Title: The Best 4 Star Hotels in Mayagüez from $171 | Expedia.com [Mayagüez Travel Guide](https://expedia.com/Mayaguez.dx2215)[Hotels in Mayagüez](https://expedia.com/Mayaguez-Hotels.d2215.Travel-Guide-Hotels)[Vacation Rentals in Mayagüez](https://expedia.com/Mayaguez-Vacation-Rentals.d2215.Travel-Guide-VacationRentals)[Flights to Mayagüez](https://expedia.com/Cheap-Flights-To-Mayaguez.d2215.Travel-Guide-Flights)[Things to do in Mayagüez](https://expedia.com/Things-To-Do-In-Mayaguez.d2215.Travel-Guide-Activities)[Car Rentals in Mayagüez](https://expedia.com/Car-Rentals-In-Mayaguez.d2215.Car-Rental-Guide)[Mayagüez Vacation Packages](https://expedia.com/Mayaguez.d2215.Destination-Travel-Guides) ![Christopher Columbus Statue showing a statue or sculpture and a fountain](https://images.trvl-media.com/place/553248621532872895/1e4308eb-a0ff-4373-a28d-418bbb76380e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248621532872895/1e4308eb-a0ff-4373-a28d-418bbb76380e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mayagüez 4 Star Hotels Tonight [Feb 26 - Feb 27](https://www.expedia.com/Hotel-Search?regionId=2215&startDate=2026-02-26&endDate=2026-02-27&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 27 - Feb 28](https://www.expedia.com/Hotel-Search?regionId=2215&startDate=2026-02-27&endDate=2026-02-28&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=2215&startDate=2026-02-27&endDate=2026-03-01&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=2215&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mayagüez 4-star hotels ![Beach nearby, white sand, beach towels](https://images.trvl-media.com/lodging/12000000/11930000/11928100/11928077/da6c7968.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11930000/11928100/11928077/eb49b31f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11930000/11928100/11928077/59d48b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Ocean View | Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/12000000/11930000/11928100/11928077/2196f975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Parguera Plaza Hotel - Adults Only [](https://www.expedia.com/Lajas-Hotels-Parguera-Plaza-Hotel.h11928077.Hotel-Information) Lajas 9.6/10 Exceptional (720 reviews) "Amazing staff and room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) selita $157 nightly $171 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Lajas-Hotels-Parguera-Plaza-Hotel.h11928077.Hotel-Information) ![Luxury Room | Frette Italian sheets, hypo-allergenic bedding, down comforters](https://images.trvl-media.com/lodging/6000000/5560000/5558100/5558043/f7ff1c34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Room | Frette Italian sheets, hypo-allergenic bedding, down comforters](https://images.trvl-media.com/lodging/6000000/5560000/5558100/5558043/065d3bf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/6000000/5560000/5558100/5558043/317b8653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Room | Frette Italian sheets, hypo-allergenic bedding, down comforters](https://images.trvl-media.com/lodging/6000000/5560000/5558100/5558043/1a5406b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Isabela [](https://www.expedia.com/Isabela-Hotels-Royal-Isabela.h5558043.Hotel-Information) Isabela 9.6/10 Exceptional (164 reviews) "Staff, restaurant, the view" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vanessa $755 nightly $823 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Isabela-Hotels-Royal-Isabela.h5558043.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/94000000/93260000/93252500/93252477/07ccb9a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/94000000/93260000/93252500/93252477/c91ac589.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 1 Bedroom, Ocean View | Private kitchen | Full-size fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/94000000/93260000/93252500/93252477/254a3d2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/94000000/93260000/93252500/93252477/0223186e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aguada Beach Condos [](https://www.expedia.com/Aguada-Hotels-Aguada-Beach-Condos.h93252477.Hotel-Information) Aguada 9.6/10 Exceptional (44 reviews) "Everything was perfect space and cleanliness and view places to eat nearby " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis [](https://www.expedia.com/Aguada-Hotels-Aguada-Beach-Condos.h93252477.Hotel-Information) ![Honeymoon Cottage, 1 Double Bed, Balcony, Mountain View | Premium bedding, down comforters, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/10000000/9740000/9734300/9734272/67431e1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Cottage, 1 Double Bed, Balcony, Mountain View | Bathroom | Jetted tub, designer toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/10000000/9740000/9734300/9734272/8e95e2ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/10000000/9740000/9734300/9734272/0be9357e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/10000000/9740000/9734300/9734272/c11014a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hacienda El Jibarito [](https://www.expedia.com/San-Sebastian-Hotels-Hacienda-El-Jibarito.h9734272.Hotel-Information) San Sebastian 8.4/10 Very Good (174 reviews) "I've stayed here before and it's always been perfect; this time was just as perfect. The staff and management are excellent, ensuring a beautiful and enjoyable stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Candido [](https://www.expedia.com/San-Sebastian-Hotels-Hacienda-El-Jibarito.h9734272.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mayaguez-Hotels.s40-0-d2215.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Mayaguez-Hotels.s40-0-d2215.Travel-Guide-Filter-Hotels) ## Learn more about Mayagüez Stroll through Plaza Colon, where Christopher Columbus' statue stands sentinel over the city's historic heart. Explore the lush grounds of the Tropical Agriculture Research Station or venture to nearby Mona Island for pristine beaches and hiking trails. [See all hotels in Mayagüez](https://www.expedia.com/Hotel-Search?startDate=2026-03-12&endDate=2026-03-13&adults=2®ionId=2215) ![Christopher Columbus Statue showing a statue or sculpture and a fountain](https://images.trvl-media.com/place/553248621532872895/1e4308eb-a0ff-4373-a28d-418bbb76380e.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Mayagüez Hotel Reviews ![Parguera Plaza Hotel - Adults Only](https://images.trvl-media.com/lodging/12000000/11930000/11928100/11928077/bc417397_y.jpg) ### Parguera Plaza Hotel - Adults Only 10/10 Excellent "We always have a wonderful stay here. The staff members are very nice and attentive and everything is clean and taken care of! " [](https://expedia.com/Lajas-Hotels-Parguera-Plaza-Hotel.h11928077.Hotel-Information) ## Find out more about Mayagüez ## Mayagüez Four Star Hotel Information When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Mayagüez, Puerto Rico are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Mayagüez 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service. Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Mayagüez. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Mayagüez, Puerto Rico, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop. Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Mayagüez hotels offer everything your heart desires. ## Frequently asked questions ### How much does it cost to stay in a 4-star hotel in Mayagüez? > - Search for the lowest price from $171 ### What's the difference between 5-star and 4-star hotels in Mayagüez? ### Does Mayagüez have any 4-star all-inclusive resorts? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Plaza Colon ](https://www.expedia.com/Plaza-Colon-Hotels.0-l6081861-0.Travel-Guide-Filter-Hotels) - [Hotels near Christopher Columbus Statue ](https://www.expedia.com/Christopher-Columbus-Statue-Hotels.0-l553248621532872895-0.Travel-Guide-Filter-Hotels) - [Hotels near Catedral de Nuestra Senora de la Candelaria ](https://www.expedia.com/Catedral-De-Nuestra-Senora-De-La-Candelaria-Hotels.0-l553248621533157904-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Santurce ](https://www.expedia.com/3Star-Santurce-Hotels.s30-0-d500172.Travel-Guide-Filter-Hotels) - 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