$681 Cheap Flights from Prague (PRG) to Knoxville (TYS)

View $681 flight on Sat, Aug 30, 2025Opens in a new window

Popular airlines from Vaclav Havel Airport (PRG) to McGhee Tyson Airport (TYS)

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Cheap Flights from Prague to Knoxville (PRG-TYS)

Prices were available within the past 7 days and start at $681 for one-way flights and $850 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

British Airways
Tue, Sep 2 - Mon, Sep 8
PRG
Prague
TYS
Knoxville
$850 Roundtrip, found 2 days ago
$850
Roundtrip
found 2 days ago
Select British Airways flight, departing Tue, Sep 2 from Prague to Knoxville, returning Mon, Sep 8, priced at $850 found 2 days ago
British Airways
Tue, Sep 2 - Mon, Sep 8
PRG
Prague
TYS
Knoxville
$874 Roundtrip, found 2 days ago
$874
Roundtrip
found 2 days ago
Select British Airways flight, departing Tue, Sep 2 from Prague to Knoxville, returning Mon, Sep 8, priced at $874 found 2 days ago
British Airways
Tue, Sep 2 - Mon, Sep 8
PRG
Prague
TYS
Knoxville
$876 Roundtrip, found 2 days ago
$876
Roundtrip
found 2 days ago
Select British Airways flight, departing Tue, Sep 2 from Prague to Knoxville, returning Mon, Sep 8, priced at $876 found 2 days ago
British Airways
Tue, Sep 2 - Mon, Sep 8
PRG
Prague
TYS
Knoxville
$903 Roundtrip, found 2 days ago
$903
Roundtrip
found 2 days ago
Select British Airways flight, departing Tue, Sep 2 from Prague to Knoxville, returning Mon, Sep 8, priced at $903 found 2 days ago
Lufthansa
Tue, Sep 2 - Mon, Sep 8
PRG
Prague
TYS
Knoxville
$932 Roundtrip, found 2 days ago
$932
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Tue, Sep 2 from Prague to Knoxville, returning Mon, Sep 8, priced at $932 found 2 days ago
Lufthansa
Tue, Sep 2 - Mon, Sep 8
PRG
Prague
TYS
Knoxville
$935 Roundtrip, found 2 days ago
$935
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Tue, Sep 2 from Prague to Knoxville, returning Mon, Sep 8, priced at $935 found 2 days ago
Lufthansa
Sun, Aug 24 - Sat, Dec 6
PRG
Prague
TYS
Knoxville
$937 Roundtrip, found 6 days ago
$937
Roundtrip
found 6 days ago
Select Lufthansa flight, departing Sun, Aug 24 from Prague to Knoxville, returning Sat, Dec 6, priced at $937 found 6 days ago
Brussels Airlines
Tue, Sep 2 - Mon, Sep 8
PRG
Prague
TYS
Knoxville
$940 Roundtrip, found 2 days ago
$940
Roundtrip
found 2 days ago
Select Brussels Airlines flight, departing Tue, Sep 2 from Prague to Knoxville, returning Mon, Sep 8, priced at $940 found 2 days ago
United
Sun, Aug 24 - Sat, Dec 6
PRG
Prague
TYS
Knoxville
$950 Roundtrip, found 6 days ago
$950
Roundtrip
found 6 days ago
Select United flight, departing Sun, Aug 24 from Prague to Knoxville, returning Sat, Dec 6, priced at $950 found 6 days ago
American Airlines
Sun, Aug 24 - Sat, Dec 6
PRG
Prague
TYS
Knoxville
$964 Roundtrip, found 6 days ago
$964
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, Aug 24 from Prague to Knoxville, returning Sat, Dec 6, priced at $964 found 6 days ago
Flights from Prague (PRG) to Knoxville (TYS)
Origin airport
Vaclav Havel
Destination airport
McGhee Tyson
Roundtrip price
$850
Distance
4699 mi

Prague to Knoxville Flights

The cheapest times to fly from Prague to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Prague to Knoxville are during the month of September. You can find some of the cheapest flights from Prague to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Prague to Knoxville

Sunday is one of the best days to book for cheap flights from Prague to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Prague to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Prague to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $681 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Prague to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Prague to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Vaclav Havel Airport (PRG) to McGhee Tyson Airport (TYS) cost?
Discover the latest flight deals from PRG to TYS by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from PRG to TYS?
The cheapest flights from PRG to TYS are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from PRG to TYS?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from PRG to TYS. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Vaclav Havel Airport (PRG) to McGhee Tyson Airport (TYS)?
You'll have to catch a flight with a layover if you're traveling from Vaclav Havel Airport (PRG) to McGhee Tyson Airport (TYS). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from PRG to TYS?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can change based on a number of factors, including the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Vaclav Havel Airport (PRG) to McGhee Tyson Airport (TYS)?
Opt for a flight from Vaclav Havel Airport (PRG) to McGhee Tyson Airport (TYS) that leaves before 3 PM to reduce the risk of cancellations and delays. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Vaclav Havel Airport (PRG) to McGhee Tyson Airport (TYS) last-minute?
Holding off until right before your break to book a ticket from PRG to TYS often results in higher prices. While you might find some last-minute offers, there's no guarantee. Keep your travel schedule open for a better chance of snagging a bargain.
Is it cheaper to book a PRG to TYS flight and hotel package?
You can save money by securing a PRG to TYS flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. Once you've selected your ideal flights and accommodations, consider adding extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Vaclav Havel Airport (PRG) to McGhee Tyson Airport (TYS)?
In most instances, you're able to reschedule or cancel your PRG to TYS flight. However, additional fees may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's fees and rules on flight changes, or if you want more details, head to our Customer Service portal.

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*Available to One Key members.