A river winding through a dense forest.

Find 4 Star Hotels in Mesopotamia from $69

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Check availability on Mesopotamia 4 Star Hotels

Tonight
Sep 29 - Sep 30
Tomorrow
Sep 30 - Oct 1
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Mesopotamia 4-star hotels

A modern living room with a large TV, a round coffee table, and a sofa.
A swimming pool with lounge chairs and a modern building in the background.
A gym with stationary bikes and a treadmill, large windows with a city view, and a curved ceiling.
A hallway with a glass wall, potted plants, and a salon exit sign.

1. Holiday Inn Rosario by IHG

Holiday Inn Rosario by IHG
Rosario Centro
United States
Sean Anthony
$116 nightly
$116 total
Oct 18 - Oct 19
Holiday Inn Rosario by IHG
A terrace with a view of a sunset over a body of water, furnished with a sofa, chairs, and a small table.
A modern interior with a glass wine rack, a seating area with a sofa and coffee table, and a bar with stools.
A restaurant with a modern interior, featuring leather seating, a bar area with stools, and large windows offering a view of the outdoors.
A modern lobby with a curved sofa, a round coffee table, and a bookshelf filled with decorative items.

2. Marriott Corrientes Hotel

Marriott Corrientes Hotel
Corrientes
Australia
Marcus
$143 nightly
$143 total
Oct 5 - Oct 6
Marriott Corrientes Hotel
A rooftop pool with a glass balustrade, offering a view of high-rise buildings and a body of water.
A rooftop terrace with a hot tub, red lounge chairs, and potted plants.
A modern interior with a wooden dining table, black cushioned chairs, and pendant lighting.
A modern hotel lobby with a marble reception desk, leather seating, and large windows offering natural light.

3. Dazzler by Wyndham Rosario

Dazzler by Wyndham Rosario
Rosario
United States
Amadeo
$91 nightly
$91 total
Oct 3 - Oct 4
Dazzler by Wyndham Rosario
A spacious lobby with a central circular area, a staircase, and a bar area with multiple seating options.
A pool area with lounge chairs and a clear blue sky.
A bar area with a floral arrangement and a cocktail on the counter.
A multi-story hotel with a curved facade, a central entrance, and a balcony on the upper floors.

4. InterTower Hotel

InterTower Hotel
Santa Fe
Canada
Alfred Miels
$117 nightly
$117 total
Oct 4 - Oct 5
InterTower Hotel
A pool with a water feature, a modern building with large windows, and palm trees in the background.
A spacious lobby with modern furniture, a staircase, and a reception area.
A modern spa area with a hot tub, wooden flooring, and a seating area with plants.
A lobby with wooden panel walls, two elevators, a reception desk, and a seating area with wicker furniture.

5. Howard Johnson Plaza La Ribera

Howard Johnson Plaza La Ribera
Resistencia
Brazil
Augusto Miguel
$80 nightly
$80 total
Oct 1 - Oct 2
Howard Johnson Plaza La Ribera
A nighttime pool area with lounge chairs, a stone facade, and a sign for 'AMERICAN HOTEL ZURICH'.
A modern building with a curved glass facade and a classical base.
A spacious lobby with a high ceiling, marble walls, and a central column. There are seating areas with chairs and tables, and a reception desk.
A hotel lobby with a casino area featuring slot machines and a red carpet.

6. Amérian Hotel Casino Gala

Amérian Hotel Casino Gala
Resistencia
United States
Daniel
$69 nightly
$69 total
Sep 30 - Oct 1
Amérian Hotel Casino Gala
A man standing in front of a building with an ornate entrance, large windows, and a chandelier.
A bar with a long counter, shelves with framed pictures, and a large screen displaying a person.
An outdoor seating area with tables and chairs, a decorative building with a dome and green accents, and potted plants.
A grand staircase with ornate railings and a chandelier, leading to a reception area with a black and white color scheme and a marble floor.

7. Esplendor by Wyndham Savoy Rosario

Esplendor by Wyndham Savoy Rosario
Rosario Centro
United States
Susana
$94 nightly
$94 total
Oct 3 - Oct 4
Esplendor by Wyndham Savoy Rosario
A modern building with a glass facade, multiple floors, and a flat roof.
A modern kitchen with a marble countertop, stainless steel appliances, and a wooden floor.
A reception area with a wooden reception desk, seating area, and a brick wall with framed pictures.
A hotel room with a large bed, a desk with a chair, a TV, and a kitchenette.

8. Brickton, Rosario, Apartments By Marriott Bonvoy

Brickton, Rosario, Apartments By Marriott Bonvoy
Rosario Centro
United States
Sebastian
$70 nightly
$70 total
Sep 30 - Oct 1
Brickton, Rosario, Apartments By Marriott Bonvoy
A rooftop pool with wooden loungers and a city view.
A modern living room with a sectional sofa, a round coffee table, and a large abstract sculpture.
A bar area with a wooden bar counter, multiple seating options, and a large wine rack.
An outdoor seating area with white tables and chairs, surrounded by palm trees and greenery, with a modern building in the background.

9. Los Silos Hotel

Los Silos Hotel
Santa Fe
United States
Russell
$132 nightly
$132 total
Oct 18 - Oct 19
Los Silos Hotel
A modern building with a reflective glass facade, vertical lines, and potted plants.
A rooftop pool with a glass barrier, overlooking a cityscape and a body of water.
A modern hotel lobby with a sleek, metallic wall featuring circular perforations, a polished floor, and a well-lit corridor leading to elevators.
A modern building with cylindrical structures and a glass facade.

10. Puerto Norte Design Hotel

Puerto Norte Design Hotel
Rosario
United States
Rosalia
$141 nightly
$141 total
Oct 30 - Oct 31
Puerto Norte Design Hotel
A pool area with a fountain, palm trees, and a paved walkway.
A courtyard with a fountain, lounge chairs, and string lights.
A hotel lobby with a reception desk, a staircase, potted plants, and a waterfall feature.
A hotel lobby with a piano, sofas, chairs, a bar area, and a large mirror.

11. Turismo Hotel Casino

Turismo Hotel Casino
Corrientes
United States
Laura
$90 nightly
$90 total
Oct 5 - Oct 6
Turismo Hotel Casino
A modern pool area with lounge chairs and palm trees.
A multi-level atrium with glass railings, a central column, and a reception area with red chairs.
A modern interior with a bar area, seating, and large framed artworks.
A hotel room with two beds, a wooden headboard, a nightstand, a wall-mounted lamp, and a large window with a view of greenery.

12. Radisson RED Funes

Radisson RED Funes
Funes
$128 nightly
$128 total
Oct 25 - Oct 26
Radisson RED Funes
A cozy room with a wooden interior, a large window with a view, a chandelier, and a flat-screen TV.
A bar area with a wooden counter, a clock, and shelves with bottles.
A pool area with a long, narrow pool, surrounded by plants and trees. There are outdoor seating areas and a building with large windows in the background.
A rustic interior with exposed brick walls, a wooden floor, and a staircase leading to a balcony.

13. La Alondra Casa De Huéspedes

La Alondra Casa De Huéspedes
Corrientes
United States
Ken
$87 nightly
$87 total
Oct 5 - Oct 6
La Alondra Casa De Huéspedes
An indoor atrium with multiple levels connected by escalators, featuring a central water feature and a variety of arcade machines.
A poolside area with lounge chairs and umbrellas, a modern building with large windows, and a clear blue sky.
A spacious lobby with a glass ceiling, modern furniture, and potted plants.
A modern outdoor lounge area with seating and a view of palm trees and a distant cityscape.

14. Pullman Rosario City Center Hotel

Pullman Rosario City Center Hotel
Rosario
Netherlands
Eric GJ
$128 nightly
$128 total
Oct 1 - Oct 2
Pullman Rosario City Center Hotel
A rooftop pool with a clear view of the city skyline at dusk.
A hotel entrance with a large illuminated sign reading "ROS TOWER HOTEL - SPA & CONVENTION CENTER".
A modern hotel lobby with a marble floor, a staircase, and a dining area with tables and chairs.
A spacious lobby with a polished marble floor, a central staircase, and a large wooden column.

15. Ros Tower Hotel

Ros Tower Hotel
Rosario Centro
United States
AgustĂ­n
$89 nightly
$89 total
Oct 6 - Oct 7
Ros Tower Hotel
A modern hotel lobby with a marble floor, a reception desk, and a long corridor with wooden accents.
A modern hotel room with a sofa, two armchairs, a small round table, a bed, a TV, and a large window with curtains.
A buffet with various food items and utensils.
A modern hotel corridor with a marble floor, dark walls, and a patterned wall on the right.

16. Azahar Hotel & Spa

Azahar Hotel & Spa
San Pedro
United States
Guido
Azahar Hotel & Spa
A modern interior with a glass staircase, seating area, and a view of the sky.
A buffet with various food items including fruits, pastries, and desserts.
A hotel room with a bed, a desk, a chair, and a window with curtains.
A modern hotel lobby with a reception desk, seating area with sofas and armchairs, and a large window providing a view of the outside.

17. Hotel Solans Presidente

Hotel Solans Presidente
Rosario Centro
United States
Juan
$82 nightly
$82 total
Oct 4 - Oct 5
Hotel Solans Presidente
Room
City view
Room
Reception

18. Ámbar Suites

Ámbar Suites
Rosario Centro
Ámbar Suites
A wooden deck with wicker furniture and a glass table, leading to a bedroom with a bed and a robe hanging.
A clear blue pool with lounge chairs and palm trees, surrounded by buildings.
A spacious interior with a high ceiling, wooden beams, a central wooden structure with a staircase, and a glass door leading to a smaller room.
A building with a curved roof, a central entrance, and a sign reading "Centro Posada".

19. Hotel Maitei Posadas

Hotel Maitei Posadas
Posadas
United States
Fredy
Hotel Maitei Posadas
Pool
Room
Pool
Spa

20. HOTEL TERMAS VICTORIA Wellness Spa

HOTEL TERMAS VICTORIA Wellness Spa
Victoria
Spain
Mariela Emilia
$122 nightly
$122 total
Sep 30 - Oct 1
HOTEL TERMAS VICTORIA Wellness Spa
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mesopotamia.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mesopotamia

The awe-inspiring IguazĂș Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.

See all hotels in Mesopotamia
A waterfall surrounded by dense forest and small islands.

Top Mesopotamia Hotel Reviews

Esplendor by Wyndham Savoy Rosario

Esplendor by Wyndham Savoy Rosario

10/10 Excellent
"Hotel muy recomendable para disfrutar del centro de Rosario. Bar de moda en la planta baja."
Omar 1-night trip
Posted 7 days ago
Esplendor by Wyndham Savoy Rosario
Holiday Inn Rosario by IHG

Holiday Inn Rosario by IHG

10/10 Excellent
"👍"
Sean Anthony 5-night trip
Posted 7 days ago
Holiday Inn Rosario by IHG
La Alondra Casa De Huéspedes

La Alondra Casa De Huéspedes

10/10 Excellent
"clean, friendly staff and great ambiance"
Christian 1-night trip
Posted 2 weeks ago
La Alondra Casa De Huéspedes

Find out more about Mesopotamia

Mesopotamia Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Mesopotamia, Argentina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Mesopotamia 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Mesopotamia. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Mesopotamia, Argentina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Mesopotamia hotels offer everything your heart desires.

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