$207 Cheap Flights from Fort Myers (RSW) to Sioux Falls (FSD)

View $207 flight on Thu, Feb 19, 2026Opens in a new window

Popular airlines from Southwest Florida Intl. Airport (RSW) to Sioux Falls Regional Airport (FSD)

Cheap Flights from Fort Myers to Sioux Falls (RSW-FSD)

Prices were available within the past 7 days and start at $207 for one-way flights and $259 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sat, Dec 6 - Tue, Dec 16
RSW
Fort Myers
FSD
Sioux Falls
$259 Roundtrip, just found
$259
Roundtrip
just found
Select Delta flight, departing Sat, Dec 6 from Fort Myers to Sioux Falls, returning Tue, Dec 16, priced at $259 just found
United
Wed, Mar 11 - Mon, Mar 16
RSW
Fort Myers
FSD
Sioux Falls
$259 Roundtrip, found 6 hours ago
$259
Roundtrip
found 6 hours ago
Select United flight, departing Wed, Mar 11 from Fort Myers to Sioux Falls, returning Mon, Mar 16, priced at $259 found 6 hours ago
Delta
Thu, Dec 4 - Tue, Dec 16
RSW
Fort Myers
FSD
Sioux Falls
$264 Roundtrip, just found
$264
Roundtrip
just found
Select Delta flight, departing Thu, Dec 4 from Fort Myers to Sioux Falls, returning Tue, Dec 16, priced at $264 just found
Delta
Sat, Dec 6 - Wed, Dec 17
RSW
Fort Myers
FSD
Sioux Falls
$264 Roundtrip, just found
$264
Roundtrip
just found
Select Delta flight, departing Sat, Dec 6 from Fort Myers to Sioux Falls, returning Wed, Dec 17, priced at $264 just found
American Airlines
Thu, Dec 11 - Sun, Dec 14
RSW
Fort Myers
FSD
Sioux Falls
$269 Roundtrip, found 1 day ago
$269
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Dec 11 from Fort Myers to Sioux Falls, returning Sun, Dec 14, priced at $269 found 1 day ago
Delta
Thu, Dec 4 - Wed, Dec 17
RSW
Fort Myers
FSD
Sioux Falls
$269 Roundtrip, just found
$269
Roundtrip
just found
Select Delta flight, departing Thu, Dec 4 from Fort Myers to Sioux Falls, returning Wed, Dec 17, priced at $269 just found
Delta
Sun, Dec 7 - Sun, Dec 14
RSW
Fort Myers
FSD
Sioux Falls
$274 Roundtrip, just found
$274
Roundtrip
just found
Select Delta flight, departing Sun, Dec 7 from Fort Myers to Sioux Falls, returning Sun, Dec 14, priced at $274 just found
United
Thu, Feb 19 - Sun, Feb 22
RSW
Fort Myers
FSD
Sioux Falls
$277 Roundtrip, found 8 hours ago
$277
Roundtrip
found 8 hours ago
Select United flight, departing Thu, Feb 19 from Fort Myers to Sioux Falls, returning Sun, Feb 22, priced at $277 found 8 hours ago
United
Wed, Mar 11 - Mon, Mar 16
RSW
Fort Myers
FSD
Sioux Falls
$281 Roundtrip, found 6 hours ago
$281
Roundtrip
found 6 hours ago
Select United flight, departing Wed, Mar 11 from Fort Myers to Sioux Falls, returning Mon, Mar 16, priced at $281 found 6 hours ago
Frontier Airlines
Sat, Feb 14 - Fri, Feb 27
RSW
Fort Myers
FSD
Sioux Falls
$342 Roundtrip, found 9 hours ago
$342
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Sat, Feb 14 from Fort Myers to Sioux Falls, returning Fri, Feb 27, priced at $342 found 9 hours ago

Find the cheapest month to fly from Fort Myers (RSW) to Sioux Falls (FSD)

May is typically the cheapest month to fly

From $213 - $678 per traveler.

Alternative airports near Sioux Falls

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Sioux Falls Regional FSD. Cheapest and Closest option available. Average driving time to city center is 6 minutes. Flights from $329
FSD
Sioux Falls Regional
CheapestClosest
Average driving time to city center6 min
Flights from $329
Flights from Fort Myers (RSW) to Sioux Falls (FSD)
Origin airport
Southwest Florida Intl.
Destination airport
Sioux Falls Regional
Airlines serving
American Airlines, Delta, United
Roundtrip price
$258
Distance
1446 mi

Fort Myers to Sioux Falls Flights

The cheapest times to fly from Fort Myers to Sioux Falls

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Myers to Sioux Falls are during the month of December. You can find some of the cheapest flights from Fort Myers to Sioux Falls with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Fort Myers to Sioux Falls

Sunday is one of the best days to book for cheap flights from Fort Myers to Sioux Falls: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Fort Myers to Sioux Falls

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Myers to Sioux Falls in 2025. You can also book with separate airlines for your outbound and return journeys, from $207 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Myers to Sioux Falls flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Myers to Sioux Falls airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Southwest Florida Intl. Airport (RSW) to Sioux Falls Regional Airport (FSD) cost?
Snag a cheap one-way flight from $207 or cheap return flight from $259 from Southwest Florida Intl. Airport (RSW) to Sioux Falls Regional Airport (FSD) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Southwest Florida Intl. Airport (RSW) to Sioux Falls Regional Airport (FSD)?
The cheapest month to fly from RSW to FSD is December, when there's less demand. Off-peak season is often when airlines offer lower prices between these airports.
Which airlines fly direct from Southwest Florida Intl. Airport (RSW) to Sioux Falls Regional Airport (FSD)?
You can't catch a nonstop flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to Sioux Falls Regional Airport (FSD). However, you can seamlessly travel to Sioux Falls without any layovers by taking off from Charlotte County Airport (PGD).
What is the cheapest airline that flies from Southwest Florida Intl. Airport (RSW) to Sioux Falls Regional Airport (FSD)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest RSW to FSD flight.
How many flights per day from Southwest Florida Intl. Airport (RSW) to Sioux Falls Regional Airport (FSD)?
There are no daily direct flights departing from Southwest Florida Intl. Airport (RSW) to Sioux Falls Regional Airport (FSD). But you can choose flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be on your way before you know it.
What day of the week has the most flights from RSW to FSD?
Typically you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* But this can vary based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Southwest Florida Intl. Airport (RSW) to Sioux Falls Regional Airport (FSD)?
To arrive at Sioux Falls Regional Airport (FSD) without delays, pick a flight that leaves from Southwest Florida Intl. Airport (RSW) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Southwest Florida Intl. Airport (RSW) to Sioux Falls Regional Airport (FSD) last-minute?
Booking your flight from RSW to FSD just before your getaway is usually more expensive. However, if there's some wiggle room with your departure dates and times, you could land a cheap last-minute fare.
Is it cheaper to book a RSW to FSD flight and hotel package?
Booking a RSW to FSD flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Pick from our extensive range of hotels and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Southwest Florida Intl. Airport (RSW) to Sioux Falls Regional Airport (FSD)?
If you reserved your RSW to FSD flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

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*Available to One Key members.