A waterfall, a river, and ruins of an old structure.

$117 Cheap Flights from Indianapolis (IND) to Sioux Falls (FSD)

View $117 flight on Fri, Sep 11, 2026Opens in a new window

Popular airlines from Indianapolis Intl. Airport (IND) to Sioux Falls Regional Airport (FSD)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Indianapolis to Sioux Falls (IND-FSD)

Prices were available within the past 7 days and start at $117 for one-way flights and $310 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Fri, Sep 25 - Sat, Sep 26
IND
Indianapolis
FSD
Sioux Falls
$310 Roundtrip, found 7 hours ago
$310
Roundtrip
found 7 hours ago
Select United flight, departing Fri, Sep 25 from Indianapolis to Sioux Falls, returning Sat, Sep 26, priced at $310 found 7 hours ago
American Airlines
Sat, Oct 10 - Tue, Oct 13
IND
Indianapolis
FSD
Sioux Falls
$311 Roundtrip, found 6 hours ago
$311
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Oct 10 from Indianapolis to Sioux Falls, returning Tue, Oct 13, priced at $311 found 6 hours ago
American Airlines
Fri, Oct 16 - Sat, Oct 24
IND
Indianapolis
FSD
Sioux Falls
$315 Roundtrip, found 6 hours ago
$315
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Oct 16 from Indianapolis to Sioux Falls, returning Sat, Oct 24, priced at $315 found 6 hours ago
American Airlines
Fri, Oct 23 - Mon, Oct 26
IND
Indianapolis
FSD
Sioux Falls
$319 Roundtrip, found 10 hours ago
$319
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Fri, Oct 23 from Indianapolis to Sioux Falls, returning Mon, Oct 26, priced at $319 found 10 hours ago
Delta
Wed, Nov 25 - Tue, Dec 1
IND
Indianapolis
FSD
Sioux Falls
$325 Roundtrip, found 2 days ago
$325
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Nov 25 from Indianapolis to Sioux Falls, returning Tue, Dec 1, priced at $325 found 2 days ago
Delta
Sat, Sep 12 - Sat, Sep 19
IND
Indianapolis
FSD
Sioux Falls
$326 Roundtrip, found 2 days ago
$326
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Sep 12 from Indianapolis to Sioux Falls, returning Sat, Sep 19, priced at $326 found 2 days ago
Delta
Fri, Sep 25 - Sat, Sep 26
IND
Indianapolis
FSD
Sioux Falls
$329 Roundtrip, found 7 hours ago
$329
Roundtrip
found 7 hours ago
Select Delta flight, departing Fri, Sep 25 from Indianapolis to Sioux Falls, returning Sat, Sep 26, priced at $329 found 7 hours ago
United
Sat, Sep 5 - Mon, Sep 7
IND
Indianapolis
FSD
Sioux Falls
$330 Roundtrip, found 2 days ago
$330
Roundtrip
found 2 days ago
Select United flight, departing Sat, Sep 5 from Indianapolis to Sioux Falls, returning Mon, Sep 7, priced at $330 found 2 days ago
Delta
Fri, Dec 11 - Mon, Dec 14
IND
Indianapolis
FSD
Sioux Falls
$333 Roundtrip, found 20 hours ago
$333
Roundtrip
found 20 hours ago
Select Delta flight, departing Fri, Dec 11 from Indianapolis to Sioux Falls, returning Mon, Dec 14, priced at $333 found 20 hours ago
United
Fri, Sep 25 - Sat, Sep 26
IND
Indianapolis
FSD
Sioux Falls
$334 Roundtrip, found 7 hours ago
$334
Roundtrip
found 7 hours ago
Select United flight, departing Fri, Sep 25 from Indianapolis to Sioux Falls, returning Sat, Sep 26, priced at $334 found 7 hours ago

Alternative airports near Sioux Falls

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Sioux Falls Regional FSD. Cheapest and Closest option available. Average driving time to city center is 6 minutes. Flights from $349
FSD
Sioux Falls Regional
CheapestClosest
Average driving time to city center6 min
Flights from $349

What you need to know for your flight from Indianapolis Intl. to Sioux Falls Regional

Indianapolis (IND) to Sioux Falls (FSD) at a glance

Embark on a journey from Indianapolis (IND) to Sioux Falls (FSD) with various airlines servicing this short domestic route. Explore options from both full-service and budget-friendly carriers to discover the best flights from Indianapolis to Sioux Falls that align with your travel needs and budget. As you plan your visit to experience the attractions and neighborhoods of Sioux Falls, be sure to check flight prices for a convenient departure from Indianapolis International Airport (IND) to Sioux Falls Regional Airport (FSD).

  • Fastest flight duration: around 3h 15m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 600 miles (970 km)
  • Flights per week: around 9 departures on average
  • Typical fares (one-way): economy tickets often range from $120–$450, depending on seasonality and how far ahead you book

Flights from Indianapolis International Airport (IND) to Sioux Falls Regional Airport (FSD)

Based on recent traveler bookings, here are the most popular airlines for flights from Indianapolis to Sioux Falls, especially favored for their one-stop services. Common layover airports include O'Hare International Airport (ORD) with an approximate 1 hour and 15-minute layover, Minneapolis-St. Paul International Airport (MSP) offering around a 1-hour layover, and Dallas-Fort Worth International Airport (DFW), also featuring a 1 hour and 15-minute layover. This variety allows you to compare prices, total travel times, and cabin classes to discover the ideal itinerary.

  • Delta: This full-service airline dominates the route, providing one-stop service. One-way tickets usually range from $120 to $465, and it accounts for around 42% of the route's departures. Expect an in-flight duration of 3 hours and 15 minutes, totaling about 4 hours and 45 minutes for the journey, including layover time.
  • American Airlines: Another full-service option, American Airlines offers one-stop flights with one-way fares typically between $120 and $380. It represents roughly 30% of departures on this route. The in-flight time is about 3 hours and 15 minutes, with a total travel duration of around 4 hours and 45 minutes, factoring in layovers.
  • United: This full-service carrier serves approximately 27% of the departures, providing one-stop flights with one-way fares generally ranging from $120 to $430. Passengers can expect an in-flight time of 3 hours and 15 minutes, leading to a total journey time of about 4 hours and 45 minutes, including layover periods.
  • Frontier Airlines: As a low-cost carrier, Frontier Airlines offers one-stop services with one-way fares typically between $120 and $175. It accounts for around 2% of departures on this route. The in-flight duration is 3 hours and 15 minutes, with an overall journey time of approximately 4 hours and 45 minutes, including any layover.

Travelers flying from Indianapolis to Sioux Falls have the option to upgrade their experience, with Delta providing both first class and premium economy service on this route.

Best time to fly from Indianapolis (IND) to Sioux Falls (FSD)

The most popular months for travelers flying from Indianapolis to Sioux Falls are April, July, and October, when peak temperatures in Sioux Falls reach up to 73.2°F in July. If you prefer quieter travel, consider November, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 36.1°F. For better deals, January usually offers the lowest average one-way fare around $204. Flight availability peaks in May and October, with approximately 11 flights per week, making it easier to find convenient departure times. February, March, June, September, and December have the fewest flights, with approximately 8 flights per week.

  • Cheapest time to fly: January usually offers good deals with average one-way fare around $204, roughly 12% cheaper than the yearly average.
  • More budget-friendly months to fly: April, July, and May typically offer average one-way fares of around $211.
  • Most flight options: May and October have the highest number of flights from Indianapolis to Sioux Falls, with approximately 11 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January16.9°F (-8.4°C)Average9$204
February19.2°F (-7.1°C)Average8$223
March34.9°F (1.6°C)Average8$249
April46.2°F (7.9°C)Slightly High10$209
May58.6°F (14.8°C)Average11$213
June69.4°F (20.8°C)Slightly Low8$247
July73.2°F (22.9°C)Slightly High10$211
August71.4°F (21.9°C)Average10$228
September64.6°F (18.1°C)Average8$278
October49.3°F (9.6°C)Slightly High11$256
November36.1°F (2.3°C)Slightly Low9$226
December22.8°F (-5.1°C)Slightly Low8$239

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Indianapolis (IND) to Sioux Falls (FSD)

  • Anderson to Sioux Falls (AID-FSD): Located approximately 46 miles from Indianapolis International Airport (IND), Anderson Municipal Airport (AID) provides convenient access.
  • Lafayette to Sioux Falls (LAF-FSD): Purdue University Airport (LAF) is roughly 59 miles away from Indianapolis International Airport (IND), making it another viable option.

How to find the best prices for flights from Indianapolis (IND) to Sioux Falls (FSD)

Getting some of the best deals on flights from Indianapolis to Sioux Falls is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking at least two months in advance, although most travelers book between two to eight weeks ahead. Afternoon departures from 12pm to 6pm often provide lower prices, while morning flights from 5am to 12pm are the most popular. Additionally, flying on Tuesday can lead to cheaper fares, but Thursday remains the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Sioux Falls hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Sioux Falls Regional Airport from Indianapolis International Airport

Sioux Falls welcomes travelers from Indianapolis with a range of transport options based on price, convenience, and proximity. Here's how to reach Sioux Falls efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Sioux Falls, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Sioux Falls Regional Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Sioux Falls Regional Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) cost?
You can find cheap one-way flights from $117 and cheap return flights from $310 Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) with Expedia. One-way flights usually range from $125 to $603, and return flights typically cost between $346 and $1084. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
January is the cheapest month to fly from Indianapolis (IND) to Sioux Falls (FSD), with average round-trip fares around $338. This fare is about 16% lower than the average price throughout the year, as January typically sees a drop in travel demand after the holiday season. Other cheap months to fly from Indianapolis to Sioux Falls include April and August.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
Enter IND to FSD and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
Frontier Airlines is one of the cheapest airlines offering connecting flights from Indianapolis, IN (IND) to Sioux Falls, SD (FSD), with round-trip tickets starting from around $168. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
To find a cheap flight from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
When flying from Indianapolis, IN (IND) to Sioux Falls, SD (FSD), January and April are the best months to consider. You can find return flights for around $338 in January, which is a quieter travel time. April also offers good prices, making it a great time to visit as spring begins.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
The earliest flight from Indianapolis (IND) to Sioux Falls, SD (FSD) usually leaves at around 5:00 AM, operated by American Airlines. This early departure can help you make the most of your day upon arrival. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
For flights from Indianapolis (IND) to Sioux Falls (FSD), the most popular departure times are in the early morning, from 6am to 9am. About 33% of passengers choose this time window. Major carriers like United Airlines, American Airlines, and Delta operate flights during this period. This timing is favored as it allows you to arrive in Sioux Falls with ample time to start your day.
How long does it take to fly from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
A flight from IND to FSD with a layover takes around 5 hours 50 minutes, with the route covering approximately 601 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
First class seats are offered on the IND to FSD route. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight with Expedia?
It's easy to earn miles on a Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Sioux Falls from Indianapolis Intl. (IND)?
From Indianapolis Intl. (IND), you can fly into Sioux Falls Regional (FSD) to reach Sioux Falls. Some flights may connect through major hubs like O'Hare Intl. (ORD), Washington Dulles Intl. (IAD), George Bush Intercontinental (IAH) before reaching Sioux Falls. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) at the last minute?
Typically, booking a last minute flight from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight and hotel package?
Securing a Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) Sioux Falls Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
If you booked your Indianapolis, IN (IND-Indianapolis Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Indianapolis Intl.
Destination airport
Sioux Falls Regional
Airlines serving
American Airlines, Delta, United
Roundtrip price
$310
Distance
600 mi

Book with confidence

Indianapolis to Sioux Falls Flights

The cheapest times to fly from Indianapolis to Sioux Falls

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Indianapolis to Sioux Falls are during the month of September. You can find some of the cheapest flights from Indianapolis to Sioux Falls with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Indianapolis to Sioux Falls

Sunday is one of the best days to book for cheap flights from Indianapolis to Sioux Falls: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Indianapolis to Sioux Falls

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Indianapolis to Sioux Falls in 2026. You can also book with separate airlines for your outbound and return journeys, from $117 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Indianapolis to Sioux Falls flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Indianapolis to Sioux Falls airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Indianapolis to Sioux Falls Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

Explore a world of travel with Expedia