A coastal cityscape with a long beach, clear turquoise waters, and high-rise buildings.

$284 Cheap Flights from Lexington (LEX) to Panama City (ECP)

View $284 flight on Sat, Feb 6, 2027Opens in a new window

Popular airlines from Blue Grass Airport (LEX) to Northwest Florida Beaches Intl. Airport (ECP)

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Cheap Flights from Lexington to Panama City (LEX-ECP)

Prices were available within the past 7 days and start at $284 for one-way flights and $339 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Fri, Feb 19 - Tue, Feb 23
LEX
Lexington
ECP
Panama City
$339 Roundtrip, found 5 days ago
$339
Roundtrip
found 5 days ago
Select United flight, departing Fri, Feb 19 from Lexington to Panama City, returning Tue, Feb 23, priced at $339 found 5 days ago
United
Sat, Nov 28 - Sat, Dec 12
LEX
Lexington
ECP
Panama City
$385 Roundtrip, found 2 days ago
$385
Roundtrip
found 2 days ago
Select United flight, departing Sat, Nov 28 from Lexington to Panama City, returning Sat, Dec 12, priced at $385 found 2 days ago
American Airlines
Sat, Oct 17 - Sat, Oct 24
LEX
Lexington
ECP
Panama City
$387 Roundtrip, found 10 hours ago
$387
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Sat, Oct 17 from Lexington to Panama City, returning Sat, Oct 24, priced at $387 found 10 hours ago
United
Sat, Nov 28 - Sat, Dec 12
LEX
Lexington
ECP
Panama City
$393 Roundtrip, found 2 days ago
$393
Roundtrip
found 2 days ago
Select United flight, departing Sat, Nov 28 from Lexington to Panama City, returning Sat, Dec 12, priced at $393 found 2 days ago
American Airlines
Wed, Sep 30 - Wed, Oct 7
LEX
Lexington
ECP
Panama City
$412 Roundtrip, found 5 days ago
$412
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Sep 30 from Lexington to Panama City, returning Wed, Oct 7, priced at $412 found 5 days ago
United
Fri, Feb 19 - Tue, Feb 23
LEX
Lexington
ECP
Panama City
$419 Roundtrip, found 5 days ago
$419
Roundtrip
found 5 days ago
Select United flight, departing Fri, Feb 19 from Lexington to Panama City, returning Tue, Feb 23, priced at $419 found 5 days ago
American Airlines
Sat, Oct 17 - Thu, Oct 22
LEX
Lexington
ECP
Panama City
$422 Roundtrip, found 9 hours ago
$422
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sat, Oct 17 from Lexington to Panama City, returning Thu, Oct 22, priced at $422 found 9 hours ago
American Airlines
Fri, May 21 - Wed, May 26
LEX
Lexington
ECP
Panama City
$438 Roundtrip, found 10 hours ago
$438
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Fri, May 21 from Lexington to Panama City, returning Wed, May 26, priced at $438 found 10 hours ago
Delta
Sat, Oct 17 - Wed, Oct 21
LEX
Lexington
ECP
Panama City
$441 Roundtrip, found 20 hours ago
$441
Roundtrip
found 20 hours ago
Select Delta flight, departing Sat, Oct 17 from Lexington to Panama City, returning Wed, Oct 21, priced at $441 found 20 hours ago
United
Sat, Oct 17 - Sat, Oct 24
LEX
Lexington
ECP
Panama City
$442 Roundtrip, found 10 hours ago
$442
Roundtrip
found 10 hours ago
Select United flight, departing Sat, Oct 17 from Lexington to Panama City, returning Sat, Oct 24, priced at $442 found 10 hours ago

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Northwest Florida Beaches Intl. ECP. Cheapest and Closest option available. Average driving time to city center is 35 minutes. Flights from $745
ECP
Northwest Florida Beaches Intl.
CheapestClosest
Average driving time to city center35 min
Flights from $745

Find the cheapest month to fly from Lexington (LEX) to Panama City (ECP)

January is typically the cheapest month to fly

From $198 - $466 per traveler.

What you need to know for your flight from Blue Grass to Northwest Florida Beaches Intl.

Lexington (LEX) to Panama City (ECP) at a glance

Explore the diverse options for Lexington to Panama City flights on this domestic short-haul route. Whether you're looking for cheap flights from Lexington or a full-service experience, you can compare various airlines to find the itinerary that best suits your budget and schedule. Discover the key details for flights from Blue Grass Airport (LEX) to Northwest Florida Beaches International Airport (ECP) as you plan your visit to Panama City's renowned attractions and neighborhoods.

  • Fastest flight duration: around 2h 45m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 500 miles (800 km)
  • Flights per week: around 8 departures on average
  • Typical fares (one-way): economy tickets often range from $125–$355, depending on seasonality and how far ahead you book

Flights from Blue Grass Airport (LEX) to Northwest Florida Beaches International Airport (ECP)

Based on recent traveler bookings, here are the top airlines favored for flights from Lexington to Panama City, particularly for one-stop services. Common layover locations include Hartsfield-Jackson Atlanta International Airport (ATL) with approximately a 1-hour layover, Charlotte-Douglas International Airport (CLT) also around 1 hour, and O'Hare International Airport (ORD) with about a 3-hour layover. These options provide the flexibility to compare fares, total travel times, and cabin classes to help you secure the ideal itinerary.

  • Delta: As a leading full-service airline, Delta provides one-stop flights with one-way ticket prices usually falling between $125 and $405. This carrier represents around 61% of departures on this route, featuring an in-flight duration of 2 hours and 45 minutes, with a total travel time nearing 4 hours, including layover.
  • American Airlines: Another full-service option, American Airlines offers one-stop services with one-way fares generally ranging from $125 to $360. This airline accounts for approximately 36% of departures on the route, with an in-flight time of 2 hours and 45 minutes and an overall journey time close to 4 hours, inclusive of a layover.
  • United: United Airlines, also a full-service provider, features one-stop flights with one-way fares typically between $185 and $280. It constitutes about 3% of the departures for this route, offering an in-flight duration of 2 hours and 45 minutes, while the total trip time is around 4 hours, factoring in the layover.

Alternative route from Lexington (LEX) to Panama City (ECP)

  • Lexington to Fort Walton Beach (LEX-VPS): Northwest Florida Regional Airport (VPS) is located approximately 46 miles from Northwest Florida Beaches International Airport (ECP). One-way economy fares for this route generally fall between $130 and $430, influenced by the season and the timing of your booking. Typically, flights on this route involve one stop, with common layover points being Hartsfield-Jackson Atlanta International Airport (ATL) and Charlotte-Douglas International Airport (CLT). Major airlines serving this route include Delta and American Airlines, with first-class service also available.

How to find the best prices for flights from Lexington (LEX) to Panama City (ECP)

Getting some of the best deals on flights from Lexington to Panama City is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are generally available when booking at least two months in advance, although most travelers tend to book between two to eight weeks ahead. Evening departures from 6 PM to 12 AM often offer lower prices, while morning flights from 5 AM to 12 PM are the most popular. Additionally, flying on Sunday provides both cheaper prices and is the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Northwest Florida Beaches International Airport from Blue Grass Airport

Panama City welcomes travelers from Lexington with a range of transport options based on price, convenience, and proximity. Here's how to reach Panama City efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Panama City, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Northwest Florida Beaches International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Northwest Florida Beaches International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) cost?
You can find cheap one-way flights from $284 and cheap return flights from $339 Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) with Expedia. One-way flights generally range between $223 and $665, and roundtrip flights usually range from $369 to $1241. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
August is the cheapest month to fly from Lexington (LEX) to Panama City (ECP), with average round-trip fares around $282. This is about 35% lower than the average price throughout the year, as demand tends to drop during the late summer. Other economical months to consider are May and September.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
Enter LEX to ECP and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
Delta is one of the cheapest airlines offering connecting flights from Lexington (LEX) to Panama City (ECP) with a layover in Hartsfield-Jackson Atlanta Intl. (ATL), starting from around $248 for a round-trip ticket. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
To find a cheap flight from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
The best time to fly from Lexington, KY (LEX) to Panama City, FL (ECP) is typically in August or September. During these months, you can find return flights at around $282, making them the cheapest options. August and September are ideal because they fall just after the summer peak travel season, allowing for lower fares and a more relaxed travel experience.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
The earliest flight from Lexington (LEX) to Panama City (ECP) typically departs at around 5:00 AM, operated by American Airlines. This is a seasonal service active in August, and an early departure can help you maximize your beach time in Florida. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
The most popular departure times for flights from Blue Grass Airport (LEX) to Northwest Florida Beaches International (ECP) are in the early morning, from 6am to 9am. About 39% of passengers prefer this time window. Many major carriers, including American Airlines, Delta Airlines and United Airlines, offer flights during this window. This timing works well because it lets you arrive in Florida early, giving you a full day to enjoy the beach.
How long does it take to fly from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
Flying from LEX to ECP with a connection usually takes about 6 hours 30 minutes, traveling roughly 535 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
First class is available on flights from LEX to ECP. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight with Expedia?
It's easy to earn miles on a Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Panama City from Blue Grass (LEX)?
From Blue Grass (LEX), you can fly into Northwest Florida Beaches Intl. (ECP) and Tocumen Intl. (PTY) in Panama City. Some flights may connect through major hubs like O'Hare Intl. (ORD), Philadelphia Intl. (PHL), Ronald Reagan Washington National (DCA) before reaching Panama City. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) at the last minute?
Typically, booking a last minute flight from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight and hotel package?
Securing a Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
If you booked your Lexington, KY (LEX-Blue Grass) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Blue Grass
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$338
Distance
535 mi

Book with confidence

Lexington to Panama City Flights

The cheapest times to fly from Lexington to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lexington to Panama City are during the month of February. You can find some of the cheapest flights from Lexington to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lexington to Panama City

Sunday is one of the best days to book for cheap flights from Lexington to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lexington to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lexington to Panama City in 2026. You can also book with separate airlines for your outbound and return journeys, from $284 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lexington to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lexington to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Lexington to Panama City Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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