Title: The Best 4 Star Hotels in Fredericktown, MO  | Expedia.com

[Fredericktown Travel Guide](https://expedia.com/Fredericktown.dx55114)[Hotels in Fredericktown](https://expedia.com/Fredericktown-Hotels.d55114.Travel-Guide-Hotels)[Vacation Rentals in Fredericktown](https://expedia.com/Fredericktown-Vacation-Rentals.d55114.Travel-Guide-VacationRentals)[Flights to Fredericktown](https://expedia.com/Cheap-Flights-To-Fredericktown.d55114.Travel-Guide-Flights)[Car Rentals in Fredericktown](https://expedia.com/Car-Rentals-In-Fredericktown.d55114.Car-Rental-Guide)[Fredericktown Vacation Packages](https://expedia.com/Fredericktown.d55114.Destination-Travel-Guides)

![Castor River Shut-Ins Fredericktown Missouri Ozarks](https://images.trvl-media.com/place/55114/f689985b-15df-4aa2-b301-649b2fafd71b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Fredericktown 4 Star Hotels

Tonight

[Feb 11 - Feb 12](https://www.expedia.com/Hotel-Search?regionId=55114&startDate=2026-02-11&endDate=2026-02-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 12 - Feb 13](https://www.expedia.com/Hotel-Search?regionId=55114&startDate=2026-02-12&endDate=2026-02-13&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=55114&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=55114&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Fredericktown 4-star hotels

![Street view](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/1b66adae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/198bc377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, streaming services](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/eeb333c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![City view from property](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/4840d660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Urban Lofts

[](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h39926011.Hotel-Information)

Perryville

[](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h39926011.Hotel-Information)

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## Learn more about Fredericktown

Stroll through the historic courthouse square where local shops serve homemade treats and the 1822 courthouse stands proudly. Outdoor enthusiasts can paddle the St. Francis River or hike nearby Mark Twain National Forest trails when summer temperatures cool in the evening.

[See all hotels in Fredericktown](https://www.expedia.com/Hotel-Search?startDate=2026-02-26&endDate=2026-02-27&adults=2&regionId=55114)

![Castor River Shut-Ins Fredericktown Missouri Ozarks](https://images.trvl-media.com/place/55114/f689985b-15df-4aa2-b301-649b2fafd71b.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high)

## Top Fredericktown Hotel Reviews

## Find out more about Fredericktown

## Fredericktown Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Fredericktown, Missouri are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Fredericktown 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Fredericktown. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Fredericktown, Missouri, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Fredericktown hotels offer everything your heart desires.

## Frequently asked questions

### How much does it cost to stay in a 4-star hotel in Fredericktown?

> - Search for the lowest price

### What's the difference between 5-star and 4-star hotels in Fredericktown?

### Does Fredericktown have any 4-star all-inclusive resorts?

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