Title: Isla del Rey Adventure Vacations 2026 | Expedia.com ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Isla del Rey Adventure Vacations ## Book a Adventure Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Top Adventure vacation packages in Isla del Rey Price found within the past 48 hours. Click for updated prices. ![Yoo by Wynwood House](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/f526e4da_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Yoo by Wynwood House Calidonia $827 per person Apr 19 - Apr 24 found 14 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9.2/10 Wonderful! (5 reviews) Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone. Reviewed on Jul 26, 2025 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo Save 100% on your flight $1,029 per person Apr 19 - Apr 24 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) The room had no window to the outside it instead had a large window into an interior hall. Maid service was inconsistent. Breakfast was not a good value. Reviewed on Feb 5, 2026 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco Save 100% on your flight $882 per person Apr 28 - May 3 found 1 day ago Roundtrip non-stop flight included New York (JFK) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) Nice hotel. Friendly staff Reviewed on Feb 9, 2026 ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Dreams Playa Bonita Panama - All Inclusive Save 100% on your flight $1,803 per person Mar 23 - Mar 29 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 7.4/10 Good! (1,002 reviews) It was a wonderful stay with wonderful people Reviewed on Feb 7, 2026 ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista $852 per person Apr 6 - Apr 11 found 2 days ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) Room was spotless. Staff very courteous. Reviewed on Feb 10, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla del Rey [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-10/2026-03-17/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Adventure vacations in Isla del Rey Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista $852 per person Apr 6 - Apr 11 found 2 days ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) Room was spotless. Staff very courteous. Reviewed on Feb 10, 2026 ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### JW Marriott Panama San Francisco $1,020 per person Apr 6 - Apr 11 found 2 days ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,003 reviews) Beautiful hotel, great service. Breakfast buffet is amazing. Reviewed on Jan 29, 2026 ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### W Panama Bella Vista $1,014 per person Apr 6 - Apr 11 found 2 days ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,001 reviews) The room was very clean, the staff and amenities were excellent. My only complaint is the thin walls and windows. I heard everything going on in the next room, and all the cars blowing their horns outside. I was on the 17th floor and it was like I was outside. Reviewed on Feb 8, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla del Rey [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-10/2026-03-17/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Adventure vacations in Isla del Rey Price found within the past 48 hours. Click for updated prices. ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco $713 per person Apr 27 - Apr 30 found 19 hours ago Roundtrip flight included Port of Spain (POS) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) Nice hotel. Friendly staff Reviewed on Feb 9, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo $880 per person Apr 5 - Apr 8 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) The room had no window to the outside it instead had a large window into an interior hall. Maid service was inconsistent. Breakfast was not a good value. Reviewed on Feb 5, 2026 ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Dreams Playa Bonita Panama - All Inclusive $1,043 per person Apr 5 - Apr 8 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 7.4/10 Good! (1,002 reviews) It was a wonderful stay with wonderful people Reviewed on Feb 7, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla del Rey [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-10/2026-03-17/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 4 Night Adventure vacations in Isla del Rey Price found within the past 48 hours. Click for updated prices. ![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mahogany Suites $614 per person Apr 22 - Apr 26 found 14 hours ago Roundtrip flight included New York (JFK) to Panama City (PTY) 10/10 Exceptional! (1 review) Excellent apartment on a golf resort. 5 Star. Reviewed on Jan 28, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo $1,059 per person Mar 16 - Mar 20 found 20 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) The room had no window to the outside it instead had a large window into an interior hall. Maid service was inconsistent. Breakfast was not a good value. Reviewed on Feb 5, 2026 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco $994 per person Mar 19 - Mar 23 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) Nice hotel. Friendly staff Reviewed on Feb 9, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla del Rey [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-10/2026-03-17/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Find awesome Isla del Rey adventure vacations #### How can I book the best Isla del Rey adventure trips? Choose your own adventure in Isla del Rey, whether that’s a white-knuckle experience or a weekend walk. Read the reviews of the adventures that have gone before to be sure your chosen stay is your idea of fun. #### How can I plan the perfect Isla del Rey family adventure vacation? Adventure awaits when you select the family-friendly filter. There’s plenty of excitement for all ages in Isla del Rey. Just make sure to check your chosen escapade is within the realms of can-do for the whole clan and will have the whole team grinning. #### Can I book all-inclusive Isla del Rey adventure vacation packages? By refining your filters, you can explore all-amazing, all-adventurous, all-inclusive vacation packages. Amp up the extravagance with a few more filters too. Pick pristine pools, sensational spas, or wondrous waterparks for a sensational adventure getaway. #### Why should I book a Isla del Rey adventure vacation for couples? Book a Isla del Rey couples adventure vacation for the ultimate in romance and memory-making. Stunning scenery, heart-racing happenings, and the grandeur of the great outdoors—it’s the best way to bond. #### How can I find the best deals on adventure packages in Isla del Rey? It’s easy to unleash fabulously affordable adventures. Enter the dates for your caper, then sort your search results by price or deals. #### Can I book an adventure vacation package in Isla del Rey with free cancellation and/or flexible dates? Yes! When you’re searching for a great getaway, filter by payment option for free cancellation, so a change of plans won’t mess up your adventures. You’ll find buy now, pay later options, too, for full-on flexibility. #### Why should I book a Isla del Rey adventure trip with Expedia? Adventure, airfare, accommodation, ATOL protection, and activities—all on one site. And that’s just the benefits that begin with A. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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](https://expedia.com/Cheap-Flights-To-Isla-Del-Rey.d6336628.Travel-Guide-Flights)[ Isla del Rey Hotels ](https://expedia.com/Isla-Del-Rey-Hotels.d6336628.Travel-Guide-Hotels)[ Vacation Rentals in Isla del Rey ](https://expedia.com/Isla-Del-Rey-Vacation-Rentals.d6336628.Travel-Guide-VacationRentals)[ Car Rentals in Isla del Rey ](https://expedia.com/Car-Rentals-In-Isla-Del-Rey.d6336628.Car-Rental-Guide)[ Isla del Rey Vacations ](https://expedia.com/Isla-Del-Rey.d6336628.Destination-Travel-Guides) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app