 - Wed, Sep 10
DSM
Des Moines
FSD
Sioux Falls
$297 Roundtrip, found 6 days ago
$297
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Aug 22 from Des Moines to Sioux Falls, returning Wed, Sep 10, priced at $297 found 6 days ago
Delta
Wed, Sep 10 - Sun, Sep 14
DSM
Des Moines
FSD
Sioux Falls
$302 Roundtrip, found 2 days ago
$302
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Sep 10 from Des Moines to Sioux Falls, returning Sun, Sep 14, priced at $302 found 2 days ago
Frontier Airlines
Sun, Sep 28 - Mon, Oct 13
DSM
Des Moines
FSD
Sioux Falls
$306 Roundtrip, found 6 days ago
$306
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Sun, Sep 28 from Des Moines to Sioux Falls, returning Mon, Oct 13, priced at $306 found 6 days ago
American Airlines
Sun, Aug 24 - Sun, Sep 28
DSM
Des Moines
FSD
Sioux Falls
$367 Roundtrip, found 6 hours ago
$367
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sun, Aug 24 from Des Moines to Sioux Falls, returning Sun, Sep 28, priced at $367 found 6 hours ago
United
Tue, Sep 9 - Wed, Sep 17
DSM
Des Moines
FSD
Sioux Falls
$450 Roundtrip, found 2 days ago
$450
Roundtrip
found 2 days ago
Select United flight, departing Tue, Sep 9 from Des Moines to Sioux Falls, returning Wed, Sep 17, priced at $450 found 2 days ago

Alternative airports near Sioux Falls

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Sioux Falls Regional FSD. Cheapest and Closest option available. Average driving time to city center is 6 minutes. Flights from $383
FSD
Sioux Falls Regional
CheapestClosest
Average driving time to city center6 min
Flights from $383
Flights from Des Moines (DSM) to Sioux Falls (FSD)
Origin airport
Des Moines Intl.
Destination airport
Sioux Falls Regional
Airlines serving
American Airlines, Delta, United
Roundtrip price
$178
Distance
211 mi

Des Moines to Sioux Falls Flights

The cheapest times to fly from Des Moines to Sioux Falls

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Sioux Falls are during the month of August. You can find some of the cheapest flights from Des Moines to Sioux Falls with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Sioux Falls

Sunday is one of the best days to book for cheap flights from Des Moines to Sioux Falls: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Sioux Falls

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Sioux Falls in 2025. You can also book with separate airlines for your outbound and return journeys, from $120 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Sioux Falls flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Sioux Falls airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Sioux Falls Regional Airport (FSD) cost?
Discover the latest flight deals from DSM to FSD by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from DSM to FSD?
The cheapest flights from DSM to FSD are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from DSM to FSD?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from DSM to FSD. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Des Moines Intl. Airport (DSM) to Sioux Falls Regional Airport (FSD)?
You'll need to take a flight with a layover if you're traveling from Des Moines Intl. Airport (DSM) to Sioux Falls Regional Airport (FSD). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from DSM to FSD?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can change depending on a number of factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Sioux Falls Regional Airport (FSD)?
Opt for a flight from Des Moines Intl. Airport (DSM) to Sioux Falls Regional Airport (FSD) that leaves before 3 PM to reduce the risk of cancellations and delays. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Sioux Falls Regional Airport (FSD) last-minute?
Last-minute bookings from DSM to FSD are usually more expensive. To lock in the lowest rates, start looking for flights well ahead of time. That being said, if your travel plans are flexible, you may score a cheap ticket just before your departure.
Is it cheaper to book a DSM to FSD flight and hotel package?
Compared with arranging flights and hotels separately, booking a DSM to FSD flight and hotel package with Expedia could result in significant savings. Better still, having everything in one convenient place takes the hassle out of planning your trip. Simply pick your flights and select from our wide range of stays, then tailor your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Sioux Falls Regional Airport (FSD)?
You can usually cancel or reschedule your DSM to FSD flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.