$363 Cheap Flights from Myrtle Beach (MYR) to Guayaquil (GYE)

View $363 flight on Tue, Sep 16, 2025Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE)

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Cheap Flights from Myrtle Beach to Guayaquil (MYR-GYE)

Prices were available within the past 7 days and start at $363 for one-way flights and $551 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Sep 23 - Mon, Oct 6
MYR
Myrtle Beach
GYE
Guayaquil
$551 Roundtrip, found 1 day ago
$551
Roundtrip
found 1 day ago
Select United flight, departing Tue, Sep 23 from Myrtle Beach to Guayaquil, returning Mon, Oct 6, priced at $551 found 1 day ago
Delta
Mon, Oct 6 - Tue, Oct 21
MYR
Myrtle Beach
GYE
Guayaquil
$554 Roundtrip, found 3 days ago
$554
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Oct 6 from Myrtle Beach to Guayaquil, returning Tue, Oct 21, priced at $554 found 3 days ago
Delta
Sun, Aug 24 - Mon, Sep 8
MYR
Myrtle Beach
GYE
Guayaquil
$559 Roundtrip, found 1 day ago
$559
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Aug 24 from Myrtle Beach to Guayaquil, returning Mon, Sep 8, priced at $559 found 1 day ago
Delta
Sun, Oct 5 - Tue, Oct 21
MYR
Myrtle Beach
GYE
Guayaquil
$561 Roundtrip, found 3 days ago
$561
Roundtrip
found 3 days ago
Select Delta flight, departing Sun, Oct 5 from Myrtle Beach to Guayaquil, returning Tue, Oct 21, priced at $561 found 3 days ago
United
Wed, Nov 5 - Wed, Nov 26
MYR
Myrtle Beach
GYE
Guayaquil
$561 Roundtrip, found 3 days ago
$561
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 5 from Myrtle Beach to Guayaquil, returning Wed, Nov 26, priced at $561 found 3 days ago
Delta
Mon, Sep 15 - Tue, Sep 30
MYR
Myrtle Beach
GYE
Guayaquil
$570 Roundtrip, found 3 days ago
$570
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Sep 15 from Myrtle Beach to Guayaquil, returning Tue, Sep 30, priced at $570 found 3 days ago
Delta
Mon, Sep 15 - Wed, Oct 1
MYR
Myrtle Beach
GYE
Guayaquil
$576 Roundtrip, found 3 days ago
$576
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Sep 15 from Myrtle Beach to Guayaquil, returning Wed, Oct 1, priced at $576 found 3 days ago
Delta
Sat, Sep 27 - Tue, Oct 7
MYR
Myrtle Beach
GYE
Guayaquil
$579 Roundtrip, found 3 days ago
$579
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Sep 27 from Myrtle Beach to Guayaquil, returning Tue, Oct 7, priced at $579 found 3 days ago
American Airlines
Sat, Oct 18 - Mon, Nov 3
MYR
Myrtle Beach
GYE
Guayaquil
$634 Roundtrip, found 6 days ago
$634
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Oct 18 from Myrtle Beach to Guayaquil, returning Mon, Nov 3, priced at $634 found 6 days ago
LATAM Airlines Group
Wed, Oct 8 - Mon, Oct 27
MYR
Myrtle Beach
GYE
Guayaquil
$698 Roundtrip, found 3 days ago
$698
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Wed, Oct 8 from Myrtle Beach to Guayaquil, returning Mon, Oct 27, priced at $698 found 3 days ago

Alternative airports near Guayaquil

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Joaquin de Olmedo Intl. GYE. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $737
GYE
Jose Joaquin de Olmedo Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $737
Flights from Myrtle Beach (MYR) to Guayaquil (GYE)
Origin airport
Myrtle Beach Intl.
Destination airport
Jose Joaquin de Olmedo Intl.
Airlines serving
American Airlines, Delta, LATAM Airlines Group, United
Roundtrip price
$551
Distance
2476 mi

Myrtle Beach to Guayaquil Flights

The cheapest times to fly from Myrtle Beach to Guayaquil

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Guayaquil are during the month of September. You can find some of the cheapest flights from Myrtle Beach to Guayaquil with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Guayaquil

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Guayaquil: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Guayaquil

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Guayaquil in 2025. You can also book with separate airlines for your outbound and return journeys, from $363 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Guayaquil flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Guayaquil airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE) cost?
Discover the latest flight deals from MYR to GYE by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from MYR to GYE?
The cheapest flights from MYR to GYE are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from MYR to GYE?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from MYR to GYE. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
You'll need to hop on a flight with a layover if you're traveling from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from MYR to GYE?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Opt for a flight from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE) that takes off before 3 PM to reduce the likelihood of delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE) last-minute?
Last-minute bookings from MYR to GYE are generally more expensive. For the best prices, start looking for flights early. That being said, if you're flexible with your travel plans, you may land a cheap fare right before your journey.
Is it cheaper to book a MYR to GYE flight and hotel package?
Compared with arranging flights and hotels separately, booking a MYR to GYE flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one easy place will take the hassle out of planning your trip. Just pick your flights and choose from our wide range of stays, then customize your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Typically, you can modify or cancel your MYR to GYE flight. However, additional fees may apply, especially if you made your booking over 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you want further information, head to our Customer Service portal.

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*Available to One Key members.