$405 Cheap Flights from Monroe (MLU) to Columbia (COU)

View $405 flight on Tue, Mar 24, 2026Opens in a new window

Popular airlines from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional)

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Cheap Flights from Monroe to Columbia (MLU-COU)

Prices were available within the past 7 days and start at $405 for one-way flights and $530 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Apr 23 - Sat, Apr 25
MLU
Monroe
COU
Columbia
$530 Roundtrip, found 4 days ago
$530
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 23 from Monroe to Columbia, returning Sat, Apr 25, priced at $530 found 4 days ago
American Airlines
Thu, Apr 23 - Sat, Apr 25
MLU
Monroe
COU
Columbia
$565 Roundtrip, found 4 days ago
$565
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 23 from Monroe to Columbia, returning Sat, Apr 25, priced at $565 found 4 days ago
American Airlines
Thu, Apr 23 - Sat, Apr 25
MLU
Monroe
COU
Columbia
$568 Roundtrip, found 4 days ago
$568
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 23 from Monroe to Columbia, returning Sat, Apr 25, priced at $568 found 4 days ago
American Airlines
Thu, Apr 23 - Sat, Apr 25
MLU
Monroe
COU
Columbia
$595 Roundtrip, found 4 days ago
$595
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 23 from Monroe to Columbia, returning Sat, Apr 25, priced at $595 found 4 days ago
American Airlines
Fri, Jun 5 - Tue, Jun 9
MLU
Monroe
COU
Columbia
$606 Roundtrip, found 4 days ago
$606
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Jun 5 from Monroe to Columbia, returning Tue, Jun 9, priced at $606 found 4 days ago
American Airlines
Thu, Apr 23 - Sat, Apr 25
MLU
Monroe
COU
Columbia
$621 Roundtrip, found 4 days ago
$621
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 23 from Monroe to Columbia, returning Sat, Apr 25, priced at $621 found 4 days ago
American Airlines
Thu, Apr 23 - Sat, Apr 25
MLU
Monroe
COU
Columbia
$626 Roundtrip, found 4 days ago
$626
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 23 from Monroe to Columbia, returning Sat, Apr 25, priced at $626 found 4 days ago
American Airlines
Thu, Apr 23 - Sat, Apr 25
MLU
Monroe
COU
Columbia
$630 Roundtrip, found 4 days ago
$630
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 23 from Monroe to Columbia, returning Sat, Apr 25, priced at $630 found 4 days ago
American Airlines
Thu, Apr 23 - Sat, Apr 25
MLU
Monroe
COU
Columbia
$652 Roundtrip, found 4 days ago
$652
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 23 from Monroe to Columbia, returning Sat, Apr 25, priced at $652 found 4 days ago
American Airlines
Thu, Apr 23 - Sat, Apr 25
MLU
Monroe
COU
Columbia
$654 Roundtrip, found 4 days ago
$654
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 23 from Monroe to Columbia, returning Sat, Apr 25, priced at $654 found 4 days ago

Frequently asked questions

How much does a flight from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional) cost?
You can find cheap one-way flights from $405 and cheap return flights from $530 Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional) with Expedia. One-way flights usually range from $421 to $526, and return flights typically cost between $474 and $1434. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional)?
The cheapest month to fly from MLU to COU is April when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional)?
Enter MLU to COU and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional)?
American Airlines is one of the cheapest airlines offering connecting flights from Monroe, LA (MLU) to Columbia, MO (COU), with round-trip tickets starting from around $466. This flight has a layover in Dallas-Fort Worth Intl. (DFW). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional)?
To find a cheap flight from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional)?
The earliest flight from Monroe Regional (MLU) to Columbia Regional (COU) usually departs at around 5:30 AM, operated by American Airlines. This service is seasonal, active in November and December, and an early start can give you a full day to enjoy Columbia. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional)?
The most popular departure times for flights from Monroe Regional (MLU) to Columbia Regional (COU) are from 3am to 6am. About 66% of passengers prefer this time window. Many major carriers, including American Airlines, offer flights during this window. This timing works well because it allows travelers to start their day early and arrive in Columbia in time for morning activities.
How long does it take to fly from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional)?
Flights from MLU to COU with one stop typically take around 6 hours 20 minutes, covering approximately 436 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional)?
First class seats are offered on the MLU to COU route with American Airlines.
How do I earn miles on a Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional) flight with Expedia?
It's easy to earn miles on a Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Columbia from Monroe Regional (MLU)?
From Monroe Regional (MLU), you can fly into Columbia Metropolitan (CAE) and Columbia Regional (COU) in Columbia. Some flights may connect through major hubs like Dallas-Fort Worth Intl. (DFW), Hartsfield-Jackson Atlanta Intl. (ATL) before reaching Columbia. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional) at the last minute?
Typically, booking a last minute flight from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional) flight and hotel package?
Securing a Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional) Columbia Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional)?
If you booked your Monroe, LA (MLU-Monroe Regional) to Columbia, MO (COU-Columbia Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Monroe Regional
Destination airport
Columbia Regional
Roundtrip price
$529
Distance
435 mi

Book with confidence

Monroe to Columbia Flights

The cheapest times to fly from Monroe to Columbia

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Monroe to Columbia are during the month of April. You can find some of the cheapest flights from Monroe to Columbia with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Monroe to Columbia

Sunday is one of the best days to book for cheap flights from Monroe to Columbia: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Monroe to Columbia

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Monroe to Columbia in 2026. You can also book with separate airlines for your outbound and return journeys, from $405 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Monroe to Columbia flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Monroe to Columbia airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Monroe to Columbia Flights

*Flight schedules are subject to change.

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*Available to One Key members.