$148 Cheap Flights from Santiago (SCL) to Cusco (CUZ)

Santiago (SCL) to Cusco (CUZ) at a glance

Experience a range of airlines operating flights from Santiago (SCL) to Cusco (CUZ) on this international short-haul route. Evaluate options from full-service carriers to discover an itinerary that aligns with your budget, schedule, and travel plans while you immerse yourself in the iconic sights and neighborhoods of Cusco. Here, you'll find essential information for flights departing from Arturo Merino Benitez Airport (SCL) to Alejandro Velasco Astete International Airport (CUZ).

• Fastest flight duration: around 3h 30m non-stop
• Route distance: roughly 1,400 miles (2,250 km)
• Flights per week: around 7 departures on average
• Typical fares (one-way): economy tickets often range from $130–$395, depending on seasonality and how far ahead you book

Flights from Arturo Merino Benitez Airport (SCL) to Alejandro Velasco Astete International Airport (CUZ)

According to recent travel bookings, the most popular airlines for trips from Santiago to Cusco offer both non-stop and one-stop flights, frequently featuring a layover at Jorge Chávez International Airport (LIM) with an average duration of about 2 hours and 15 minutes. This allows travelers the flexibility to compare prices, total travel times, and cabin classes to secure the best possible itinerary.

• LATAM Airlines Group: This comprehensive airline provides both non-stop and one-stop flights, commanding around 95% of the departures on this route. One-way ticket prices usually fall between $135 and $410, with a direct flight taking approximately 3 hours and 30 minutes.
• Sky Airlines: A full-service airline that offers one-stop options, Sky Airlines represents about 5% of the flights on this route. One-way fares are generally priced between $130 and $250, with a flight duration of 5 hours and 15 minutes and a total travel time around 7 hours and 30 minutes, including layover time.

Travelers can enhance their journey from Santiago to Cusco with an upgrade to premium economy service available through LATAM Airlines Group on this route.

How to find the best prices for flights from Santiago (SCL) to Cusco (CUZ)

Getting some of the best deals on flights from Santiago to Cusco is all about timing and flexibility. Here are some key tips to help you save:

1. Best times to book and fly: cheaper fares are often found when booking at least two months in advance, which coincides with when most travelers make their reservations. Evening departures (6 PM to 12 AM) typically offer lower prices, while afternoon flights (12 PM to 6 PM) are more popular. Additionally, flying on Sunday generally yields cheaper rates, even though Monday is the busiest travel day.
2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Cusco hotel and flight deals.
4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Alejandro Velasco Astete International Airport from Arturo Merino Benitez Airport

Cusco welcomes travelers from Santiago with a range of transport options based on price, convenience, and proximity. Here's how to reach Cusco efficiently:

• Hotel transfer: Transfers offer a convenient way to reach your hotel in Cusco, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
• Car rental: Renting a car from Alejandro Velasco Astete International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Alejandro Velasco Astete International Airport on Expedia.
• Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
• Public transportation: From Alejandro Velasco Astete International Airport, several transport options are conveniently accessible by car: Cusco Bus Station, located about 1.6 miles from the airport, is the nearest option, followed by Cusco Wanchaq Station, a train station about 2.5 miles away, and Cusco Seaport, a seaport situated approximately 3.2 miles from the airport.

Santiago to Cusco Flights

The cheapest times to fly from Santiago to Cusco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Cusco are during the month of March. You can find some of the cheapest flights from Santiago to Cusco with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Santiago to Cusco

Sunday is one of the best days to book for cheap flights from Santiago to Cusco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Santiago to Cusco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Cusco in 2026. You can also book with separate airlines for your outbound and return journeys, from $148 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Cusco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Cusco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.