$549 Cheap Flights from Santa Cruz (VVI) to Bilbao (BIO)

View $549 flight on Tue, Nov 18, 2025Opens in a new window

Popular airlines from Santa Cruz (VVI-Viru Viru Intl.) to Bilbao Airport (BIO)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Santa Cruz to Bilbao (VVI-BIO)

Prices were available within the past 7 days and start at $549 for one-way flights and $1,074 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Sat, Dec 6 - Sun, Jan 18
VVI
Santa Cruz
BIO
Bilbao
$1,074 Roundtrip, found 5 days ago
$1,074
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Sat, Dec 6 from Santa Cruz to Bilbao, returning Sun, Jan 18, priced at $1,074 found 5 days ago
Boliviana De Aviacion
Sat, Dec 6 - Sun, Jan 18
VVI
Santa Cruz
BIO
Bilbao
$1,087 Roundtrip, found 5 days ago
$1,087
Roundtrip
found 5 days ago
Select Boliviana De Aviacion flight, departing Sat, Dec 6 from Santa Cruz to Bilbao, returning Sun, Jan 18, priced at $1,087 found 5 days ago
Boliviana De Aviacion
Sat, Dec 6 - Sun, Jan 18
VVI
Santa Cruz
BIO
Bilbao
$1,096 Roundtrip, found 5 days ago
$1,096
Roundtrip
found 5 days ago
Select Boliviana De Aviacion flight, departing Sat, Dec 6 from Santa Cruz to Bilbao, returning Sun, Jan 18, priced at $1,096 found 5 days ago
Air Europa
Sat, Dec 6 - Sun, Jan 18
VVI
Santa Cruz
BIO
Bilbao
$1,130 Roundtrip, found 5 days ago
$1,130
Roundtrip
found 5 days ago
Select Air Europa flight, departing Sat, Dec 6 from Santa Cruz to Bilbao, returning Sun, Jan 18, priced at $1,130 found 5 days ago
Air Europa
Sat, Dec 6 - Sun, Jan 18
VVI
Santa Cruz
BIO
Bilbao
$1,139 Roundtrip, found 5 days ago
$1,139
Roundtrip
found 5 days ago
Select Air Europa flight, departing Sat, Dec 6 from Santa Cruz to Bilbao, returning Sun, Jan 18, priced at $1,139 found 5 days ago
Air Europa
Sat, Dec 6 - Sun, Jan 18
VVI
Santa Cruz
BIO
Bilbao
$1,194 Roundtrip, found 5 days ago
$1,194
Roundtrip
found 5 days ago
Select Air Europa flight, departing Sat, Dec 6 from Santa Cruz to Bilbao, returning Sun, Jan 18, priced at $1,194 found 5 days ago
LATAM Airlines Group
Sat, Dec 6 - Sun, Jan 18
VVI
Santa Cruz
BIO
Bilbao
$1,195 Roundtrip, found 5 days ago
$1,195
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Sat, Dec 6 from Santa Cruz to Bilbao, returning Sun, Jan 18, priced at $1,195 found 5 days ago
Air Europa
Sat, Dec 6 - Sun, Jan 18
VVI
Santa Cruz
BIO
Bilbao
$1,202 Roundtrip, found 5 days ago
$1,202
Roundtrip
found 5 days ago
Select Air Europa flight, departing Sat, Dec 6 from Santa Cruz to Bilbao, returning Sun, Jan 18, priced at $1,202 found 5 days ago
Boliviana De Aviacion
Sat, Dec 6 - Sun, Jan 18
VVI
Santa Cruz
BIO
Bilbao
$1,261 Roundtrip, found 5 days ago
$1,261
Roundtrip
found 5 days ago
Select Boliviana De Aviacion flight, departing Sat, Dec 6 from Santa Cruz to Bilbao, returning Sun, Jan 18, priced at $1,261 found 5 days ago
avianca
Fri, Jan 30 - Tue, Feb 10
VVI
Santa Cruz
BIO
Bilbao
$1,438 Roundtrip, found 3 days ago
$1,438
Roundtrip
found 3 days ago
Select avianca flight, departing Fri, Jan 30 from Santa Cruz to Bilbao, returning Tue, Feb 10, priced at $1,438 found 3 days ago

Frequently asked questions

How much does a flight from Viru Viru Intl. Airport (VVI) to Bilbao Airport (BIO) cost?
Lock in a cheap one-way flight from $549 or cheap return flight from $1,074 from Viru Viru Intl. Airport (VVI) to Bilbao Airport (BIO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Viru Viru Intl. Airport (VVI) to Bilbao Airport (BIO)?
The cheapest month to fly from VVI to BIO is December, when there's less demand. Off-peak season is often when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Viru Viru Intl. Airport (VVI) to Bilbao Airport (BIO)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find the carrier with the cheapest VVI to BIO flight.
How many flights per day from Viru Viru Intl. Airport (VVI) to Bilbao Airport (BIO)?
Nonstop flights from Viru Viru Intl. Airport (VVI) to Bilbao Airport (BIO) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from VVI to BIO?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Viru Viru Intl. Airport (VVI) to Bilbao Airport (BIO)?
To avoid possible delays on the Viru Viru Intl. Airport (VVI) to Bilbao Airport (BIO) route, aim to travel before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Viru Viru Intl. Airport (VVI) to Bilbao Airport (BIO) last-minute?
Holding off until right before your break to book a ticket from VVI to BIO often results in higher prices. While it's possible to find some last-minute deals, they aren't always guaranteed. Keep your travel plans flexible for the best chance of landing a bargain.
Is it cheaper to book a VVI to BIO flight and hotel package?
Opting for a VVI to BIO flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Pick from our extensive range of hotels and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Viru Viru Intl. Airport (VVI) to Bilbao Airport (BIO)?
It's usually possible to cancel or reschedule your VVI to BIO flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Viru Viru Intl.
Destination airport
Bilbao
Roundtrip price
$1,074
Distance
5676 mi

Book with confidence

Santa Cruz to Bilbao Flights

The cheapest times to fly from Santa Cruz to Bilbao

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santa Cruz to Bilbao are during the month of December. You can find some of the cheapest flights from Santa Cruz to Bilbao with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santa Cruz to Bilbao

Sunday is one of the best days to book for cheap flights from Santa Cruz to Bilbao: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santa Cruz to Bilbao

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santa Cruz to Bilbao in 2025. You can also book with separate airlines for your outbound and return journeys, from $549 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santa Cruz to Bilbao flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santa Cruz to Bilbao airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santa Cruz to Bilbao Flights

Explore a world of travel with Expedia

*Available to One Key members.