$234 Cheap Flights from Santa Fe (SAF) to Sioux Falls (FSD)

View $234 flight on Thu, Dec 18, 2025Opens in a new window

Popular airlines from Santa Fe Municipal Airport (SAF) to Sioux Falls Regional Airport (FSD)

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Cheap Flights from Santa Fe to Sioux Falls (SAF-FSD)

Prices were available within the past 7 days and start at $234 for one-way flights and $370 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Dec 16 - Mon, Jan 5
SAF
Santa Fe
FSD
Sioux Falls
$370 Roundtrip, found 1 day ago
$370
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Dec 16 from Santa Fe to Sioux Falls, returning Mon, Jan 5, priced at $370 found 1 day ago
American Airlines
Fri, Dec 19 - Mon, Jan 5
SAF
Santa Fe
FSD
Sioux Falls
$425 Roundtrip, found 1 day ago
$425
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Dec 19 from Santa Fe to Sioux Falls, returning Mon, Jan 5, priced at $425 found 1 day ago
United
Tue, Dec 16 - Tue, Dec 30
SAF
Santa Fe
FSD
Sioux Falls
$428 Roundtrip, found 1 day ago
$428
Roundtrip
found 1 day ago
Select United flight, departing Tue, Dec 16 from Santa Fe to Sioux Falls, returning Tue, Dec 30, priced at $428 found 1 day ago
American Airlines
Tue, Dec 16 - Sat, Jan 3
SAF
Santa Fe
FSD
Sioux Falls
$443 Roundtrip, found 1 day ago
$443
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Dec 16 from Santa Fe to Sioux Falls, returning Sat, Jan 3, priced at $443 found 1 day ago
United
Tue, Dec 16 - Fri, Jan 2
SAF
Santa Fe
FSD
Sioux Falls
$459 Roundtrip, found 1 day ago
$459
Roundtrip
found 1 day ago
Select United flight, departing Tue, Dec 16 from Santa Fe to Sioux Falls, returning Fri, Jan 2, priced at $459 found 1 day ago
American Airlines
Thu, Dec 18 - Fri, Jan 2
SAF
Santa Fe
FSD
Sioux Falls
$464 Roundtrip, found 1 day ago
$464
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Dec 18 from Santa Fe to Sioux Falls, returning Fri, Jan 2, priced at $464 found 1 day ago
United
Tue, Dec 16 - Wed, Dec 31
SAF
Santa Fe
FSD
Sioux Falls
$469 Roundtrip, found 1 day ago
$469
Roundtrip
found 1 day ago
Select United flight, departing Tue, Dec 16 from Santa Fe to Sioux Falls, returning Wed, Dec 31, priced at $469 found 1 day ago
United
Tue, Dec 16 - Sun, Jan 4
SAF
Santa Fe
FSD
Sioux Falls
$474 Roundtrip, found 1 day ago
$474
Roundtrip
found 1 day ago
Select United flight, departing Tue, Dec 16 from Santa Fe to Sioux Falls, returning Sun, Jan 4, priced at $474 found 1 day ago
American Airlines
Sun, Dec 21 - Mon, Jan 5
SAF
Santa Fe
FSD
Sioux Falls
$490 Roundtrip, found 1 day ago
$490
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Dec 21 from Santa Fe to Sioux Falls, returning Mon, Jan 5, priced at $490 found 1 day ago
American Airlines
Thu, Dec 18 - Fri, Jan 2
SAF
Santa Fe
FSD
Sioux Falls
$492 Roundtrip, found 1 day ago
$492
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Dec 18 from Santa Fe to Sioux Falls, returning Fri, Jan 2, priced at $492 found 1 day ago

Frequently asked questions

How much does a flight from Santa Fe Municipal Airport (SAF) to Sioux Falls Regional Airport (FSD) cost?
Get a cheap one-way flight from $234 or cheap return flight from $370 from Santa Fe Municipal Airport (SAF) to Sioux Falls Regional Airport (FSD) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Santa Fe Municipal Airport (SAF) to Sioux Falls Regional Airport (FSD)?
Planning your getaway for December can help you save, as it's the cheapest month for flights between SAF and FSD. You'll often find the lowest prices during off-peak months.
What is the cheapest airline that flies from Santa Fe Municipal Airport (SAF) to Sioux Falls Regional Airport (FSD)?
To find the cheapest airline that'll fly you from SAF to FSD, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Santa Fe Municipal Airport (SAF) to Sioux Falls Regional Airport (FSD)?
You'll have to take a flight with a layover if you're traveling from Santa Fe Municipal Airport (SAF) to Sioux Falls Regional Airport (FSD). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from SAF to FSD?
Generally you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Santa Fe Municipal Airport (SAF) to Sioux Falls Regional Airport (FSD)?
To touch down at Sioux Falls Regional Airport (FSD) without delays, book a flight that leaves Santa Fe Municipal Airport (SAF) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Santa Fe Municipal Airport (SAF) to Sioux Falls Regional Airport (FSD) last-minute?
Booking your plane ticket from SAF to FSD just before your journey is typically more expensive. However, if there's some wiggle room with your travel dates and times, you could score a cheap last-minute fare.
Is it cheaper to book a SAF to FSD flight and hotel package?
You'll typically save money by booking a SAF to FSD flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After selecting your ideal flights and accommodations, consider other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Santa Fe Municipal Airport (SAF) to Sioux Falls Regional Airport (FSD)?
If you booked your SAF to FSD flight within the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

Travel information

Origin airport
Santa Fe Municipal
Destination airport
Sioux Falls Regional
Airlines serving
American Airlines, United
Roundtrip price
$369
Distance
741 mi

Book with confidence

Santa Fe to Sioux Falls Flights

The cheapest times to fly from Santa Fe to Sioux Falls

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santa Fe to Sioux Falls are during the month of December. You can find some of the cheapest flights from Santa Fe to Sioux Falls with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santa Fe to Sioux Falls

Sunday is one of the best days to book for cheap flights from Santa Fe to Sioux Falls: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santa Fe to Sioux Falls

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santa Fe to Sioux Falls in 2025. You can also book with separate airlines for your outbound and return journeys, from $234 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santa Fe to Sioux Falls flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santa Fe to Sioux Falls airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santa Fe to Sioux Falls Flights

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*Available to One Key members.