Find 4 Star Hotels in Mebane, NC from $107

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Check availability on Mebane 4 Star Hotels

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Our top choices for Mebane 4-star hotels

Terrace/patio
JB Duke Hotel

JB Duke Hotel

JB Duke Hotel
4.0 star property
Durham
9.4 out of 10, Exceptional, (552)
"Excellent on all levels! Will definitely stay here again!"
United States
Cherie Nan
$149 nightly
The price is $169
Jan 5 - Jan 6
Total with taxes and fees
JB Duke Hotel
Interior entrance
21c Museum Hotel Durham

21c Museum Hotel Durham

21c Museum Hotel Durham
4.0 star property
Downtown Durham
8.4 out of 10, Very Good, (1004)
"Amazing staff, comfortable rooms, best shower, convenient location. "
United States
Lauren
$165 nightly
The price is $187
Jan 25 - Jan 26
Total with taxes and fees
21c Museum Hotel Durham
Exterior
DoubleTree Suites by Hilton Raleigh - Durham

DoubleTree Suites by Hilton Raleigh - Durham

DoubleTree Suites by Hilton Raleigh - Durham
4.0 star property
Durham
9.0 out of 10, Wonderful, (1008)
"Spacious and clean room, friendly staff, great experience!"
United States
Jing
$94 nightly
The price is $107
Jan 11 - Jan 12
Total with taxes and fees
DoubleTree Suites by Hilton Raleigh - Durham
Indoor pool
Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club
4.0 star property
Durham
9.4 out of 10, Exceptional, (1003)
"Family friendly! "
United States
Tanisha
$142 nightly
The price is $162
Jan 18 - Jan 19
Total with taxes and fees
Washington Duke Inn & Golf Club
Premium bedding, desk, blackout drapes, iron/ironing board
The Durham Hotel

The Durham Hotel

The Durham Hotel
4.0 star property
Downtown Durham
9.0 out of 10, Wonderful, (647)
"Great stay. Very nice boutique hotel. "
United States
nadav
$186 nightly
The price is $211
Jan 8 - Jan 9
Total with taxes and fees
The Durham Hotel
Lobby
The Carolina Inn, a Destination by Hyatt Hotel

The Carolina Inn, a Destination by Hyatt Hotel

The Carolina Inn, a Destination by Hyatt Hotel
4.5 star property
Chapel Hill
9.6 out of 10, Exceptional, (1002)
"nice location"
United States
aakash
$271 nightly
The price is $308
Jan 5 - Jan 6
Total with taxes and fees
The Carolina Inn, a Destination by Hyatt Hotel
Dinner served, American cuisine
Graduate by Hilton Chapel Hill

Graduate by Hilton Chapel Hill

Graduate by Hilton Chapel Hill
4.0 star property
Chapel Hill
9.2 out of 10, Wonderful, (1003)
"This hotel was such a nice surprise! The indoor basketball court for the kids, the amazing bar, and the friendly staff were top notch. Will definitely stay here again!"
United States
Robyn
$147 nightly
The price is $167
Jan 12 - Jan 13
Total with taxes and fees
Graduate by Hilton Chapel Hill
Property grounds
Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel
4.0 star property
Chapel Hill
9.6 out of 10, Exceptional, (1002)
"Nice quiet plave without a lot of character. "
United States
Catherine
$178 nightly
The price is $202
Jan 14 - Jan 15
Total with taxes and fees
Rizzo Center, a Destination by Hyatt Hotel
Property amenity
Landing Apartments Durham

Landing Apartments Durham

Landing Apartments Durham
4.0 star property
Downtown Durham
8.8 out of 10, Excellent, (23)
"Awesome experience! The apartment was very clean and surprisingly located to all almost every thing we had planned! Great spot for our 25th Anniversary!!'"
United States
Les
Landing Apartments Durham
Garden
Arrowhead Inn

Arrowhead Inn

Arrowhead Inn
4.5 star property
Durham
9.8 out of 10, Exceptional, (121)
"Wonderful place to stay!"
United States
Ozcan
$207 nightly
The price is $235
Jan 5 - Jan 6
Total with taxes and fees
Arrowhead Inn
Terrace/patio
The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel
4.0 star property
Hillsborough
9.6 out of 10, Exceptional, (266)
"The room was great. Very clean. The staff was absolutely amazing! 10 out of 10! "
United States
Stuart
$134 nightly
The price is $152
Jan 25 - Jan 26
Total with taxes and fees
The Colonial Inn, an Ascend Collection Hotel
Exterior
The Siena Hotel, Autograph Collection

The Siena Hotel, Autograph Collection

The Siena Hotel, Autograph Collection
4.0 star property
Chapel Hill
9.4 out of 10, Exceptional, (919)
"Great stay. Would absolutely stay again. "
United States
Anthony
The Siena Hotel, Autograph Collection
Outdoor spa tub
Chapel Hill/Durham Retreat w/ Hot tub, full body massage chair, fenced dog area.

Chapel Hill/Durham Retreat w/ Hot tub, full body massage chair, fenced dog area.

Chapel Hill/Durham Retreat w/ Hot tub, full body massage chair, fenced dog area.
4.0 star property
Chapel Hill
9.8 out of 10, Exceptional, (13)
"Nice home with great amenities and close to everything "
United States
Kristi H.
Chapel Hill/Durham Retreat w/ Hot tub, full body massage chair, fenced dog area.
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Learn more about Mebane

This charming small town boasts the Tanger Outlets where savvy shoppers find designer deals without the big-city crowds. Stroll through the historic downtown for local eateries, the Clay Street Mural, and weekend festivals where locals welcome visitors with genuine Southern hospitality.

See all hotels in Mebane
Farm surrounded by a harvested field

Top Mebane Hotel Reviews

The Durham Hotel

The Durham Hotel

10/10 Excellent
"We stayed here for NYE/New Year's Day, and the front desk team was incredible. They were personable, energetic, responsive, and kind. The Suite is a great choice for a stay--it's spacious and perfectly situated in the hotel. What a great place to close out 2025 and ring in 2026!"
Lauren Lee 1-night trip
Posted 2 days ago
The Durham Hotel

Find out more about Mebane

Mebane Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Mebane, North Carolina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Mebane 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Mebane. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Mebane, North Carolina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Mebane hotels offer everything your heart desires.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Mebane?
With Expedia's handy filter tool, landing an awesome deal on a 4-star hotel in Mebane just got simpler. Start by keying in your chosen travel dates and length of your escape. Then list the results by price and pick the option that best fits your style and budget.

  • Search for the lowest price from $107

What's the difference between 5-star and 4-star hotels in Mebane?
Offering an inviting traveler experience and upscale décor, 4-star hotels are an excellent option for your Mebane vacation. These types of stays generally feature lots of useful amenities that make it simple to kick back and relax — think 24-hour room service, restaurants and pools. Or get a taste of the high life at a 5-star hotel designed to spoil you with exclusive perks and amenities. Concierge assistance, premium toiletries and gourmet dining are typically included at these plush properties.
Does Mebane have any 4-star all-inclusive resorts?
Enjoy a relaxing vacation experience where almost everything is included in the one upfront rate by using our "All inclusive" filter. Keeping to your budget is a breeze when your meals, accommodations and activities are already taken care of. Eager for more options? Browse the great deals on Expedia's standard 4-star stays in and around Mebane.

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